An effective strategy for the co-production of S-adenosyl-L-methionine and glutathione by fed-batch fermentation

Biochemical Engineering Journal

Volumn 21, Issue 1, 2004, Pages 19-25

  Lin, Jian Ping ^a   Tian, Jun ^a   You, Jian Feng ^a   Jin, Zhi Hua ^a   Xu, Zhi Nan ^a   Cen, Pei Lin ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Bioconversion; Fed batch culture; Glutathione; Optimization; S adenosyl L methionine; Yeast

Indexed keywords

CELLS; MEDICAL APPLICATIONS; PHYSIOLOGY; SYNTHESIS (CHEMICAL); YEAST;

FED-BATCH CULTURES; FED-BATCH FERMENTATION; TRANSFORMATION PHASES;

FERMENTATION;

ALCOHOL; GLUCOSE; S ADENOSYLMETHIONINE;

ALCOHOL PRODUCTION; ARTICLE; BIOTRANSFORMATION; CELL DENSITY; CHEMICAL MODIFICATION; DENSITY; FED BATCH FERMENTATION; PHYSIOLOGY; PRECURSOR; PRIORITY JOURNAL; REDUCTION; YEAST CELL;

EID: 3142733452     PISSN: 1369703X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bej.2004.04.013     Document Type: Article

References (20)

1. Cantoni G.L. The nature of the active methyl donor formed enzymatically from L-methionine and adenosine triphosphate. J. Am. Chem. Soc. 74:1952;2942-2943
2. Barcelo H.A., Wiemeyer J.C., Sagasta C.L., Macias J.C., Barreira J.C. Experimental osteoarthritis and its course when treated with S-adenosyl-L-methionine. Rev. Clin. Esp. 187:1990;74-78
3. Torta R., Cicolin A., Keller R. Transmethylation and affective disorders. Arch. Gerontol. Geriatr. Suppl. 6:1998;499-506
4. Lieber C.S. Role of S-adenosyl-L-methionine in the treatment of liver diseases. J. Hepatol. 30(6):1999;1155-1159
5. Camera E., Picardo M. Analytical methods to investigate glutathione and related compounds in biological and pathological processes. J. Chromatogr. B. 781(1-2):2002;181-206
6. Townsend D.M., Tew K.D., Tapiero H. The importance of glutathione in human disease. Biomed. Pharmacother. 57(3):2003;145-155
7. Mincheva K., Kamburova V., Balutzov V. Production of S-adenosyl-L- methionine by a mutant strain of Kluyveromyces lactis. Biotechnol. Lett. 24:2002;985-988
8. Mincheva K., Kamburova V., Balutzov V. Optimization of S-adenosyl-L-methionine production by Kluyveromyces lactis on whey in batch culture using a mathematical model. Biotechnol. Lett. 24:2002;1773-1777
9. Liu C.H., Hwang C.F., Liao C.C. Medium optimization for glutathione production by Saccharomyces cerevisiae. Process Biochem. 34(1):1999;17-23
10. Lu S.C. S-adenosylmethionine. Int. J. Biochem. Cell Bio. 32:2000;391-395
11. H. Liu, J.P. Lin, P.L. Cen, Y.J. Pan, Co-production of S-adenosyl-L-methionine and glutathione with spent brew's yeast cells, Process Biochem., in press.
12. Liu H., Lin J.P., Wu J.P., Cen P.L. Production of S-adenosyl-L-methionine using Saccharomyces cerevisiae by bioconversion of L-methionine. Chem. React. Eng. Tech. (China). 18(4):2002;310-314
13. Wang H.Y., Cooney C.L., Wang D.I.C. Computer-aided backer's yeast fermentations. Biotech. Bioeng. 19:1977;69-86
14. Wang H.Y., Cooney C.L., Wang D.I.C. Computer control of backer's yeast production. Biotech. Bioeng. 21:1979;975-995
15. Mendoza-Vega O., Sabatie J., Brown S.W. Industrial production of heterologous proteins by fed-batch cultures of the yeast Saccharomyces cerevisiae. FEMS Microbiol. Rev. 15:1994;369-410
16. Miller G.L. Use of dinitrosalicylic acid reagent for the determination of reducing sugar. Anal. Chem. 31:1959;426-428
17. Owens C.W.I., Belcher R.V. A colorimetric micro-method for the determination of glutathione. Biochem. J. 94:1965;706-711
18. O'Connor G.M., Sanchez-Riera F., Cooney C.L. Design and evaluation of control strategies for high cell density fermentations. Biotechnol. Bioeng. 39:1992;293-304
19. Sonnleitner B., Käppeli O. Growth of Saccharomyces cerevisiae is controlled by the limited respiratory capacity: formulation and verification of a hypothesis. Biotechnol. Bioeng. 28:1986;927-937
20. Di Serio M., Tesser R., Santacesaria E. A kinetic and mass transfer model to simulate the growth of baker's yeast in industrial bioreactors. Chem. Eng. J. 82(1-3):2001;347-354