A one-pot remote allylic hydroxylation and Baeyer-Villiger oxidation of a bicyclo[3.2.0]hept-2-en-6-one by Cunninghamella echinulata NRRL 3655

Organic and Biomolecular Chemistry

Volumn 2, Issue 13, 2004, Pages 1831-1833

  Fairlamb, Ian J S ^a   Grant, Stephanie ^a   Grogan, Gideon ^a   Maddrell, David A ^a   Nichols, Josephine C ^a  

^a UNIVERSITY OF YORK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; ENZYMES; FUNGI; GAS CHROMATOGRAPHY; HYDROLYSIS; HYDROXYLATION; NUCLEAR MAGNETIC RESONANCE; OXIDATION;

BIOTRANSFORMATIONS; DOUBLE BONDS; RACEMIC MIXTURES; REACTION MIXTURES;

ORGANIC COMPOUNDS;

CUNNINGHAMELLA; CUNNINGHAMELLA ECHINULATA; FUNGI;

BICYCLO COMPOUND; BICYCLO(3,2,0)HEPT 2 EN 6 ONE; BICYCLO(3,2,0)HEPT-2-EN-6-ONE; LACTONE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CUNNINGHAMELLA; GAS CHROMATOGRAPHY; HYDROXYLATION; METABOLISM; OXIDATION REDUCTION REACTION;

BICYCLO COMPOUNDS; CHROMATOGRAPHY, GAS; CUNNINGHAMELLA; HYDROXYLATION; LACTONES; MOLECULAR STRUCTURE; OXIDATION-REDUCTION;

EID: 3142740923     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b406016d     Document Type: Article

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16. We have so far been unable to determine the optical purity or absolute configuration of compound 8. We are currently identifying a general synthetic route to racemic 8, which will help us to determine this. Furthermore, we hope to derivatise 8 to facilitate a determination of the absolute configuration. These studies are ongoing and will be reported in a full paper.