A short and efficient synthesis of a chiral pyridazinone derivative by the chiral-pool method

Synthesis

Volumn , Issue 10, 2004, Pages 1554-1556

  Yoshida, Noriyuki ^a,b   Awano, Katsuya ^a   Kobayashi, Tomoshige ^b   Fujimori, Kunihide ^b  

^a KYORIN PHARMACEUTICAL CO LTD   (Japan)

^b SHINSHU UNIVERSITY   (Japan)

Author keywords

Asymmetric synthesis; Chiral pool; Inhibitors; Pyrazolopyridine; Pyridazinone

Indexed keywords

DERIVATIVES; ENZYMES; KETONES; STEREOCHEMISTRY;

CHIRAL POOL METHOD; OPTICAL YIELDS;

SYNTHESIS (CHEMICAL);

2 CHLOROPROPIONYL CHLORIDE; 4,5 DIHYDRO 6 (2 ISOPROPYLPYRAZOLO[1,5 A]PYRIDIN 3 YL) 5 METHYLPYRIDAZIN 3(2H) ONE; CHLORIDE; PHOSPHODIESTERASE INHIBITOR; PYRIDAZINONE DERIVATIVE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; ASYMMETRIC SYNTHESIS; CATALYSIS; CATALYST; CHEMICAL REACTION; CHIRALITY; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 3142704419     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-829107     Document Type: Article

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