Systematically experimental investigation on carcinogenesis or tumorigenicity of VERO cell lines of different karyotypes in nude mice in vivo used for viral vaccine manufacture

Acta Genetica Sinica

Volumn 31, Issue 7, 2004, Pages 647-660

  Zhang, De Li ^a,b,c   Ji, Liang ^b,c   Li, Liu Jin ^d   Huang, Gao Sheng ^d  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b TSINGHUA UNIVERSITY   (China)

^c TSINGHUA NATIONAL LABORATORY FOR INFORMATION SCIENCE AND TECHNOLOGY   (China)

^d FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

African green monkey kidney cell line; Carcinogenesis toxicology; Nude mice; Tumorigenesis; VERO

Indexed keywords

LIVE VACCINE; RABIES VACCINE;

ADENOVIRUS 2; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANINE DISTEMPER MORBILLIVIRUS; CARCINOGENESIS; CARCINOGENICITY; CAT; CELL STRAIN BHK; CHINA; CHROMOSOME BAND; COLONY FORMATION; CONTROLLED STUDY; DOG; FEMALE; HELA CELL; HUMAN; HUMAN CELL; IN VIVO STUDY; KARYOTYPE; MALE; MINK; MOUSE; NONHUMAN; NUDE MOUSE; PARAINFLUENZA VIRUS; PARVOVIRUS; RABIES VIRUS; RHABDOID TUMOR; SPECIES DIFFERENCE; VACCINE PRODUCTION; VERO CELL;

ANIMALS; CATS; CERCOPITHECUS AETHIOPS; DOGS; HELA CELLS; HUMANS; KARYOTYPING; MICE; MICE, NUDE; NEOPLASMS, EXPERIMENTAL; SPECIES SPECIFICITY; VERO CELLS; VIRAL VACCINES;

ADENOVIRIDAE; ANIMALIA; CANINE DISTEMPER VIRUS; CANIS FAMILIARIS; CERCOPITHECUS AETHIOPS; FELIDAE; FELIS CATUS; HUMAN ADENOVIRUS TYPE 2; MUS MUSCULUS; MUSTELA VISON; PARVOVIRUS; RABIES VIRUS;

EID: 3142728436     PISSN: 03794172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Lubiniecki A S. Continuous cell substrate considerations. Bioprocess Technol, 1990, 10: 495-513.
2. Pearson J. Changing issues of quality control: diploid and non-diploid cell lines. Dev Biol Stand, 1992, 76: 13-17.
3. Petricciani J C, Horaud F N. Karyology and tumorigenicity testing requirements: past, present and future. Dev Biol Stand, 1998, 93: 5-13.
4. Lee C K. Issues of biological assays for viral vaccines. Dev Biol Stand, 1996, 88: 41-47.
5. Petricciani J C. Cell substrates: lessons learned and challenges remaining. Dev Biol Stand, 1999, 100: 57-63.
6. Lower J. Risk of tumor induction in vivo by residual cellular DNA: quantitative considerations. J Med Virol, 1990, 31 (1): 50-53.
7. Krause P R, Lewis A M Jr. Safety of viral DNA in biological products. Biologicals, 1998, 26(4): 317-320.
8. Zhang D L. Carcinogenesis or tumourigenicity testing of animal cell lines for vaccine preparation by colony formation on soft agar and by agglutination under plant lectins. Cell Biology International, 2001, 25: 997-1002.
9. ZHANG De-Li, LI Liu-Jin, XIA Geng-Tian, HE Xu-Yu, GAO Bu-Xian, BAI Xiao-Hong, HUANG Gao-Sheng, LIU Shang-Gao, YAN Long-Fei, FANG Fu-De. Analyses of chromosomal karyotypes and cytogenetic variations of animal cell lines. Acta Genetica Sinica, 2001, 28(4): 327-344.
10. ZHANG De-Li, HUANG Gao-Sheng, LI Liu-Jin, HE Xu-Yu, XIA Geng-Tian, GAO Bu-Xian, BAI Xiao-Hong, LIU Shang-Gao. Studies of the origin of malignant rhabdoid tumor (MRT)-experimental researches on the MRT evolving in nude mice inoculated with violently variable HeLa cells. Acta Genetica Sinica, 2000, 27(12): 1057-1071.
11. Tsareva A A, Isaenko A A, unmanova M A. A karyotype study of the VERO cell line cultured long term in a mono-layer by static and roller methods. Tsitologiya (USSR; Russian with English abstract), 1990, 32(7): 749.
12. de Sahum S B, Lampa I, Damonte E B, Coto C E. Cytogenetic analysis of VERO cell lines. Medicina(B Seres) (Argentina), 1978, 38(5): 513-518.
13. Desatum S B, Larripa I, Damonte E B. Identification of 2 VERO cell lines by C-banding technique. Medicina-Buenos Aires(in Spanish language), 1978, 78(5): 519.
14. Rhim J S, Schell K, Creasy B. Biological characteristics and viral susceptibility of an African green monkey kidney cell line(VERO). Proc Soc Exp Biol Med(USA), 1969, 132: 670-678.
15. Zhang D L. Studies on isolation, serum-free cultivation and manufacture of mink enteritis virus optimized for vaccine preparation. Biologicals, 1997, 25(1): 103-111.
16. Zhang D L, Yin Z, Wang S Z. Evaluation of immune response and protection in animals given mink parvovirus vaccines. Biologicals, 1997, 25(1): 93-101.
17. Rather R, Becker B C, Contreras G. Heterotransplantation studies with tissue culture cell lines in various animal and in vitro host systems. J Biological Standardization, 1985, 13: 13-22.
18. Levenbook I S, Petricciani J C, Qi Y B. Tumorigenicity testing of primate cell lines in nude mice, muscle organ culture and for colony formation in soft agarose. J Biol Stand, 1985, 13: 135-141.
19. Kahn P, Shin S I. Cellular tumorigenicity in nude mice. Tests of associations among loss of cell-surface fibronectin, anchorage independence, and tumor-forming ability. J Cell Biol, 1979, 82: 1-16.
20. Nelson W J. The distribution of spontaneous chromosome aberrations in BHK21/C13 fibroblasts. Mutat Res(Netherlands), 1979, 59: 195-201.
21. Thomas J A, Fouquet J P, Hollande E. A comparative study of the mitochondria and karyotypes of BHK21/13 cells and H54 cancer cells derived from them. C R Aad Sci Ser D (French), 1964, 258 (25, Group 14): 6273-6276.
22. Furesz J, Fanok A, Contreras G. Tumorigenicity testing of various cell substrates for production of biologicals. Develop Biol Standard, 1989, 70: 233-243.
23. Wayne R K, Nash W G, O'Brien S J. Chromosomal evolution of the Canidae. II. Divergence from the primitive carnivore karyotype. Cytogenet Cell Genet, 1987, 44(2-3): 134-141.
24. Cho K W, Youn H Y, Watari T. A proposed nomenclature of the domestic cat karyotype. Cytogenet Cell Genet, 1997, 79(1-2): 71-78.
25. Bouck N, Head M. The majority of independently transformed BHK cell clones share a single functional lesion which determines anchorage independence and influences tumorigenicity. In Vitro Cell Dev Biol, 1985, 21(8): 463-469.
26. Berman L D. Lack of correlation between growth characteristics, agglutinability by plant lectins and the malignant phenotype. Int J Cancer, 1975, 15(6):973-979.
27. Petricciani J C, Horaud F N. Karyology and tumorigenicity testing requirements: past, present and future. Dev Biol Stand, 1998, 93: 5-13.
28. Klein A S, Plata F, Jackson M J, Shin S. Cellular tumorigenicity in nude mice. Role of susceptibility to natural killer cells. Exp Cell Biol, 1979, 47(6): 430-445.
29. Regan P J, Petricciani J C. The approach used to establish the safety of veterinary vaccines produced in the BHK 21 cell line. Dev Biol Stand, 1987, 68: 19-25.
30. Petricciani J C. Cells, Science and Health. Dev Biol Standard, 1989, 70: 3-10.
31. Amadori M, Volpe G, Defilippi P, Berneri C. Phenotypic features of BHK-21 cells used for production of foot-and-mouth disease vaccine. Biologicals, 1997, 25(1): 65-73.
32. Pay T W, Boge A, Menard F J. Production of rabies vaccine by an industrial scale BHK-21 suspension cell culture process. Dev Biol Stand, 1985, 60: 71-74.
33. El-Karamany R M. Production in VERO cells of an inactivated rabies vaccine from strain FRV/K for animal and human use. Acta Virol, 1987, 31(4): 321-328.
34. Benmansour A, Khellaf F. Immunogenicity and protective activity induced in dogs by experimental rabies vaccines of cell culture origin. Arch Inst Pasteur Alger(French), 1986, 54: 130-150.
35. Blancou J, Aubert M F A, Andral L. Studies on pathogenic, immunogenic, and protective efficiency of fox rabies virus before and after adaptation to cell culture: Application to vaccination against rabies. Can J Microbiol, 1983, 29(1): 77-83.
36. Wick M R, Ritter J H, Dehner L P. Malignant rhabdoid tumors: a clinicopathologic review and conceptual discussion. Semi Diagn Pathol, 1995, 12(3): 233-248.
37. Shamberger R C. Pediatric renal tumors. Semin Surg Oncol, 1999, 16(2): 105-120.
38. Cho K R, Rosenshein N B, Epstein J I. Malignant rhabdoid tumor of the uterus. Int J Gynecol Pathol, 1989, 8(4): 381 -387.
39. Hsueh S, Chang T C. Malignant rhabdoid tumor of the uterine corpus. Gynecol Oncol, 1996, 61(1): 142-146.
40. LIU Yu, LI Pei-Juan, LIU Shu-Rong, HUANG Cheng-Ru, SUN Ning. Malignant rhabdoid tumor of kidney: a clinicopathologic and immunohistochemical study of 15 patients. Chung Hua Ping Li Hsueh Tsa Chih, 1995, 24(2): 72-74.
41. Schauer G, Moll R, Walter J H. Malignant rhabdoid tumor in the gastric wall of an aged orangutan(Pongo pygmaeus). Vet Pathol, 1994, 31(5): 510-517.
42. Steele K E, Schulman F Y, Mena H. Rhabdoid tumor in the brain of a dog. Vet Pathol, 1997, 34(4): 359-363.
43. Blau H M, Brazelton T R, Weimann J M. The Evolving Concept of a Stem Cell. Entity or Function? Cell, 2001, 105 (7):829-841.
44. Krause D S, Theise N D, Collector M I, Henegariu O, Hwang S, Gardner R, Neutzel S, Sharkis S J. Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell, 2001: 105(3): 369-377.
45. Zuk P A, Prockop D J. Stem cell research has only just begun. Science, 2001, 293(5528): 211-212.
46. Vogel G. Stem cell research. NIH review outlines 'enormous promise'. Science, 2001, 293(5529): 413-432.
47. Shannon B, Stan Wisniewski Z, Bentel J, Cohen R J. Adult rhabdoid renal cell carcinoma. Arch Pathol Lab Med, 2002, 126(12): 1506-1510.