Anti-GQ1b ganglioside antibody in peripheral nervous system disorders: Pathophysiologic role and clinical relevance

Archives of Neurology

Volumn 61, Issue 7, 2004, Pages 1013-1016

  Paparounas, Konstantinos ^a  

^a G HATZIKOSTA GENERAL HOSPITAL   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

GANGLIOSIDE ANTIBODY; GANGLIOSIDE GQ 1B; GANGLIOSIDE GQ 1B ANTIBODY; GLYCOSPHINGOLIPID; UNCLASSIFIED DRUG;

ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; AREFLEXIA; ATAXIA; AUTOIMMUNE DISEASE; BICKERSTAFF ENCEPHALITIS; BRAIN STEM; CONVALESCENCE; DISEASE CLASSIFICATION; ENCEPHALITIS; GUILLAIN BARRE SYNDROME; HUMAN; MEDICAL LITERATURE; NEUROPATHOLOGY; OPHTHALMOPLEGIA; PATHOPHYSIOLOGY; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; REVIEW; SEROLOGY;

ANIMALS; AUTOANTIBODIES; GANGLIOSIDES; HUMANS; PERIPHERAL NERVOUS SYSTEM DISEASES;

EID: 3142735155     PISSN: 00039942     EISSN: None     Source Type: Journal    
DOI: 10.1001/archneur.61.7.1013     Document Type: Review

References (47)

1. Ledeen R. Gangliosides of the neuron. Trends Neurosci. 1985;8:169-174.
2. Svennerholm L. Chromatographic separation of gangliosides. J Neurochem. 1963: 10:613-623.
3. Pankkezhum DT, Brewer GJ. Gangliosides and synaptic transmission. Biochim Biophys Acta. 1990;1031:277-289.
4. van Heyningen WE, Carpenter CCJ, Pierce NF, Greenough WBI. Deactivation of cholera toxin by ganglioside. J Infect Dis. 1971;124:415-418.
5. Fishman PH, Pacuszka T, Orlandi PA. Gangliosides as receptors for bacterial enterotoxins. Adv Upid Res. 1993;25:165-187.
6. Fisher M. An unusual variant of acute idiopathic polyneuritis (syndrome of ophthalmoplegia, ataxia and areflexia). N Engl J Med. 1956;255:57-65.
7. McKhann GM, Cornblath DR, Griffin JW, et al. Acute motor axonal neuropathy: a frequent cause of acute flaccid paralysis in China. Ann Neurol. 1993:33:333-342.
8. Griffin JW, Li CY, Ho TW, et al. Pathology of the motor-sensory axonal Guillain-Barré syndrome. Ann Neurol. 1996:39:17-28.
9. Yuki N, Kuwabara S, Koga M, Hirata K. Acute motor axonal neuropathy and acute motor-sensory axonal neuropathy share a common immunological profile. J Neurol Sci. 1999;168:121-126.
10. Chiba A, Kusunoki S, Shimizu T, Kanazawa I. Serum IgG antibody to ganglioside GQ1b is a possible marker of Miller Fisher syndrome. Ann Neurol. 1992;31:677-679.
11. Yuki N, Sato S, Tsuji S, Ohsawa T, Miyatake T. Frequent presence of anti-GQ1b antibody in Fisher's syndrome. Neurology. 1993;43:414-417.
12. Willison HJ, Veitch J, Paterson G, Kennedy PGE. Miller Fisher syndrome is associated with serum antibodies to GQ1b ganglioside. J Neurol Neurosurg Psychiatry. 1993;56:204-206.
13. Koga M, Yuki N, Takahashi M, Saito K, Hirata K. Close association of IgA antiganglioside antibodies with antecedent Campylobacter jejuni infection in Guillain-Barré and Fisher's syndromes. J Neuroimmunol. 1998;81:138-143.
14. Jacobs BC, Endtz HP, van der Meché FGA, Hazenberg MP, Achtereecte HAM, van Doorn PA. Serum anti-GQ1b IgG antibodies recognize surface epitopes on Campylobacter jejuni from patients with Miller Fisher syndrome. Ann Neurol. 1995;37:260-264.
15. Neisser A, Bernheimer H, Berger T, Moran AP, Schwerer B. Serum antibodies against gangliosides and Campylobacter jejuni lipopolysaccharides in Miller Fisher syndrome. Infect Immun. 1997;65:4038-4042.
16. Chiba A, Kusunoki S, Obata H, Machinami R, Kanazawa I. Serum anti-GQ1b IgG antibody is associated with ophthalmoplegia in Miller Fisher syndrome and Guillain-Barré syndrome: clinical and immunohistochemical studies. Neurology. 1993; 43:1911-1917.
17. O'Leary CP, Veitch J, Durward WF, Thomas AM, Rees JH, Willison HJ. Acute oropharyngeal palsy is associated with antibodies to GQ1b and GT1a gangliosides. J Neurol Neurosurg Psychiatry. 1996;61:649-651.
18. Koga M, Yuki N, Ariga T, Morimatsu M, Hirata K. Is IgG anti-GT1a antibody associated with pharyngeal-cervical-brachial weakness or oropharyngeal palsy in Guillain-Barré syndrome? J Neuroimmunol. 1998;86:74-79.
19. Ropper AH. Unusual clinical variants and signs in Guillain-Barré syndrome. Arch Neurol. 1986;43:1150-1152.
20. Kornberg AJ, Pestronk A, Blume GM, Lopate G, Yue J, Hahn A. Selective staining of the cerebellar molecular layer by serum IgG in Miller Fisher and related syndromes. Neurology. 1996;47:1317-1320.
21. Kusunoki S, Chiba A, Kanazawa I. Anti-GQ1b IgG antibody is associated with ataxia as well as ophthalmoplegia. Muscle Nerve. 1999;22:1071-1074.
22. Mizoguchi K, Uchiyama T, Obi T, Serizawa M, Nishimura Y. Anti-GQ1b and anti-GT1 a IgG antibodies in a patient with acute demyelinating polyradiculoneuropathy without ophthalmoplegia. J Neurol Neurosurg Psychiatry. 1997;63;410-411.
23. Mori M, Kuwabara S, Koga M, et al. IgG anti-GQ1b positive acute ataxia without ophthalmoplegia. J Neurol Neurosurg Psychiatry. 1999;67:668-670.
24. Yuki N. Acute paresis of extraocular muscles associated with IgG anti GQ1b antibody. Ann Neurol. 1996;39:668-672.
25. Yuki N, Odaka M, Hirata K. Acute ophthalmoparesis (without ataxia) associated with anti-GQ1b IgG antibody. Ophthalmology. 2001;108:196-200.
26. Yuki N, Koga M, Hirata K. Isolated internal ophthalmoplegia associated with immunoglobulin G anti-GQ1b antibody. Neurology. 1998;51:1515-1516.
27. Bickerstaff ER, Cloake PCP. Mesencephalitis and rhombencephalitis. BMJ. 1951; 2:77-81.
28. Bickerstaff ER. Brain-stem encephalitis: further observations on a grave syndrome with benign prognosis. BMJ. 1957;1:1384-1387.
29. Mizoguchi K. Anti-GQ1b IgG antibody activities related to the severity of Miller Fisher syndrome. Neurol Res. 1998;20:617-624.
30. Chiba A, Kusunoki S, Obata H, Machinami R, Kanazawa I. Ganglioside composition of the human cranial nerves, with special reference to the pathophysiology of Miller Fisher syndrome. Brain Res. 1997;745:32-36.
31. Jamal GA, Ballantyne JP. The localization of the lesion in patients with acute ophthalmoplegia, ataxia, and areflexia (Miller Fisher syndrome): a serial multimodal neurophysiological study. Brain. 1988;111:95-114.
32. Al-Din AN, Anderson M, Bickerstaff ER, Harvey I. Brainstem encephalitis and the syndrome of Miller Fisher: a clinical study. Brain. 1982;105:481-495.
33. Yuki N, Sato S, Tsuji S, Hozumi I, Miyatake T. An immunologic abnormality common to Bickerstaff's brain stem encephalitis and Fisher's syndrome. J Neurol Sci. 1993;118:83-87.
34. Ogawara K, Kuwabara S, Yuki N. Fisher syndrome or Bickerstaff brainstem encephalitis? anti-GQ1b IgG antibody syndrome involving both the peripheral and central nervous system. Muscle Nerve. 2002;26:845-849.
35. Toyka KV, Drachman DB, Griffin DE, et al. Myasthenia gravis: study of humoral immune mechanisms by passive transfer to mice. N Engl J Med. 1977;296:125-131.
36. Witebsky E, Rose NR, Terplan K, Paine JR, Egan RW. Chronic thyroiditis and autoimmunization. JAMA. 1957;164:1439-1447.
37. Roberts M, Willison HJ, Vincent A, Newsom-Davis J. Serum factor in Miller Fisher variant of Guillain-Barré syndrome and neurotransmitter release. Lancet. 1994; 343:454-455.
38. Plomp JJ, Molenaar PC, O' Hanlon GM, et al. Miller Fisher anti-GQ1b antibodies: α-latrotoxin-like effects on motor end plates. Ann Neurol. 1999;45:189-199.
39. Buchwald B, Ahangari R, Toyka KV. Differential blocking effects of the monoclonal anti-GQ1b IgM antibody and alpha-latrotoxin in the absence of complement at the mouse neuromuscular junction. Neurosci Lett. 2002;334:25-28.
40. O' Hanlon GM, Plomp JJ, Chakrabarti M. et al. Anti-GQ1b ganglioside antibodies mediate complement-dependent destruction of the motor nerve terminal. Brain. 2001;124:893-906.
41. Bullens RWM, O' Hanlon GM, Goodyear CS, et al. Anti-GQ1b antibodies and evoked acetylcholine release at mouse motor endplates. Muscle Nerve. 2000;23:1035-1043.
42. Buchwald B, Weishaupt A, Toyka KV, Dudel J. Pre- and postsynaptic blockade of neuromuscular transmission by Miller Fisher syndrome IgG at mouse motor nerve terminals. Eur J Neurosci. 1998;10:281-290.
43. Buchwald B, Bufler J, Carpo M, et al. Combined pre- and postsynaptic action of IgG antibodies in Miller Fisher syndrome. Neurology. 2001;56:67-74.
44. Hubbard JI, Jones SF, Landau EM. An examination of the effects of osmotic pressure changes upon transmitter release from mammalian motor nerve terminals. J Physiol. 1968;197:639-657.
45. Kusunoki S, Shimizu J, Chiba A, Ugawa Y, Hitoshi S, Kanazawa I. Experimental sensory neuropathy induced by sensitization with ganglioside GD1b. Ann Neurol. 1996;39:424-431.
46. Rose NR, Bona C. Defining criteria for autoimmune diseases (Witebsky's postulates revisited). Immunol Today. 1993:14:426-430.
47. McFarlin DE. Immunological parameters in Guillain-Barré syndrome. Ann Neurol. 1990;27:S25-S29.