Efficacy of a single milbemycin oxime administration in combination with praziquantel against experimentally induced heartworm (Dirofilaria immitis) infection in cats

Veterinary Parasitology

Volumn 122, Issue 4, 2004, Pages 287-292

  Genchi, Claudio ^a   Cody, Robert ^b   Pengo, Graziano ^c   Büscher, Gottfried ^b   Cavalleri, Daniela ^b   Bucci, Valeria ^d   Junquera, Pablo ^e  

^a UNIVERSITY OF MILAN   (Italy)

^b NOVARTIS PHARMA AG   (Switzerland)

^c Centro Veterinario Oriolo   (Italy)

^d Novartis Salute Animale   (Italy)

^e Vetparcs GmbH   (Switzerland)

Author keywords

Cat; Efficacy; Heartworm; Milbemycin oxime

Indexed keywords

ANTHELMINTIC AGENT; ANTIPARASITIC AGENT; MILBEMYCIN; PRAZIQUANTEL;

ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CAT DISEASE; CONTROLLED STUDY; DIROFILARIA IMMITIS; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG MECHANISM; EXPERIMENTAL INFECTION; FEMALE; FILARIASIS; INFECTION PREVENTION; MALE; NONHUMAN; SINGLE DRUG DOSE; TABLET;

ANIMALS; ANTHELMINTICS; CAT DISEASES; CATS; DIROFILARIA IMMITIS; DIROFILARIASIS; DRUG THERAPY, COMBINATION; FEMALE; MACROLIDES; MALE; PRAZIQUANTEL; RANDOM ALLOCATION; TREATMENT OUTCOME;

ANIMALIA; DIROFILARIA IMMITIS; FELIS CATUS;

EID: 3142703168     PISSN: 03044017     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetpar.2004.04.011     Document Type: Article

References (21)

1. Andrews P., Thomas H., Pohlke R., Seubert J. Praziquantel. Med. Res. Rev. 3:1983;147-200
2. Blagburn, B.L., Hendrix, C.M., Vaughan, J.L., Lindsay, D.S., Tebbit, G.L., 1995. Efficacy of a chewable formulation of milbemycin oxime against preadult Dirofilaria immitis and adult Ancylostoma caninum in naturally and experimentally infected dogs. In: Soll, M.D. (Ed.), Proceedings of the Heartworm Symposium'95. American Heartworm Society, Batavia, IL, pp. 171-175.
3. Bowman D.D., Johnson R.C., Hepler D.I. Effects of milbemycin oxime on adult hookworms in dogs with naturally acquired infections. Am. J. Vet. Res. 51:1990;487-490
4. Bowman D.D., Lin D.S., Johnson R.C., Hepler D.I. Effects of milbemycin oxime on adult Ancylostoma caninum and Uncinaria stenocephala in dogs with experimentally induced infections. Am. J. Vet. Res. 52:1991;64-67
5. Bowman, D.D., Johnson, R.D., Fogelson, M., Hepler, D.I., 1991b. Effects of milbemycin oxime on adult ascarids (Toxocara cati) in cats with naturally acquired infections. In: Proceedings of the 36th Annual Meeting of the American Association of Veterinary Parasitologists, Abstract no. 16.
6. Dillon R. Clinical significance of feline heartworm disease. Vet. Clin. North Am.: Small An. Pract. 28:1998;1547-1565
7. Doiron, D.W., Dowimg, R., Longhofer, S.L., Nelson, C.T., Rubin, S.B., McCall, J.W., Knight, D.H., Seward, R.L., 2001. 2002 guidelines for the diagnosis, prevention and management of heartworm (Dirofilaria immitis) infection in cats. In: Seward, R.L., Knight, D.H. (Eds.), Proceedings of the Recent Advances in Heartworm Disease: Symposium'01. American Heartworm Society, Batavia, IL, pp. 267-273.
8. Fukase, T., McCall, J.W., Akihama, S., 1996. Evaluation of milbemycin oxime as a prophylactic agent for heartworm infection in domestic cats. Abstracts of the VII European Multicolloquium of Parasitology, Parma, September 2-6, Abstract D3 10, 232 pp.
9. Genchi, C., Guerrero, J., Di Sacco, B., Formaggini, L., 1992. Prevalence of Dirofilaria immitis in Italian cats. In: Soll, M.D. (Ed.), Proceedings of the Heartworm Symposium'92. American Heartworm Society, Batavia, IL, pp. 97-102.
10. Grieve R.B., Frank G.R., Stewart V.A., Parsons J.C., Belasco D.L., Hepler D.I. Chemoprophylactic effects of milbemycin oxime against larvae of Dirofilaria immitis during prepatent development. Am. J. Vet. Res. 52:1991;2040-2042
11. Guerrero, J., McCall, J.W., Dzimianski, M.T., McTier, T.L., Holmes, R.A., Newcomb, K.H., 1992. Prevalence of Dirofilaria immitis infection in cats from the southeastern United States. In: Soll, M.D. (Ed.), Proceedings of the Heartworm Symposium'92. American Heartworm Society, Batavia, IL, pp. 91-95.
12. Humbert-Droz E., Büscher G., Cavalleri D., Junquera P. Efficacy of milbemycin oxime against Ancylostoma tubaeforme (fourth stage larvae and adults) in artificially infected cats. Vet. Rec. 154:2004;140-143
13. Jacobs D.E., Arakawa A., Courtney C.H., Gemmell M.A., McCall J.W., Myers G.H., Vanparijs O. World Association for the Advancement of Veterinary Parasitology (WAAVP) guidelines for evaluating the efficacy of anthelmintics for dogs and cats. Vet. Parasitol. 52:1994;179-202
14. Kramer L., Genchi C. Feline heartworm infection: serological survey of asymptomatic cats living in northern Italy. Vet. Parasitol. 104:2002;43-50
15. McCall J.W., Calvert C.A., Rawlings C.A. Heartworm infection in cats: a life-threatening disease. Vet. Med. 89:1994;639-647
16. McCall, J.W., Lindemann, B.A., Porter, C.A., 1981. Prophylactic activity of avermectins against experimentally induced Dirofilaria immitis infections in dogs. In: Otto, G.F. (Ed.), Proceedings of the Heartworm Symposium'80. Edwardsville, KS. Veterinary Medicine Publishing Co., pp. 126-130.
17. McTier T.L., Shanks D.J., Watson P., McCall J.W., Genchi C., Six R.H., Thomas C.A., Dickin S.K., Pengo G., Rowan T.G., Jernigan A.D. Prevention of experimentally induced heartworm (Dirofilaria immitis) infections in dogs and cats with a single topical application of selamectin. Vet. Parasitol. 91:2000;259-269
18. Roncalli R.A., Yamane Y., Nagata T. Prevalence of Dirofilaria immitis in cats in Japan. Vet. Parasitol. 75:1998;81-89
19. Stewart, V.A., Blagburn, B.L., Hendrix, C.M., Hepler, D.I., Grieve, R.B., 1992. Milbemycin oxime as an effective preventative of heartworm (Dirofilaria immitis) infection in cats. In: Soll, M.D. (Ed.), Proceedings of the Heartworm Symposium'92. American Heartworm Society, Batavia, IL, pp. 127-131.
20. Tagawa M., Hara Y., Ejima H., Hayashi Y., Kusano K. Prophylactic efficacy of milbemycin oxime against multiple infection of dogs with Dirofilaria immitis. J. Vet. Med. Sci. 56:1994;779-780
21. Tagawa M., Okano S., Hayashi Y., Kusano K. Prophylactic effect of milbemycin oxime against Dirofilaria immitis infection in dogs: optimum dose and administration time. J. Vet. Med. Sci. 55:1993;693-694