메뉴 건너뛰기




Volumn 18, Issue 10, 2004, Pages 1383-1392

HIV-1 Nef is preferentially recognized by CD-8 T cells in primary HIV-1 infection despite a relatively high degree of genetic diversity

Author keywords

Acute HIV 1 infection; Cellular immune responses; Clade B consensus sequence; HIV 1 Nef; HIV specific CD8 T cells; HLA; Viral entropy

Indexed keywords

CD8 ANTIGEN; GAG PROTEIN; NEF PROTEIN; POL PROTEIN; VIRUS ENVELOPE PROTEIN;

EID: 3142683572     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.aids.0000131329.51633.a3     Document Type: Article
Times cited : (102)

References (33)
  • 1
    • 0345064728 scopus 로고    scopus 로고
    • Acute human immunodeficiency virus type 1 infection
    • Kahn JO, Walker BD. Acute human immunodeficiency virus type 1 infection. N Engl J Med 1998, 339:33-39.
    • (1998) N Engl J Med , vol.339 , pp. 33-39
    • Kahn, J.O.1    Walker, B.D.2
  • 2
    • 0025735965 scopus 로고
    • Transient high levels of viremia in patients with primary human immunodeficiency virus type 1 infection
    • Daar ES, Moudgil T, Meyer RD, Ho DD. Transient high levels of viremia in patients with primary human immunodeficiency virus type 1 infection. N Engl J Med 1991, 324:961-964.
    • (1991) N Engl J Med , vol.324 , pp. 961-964
    • Daar, E.S.1    Moudgil, T.2    Meyer, R.D.3    Ho, D.D.4
  • 3
    • 0028041344 scopus 로고
    • Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection
    • Borrow P, Lewicki H, Hahn BH, Shaw CM, Oldstone MB. Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. J Virol 1994, 68:6103-6110.
    • (1994) J Virol , vol.68 , pp. 6103-6110
    • Borrow, P.1    Lewicki, H.2    Hahn, B.H.3    Shaw, C.M.4    Oldstone, M.B.5
  • 4
    • 0028337166 scopus 로고
    • Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
    • Koup RA, Safrit JT, Cao Y, Andrews CA, McLeod C, Borkowsky W, et al. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J Virol 1994, 68:4650-4655.
    • (1994) J Virol , vol.68 , pp. 4650-4655
    • Koup, R.A.1    Safrit, J.T.2    Cao, Y.3    Andrews, C.A.4    McLeod, C.5    Borkowsky, W.6
  • 5
    • 0030997137 scopus 로고    scopus 로고
    • Suppression of human immunodeficiency virus type 1 replication by CD8+ cells: Evidence for HLA class I-restricted triggering of cytolytic and noncytolytic mechanisms
    • Yang OO, Kalams SA, Trocha A, Cao H, Luster A, Johnson RP, et al. Suppression of human immunodeficiency virus type 1 replication by CD8+ cells: evidence for HLA class I-restricted triggering of cytolytic and noncytolytic mechanisms. J Virol 1997, 71:3120-3128.
    • (1997) J Virol , vol.71 , pp. 3120-3128
    • Yang, O.O.1    Kalams, S.A.2    Trocha, A.3    Cao, H.4    Luster, A.5    Johnson, R.P.6
  • 7
    • 0033559648 scopus 로고    scopus 로고
    • Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques
    • Jin X, Bauer DE, Tuttleton SE, Lewin S, Gettie A, Blanchard J, et al. Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques. J Exp Med 1999, 189:991-998.
    • (1999) J Exp Med , vol.189 , pp. 991-998
    • Jin, X.1    Bauer, D.E.2    Tuttleton, S.E.3    Lewin, S.4    Gettie, A.5    Blanchard, J.6
  • 9
    • 0036113306 scopus 로고    scopus 로고
    • Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeficiency virus infection
    • O'Connor DH, Allen TM, Vogel TU, Jing P, DeSouza IP, Dodds E, et al. Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeficiency virus infection. Nat Med 2002, 8:493-499.
    • (2002) Nat Med , vol.8 , pp. 493-499
    • O'Connor, D.H.1    Allen, T.M.2    Vogel, T.U.3    Jing, P.4    Desouza, I.P.5    Dodds, E.6
  • 10
    • 0034699512 scopus 로고    scopus 로고
    • Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia
    • Allen TM, O'Connor DH, Jing P, Dzuris JL, Mothe BR, Vogel TU, et al. Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia. Nature 2000, 407:386-390.
    • (2000) Nature , vol.407 , pp. 386-390
    • Allen, T.M.1    O'Connor, D.H.2    Jing, P.3    Dzuris, J.L.4    Mothe, B.R.5    Vogel, T.U.6
  • 11
  • 12
    • 0035377540 scopus 로고    scopus 로고
    • Immune control of HIV: The obstacles of HLA and viral diversity
    • Walker BD, Korber BT. Immune control of HIV: the obstacles of HLA and viral diversity. Nat Immunol 2001, 2:473-475.
    • (2001) Nat Immunol , vol.2 , pp. 473-475
    • Walker, B.D.1    Korber, B.T.2
  • 13
    • 0037189323 scopus 로고    scopus 로고
    • Diversity considerations in HIV-1 vaccine selection
    • Gaschen B, Taylor J, Yusim K, Foley B, Gao F, Lang D, et al. Diversity considerations in HIV-1 vaccine selection. Science 2002, 296:2354-2360.
    • (2002) Science , vol.296 , pp. 2354-2360
    • Gaschen, B.1    Taylor, J.2    Yusim, K.3    Foley, B.4    Gao, F.5    Lang, D.6
  • 14
    • 0038806352 scopus 로고    scopus 로고
    • Enhanced detection of human immunodeficiency virus type 1-specific T-cell responses to highly variable regions by using peptides based on autologous virus sequences
    • Altfeld M, Addo MM, Shankarappa R, Lee PK, Allen TM, Yu XG, et al. Enhanced detection of human immunodeficiency virus type 1-specific T-cell responses to highly variable regions by using peptides based on autologous virus sequences. J Virol 2003, 77:7330-7340.
    • (2003) J Virol , vol.77 , pp. 7330-7340
    • Altfeld, M.1    Addo, M.M.2    Shankarappa, R.3    Lee, P.K.4    Allen, T.M.5    Yu, X.G.6
  • 15
    • 0035862330 scopus 로고    scopus 로고
    • Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection
    • Altfeld M, Rosenberg ES, Shankarappa R, Mukherjee JS, Hecht FM, Eldridge RL, et al. Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection. J Exp Med 2001, 193:169-180.
    • (2001) J Exp Med , vol.193 , pp. 169-180
    • Altfeld, M.1    Rosenberg, E.S.2    Shankarappa, R.3    Mukherjee, J.S.4    Hecht, F.M.5    Eldridge, R.L.6
  • 16
    • 0036340475 scopus 로고    scopus 로고
    • Clustering patterns of cytotoxic T-lymphocyte epitopes in human immunodeficiency virus type 1 (HIV-1) proteins reveal imprints of immune evasion on HIV-1 global variation
    • Yusim K, Kesmir C, Gaschen B, Addo MM, Altfeld M, Brunak S, et al. Clustering patterns of cytotoxic T-lymphocyte epitopes in human immunodeficiency virus type 1 (HIV-1) proteins reveal imprints of immune evasion on HIV-1 global variation. J Virol 2002, 76:8757-8768.
    • (2002) J Virol , vol.76 , pp. 8757-8768
    • Yusim, K.1    Kesmir, C.2    Gaschen, B.3    Addo, M.M.4    Altfeld, M.5    Brunak, S.6
  • 18
    • 0038205695 scopus 로고    scopus 로고
    • Longitudinal assessment of changes in HIV-specific effector activity in HIV-infected patients starting highly active antiretroviral therapy in primary infection
    • Alter C, Hatzakis C, Tsoukas CM, Pelley K, Rouleau D, LeBlanc R, et al. Longitudinal assessment of changes in HIV-specific effector activity in HIV-infected patients starting highly active antiretroviral therapy in primary infection. J Immunol 2001, 171:477-488.
    • (2001) J Immunol , vol.171 , pp. 477-488
    • Alter, C.1    Hatzakis, C.2    Tsoukas, C.M.3    Pelley, K.4    Rouleau, D.5    LeBlanc, R.6
  • 19
    • 0034724371 scopus 로고    scopus 로고
    • Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8+ and CD4+ T lymphocytes
    • Oxenius A, Price DA, Easterbrook PJ, O'Callaghan CA, Kelleher AD, Whelan JA, et al. Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8+ and CD4+ T lymphocytes. Proc Natl Acad Sci USA 2000, 97:3382-3387.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3382-3387
    • Oxenius, A.1    Price, D.A.2    Easterbrook, P.J.3    O'Callaghan, C.A.4    Kelleher, A.D.5    Whelan, J.A.6
  • 20
    • 0037333799 scopus 로고    scopus 로고
    • Impact of antiretroviral therapy and changes in virus load on human immunodeficiency virus (HIV)-specific T cell responses in primary HIV infection
    • Lacabaratz-Porret C, Urrutia A, Doisne JM, Goujard C, Deveau C, Dalod M, et al. Impact of antiretroviral therapy and changes in virus load on human immunodeficiency virus (HIV)-specific T cell responses in primary HIV infection. J Infect Dis 2003, 187:748-757.
    • (2003) J Infect Dis , vol.187 , pp. 748-757
    • Lacabaratz-Porret, C.1    Urrutia, A.2    Doisne, J.M.3    Goujard, C.4    Deveau, C.5    Dalod, M.6
  • 21
    • 0035862326 scopus 로고    scopus 로고
    • Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection
    • Goulder PJ, Altfeld MA, Rosenberg ES, Nguyen T, Tang Y, Eldridge RL, et al. Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection. J Exp Med 2001, 193:181-194.
    • (2001) J Exp Med , vol.193 , pp. 181-194
    • Goulder, P.J.1    Altfeld, M.A.2    Rosenberg, E.S.3    Nguyen, T.4    Tang, Y.5    Eldridge, R.L.6
  • 22
    • 0037942696 scopus 로고    scopus 로고
    • Comprehensive analysis of human immunodeficiency virus type 1 (HIV-1)-specific gamma interferon-secreting CD8+ T cells in primary HIV-1 infection
    • Cao J, McNevin J, Holte S, Fink L, Corey L, McElrath MJ. Comprehensive analysis of human immunodeficiency virus type 1 (HIV-1)-specific gamma interferon-secreting CD8+ T cells in primary HIV-1 infection. J Virol 2003, 77:6867-6878.
    • (2003) J Virol , vol.77 , pp. 6867-6878
    • Cao, J.1    McNevin, J.2    Holte, S.3    Fink, L.4    Corey, L.5    McElrath, M.J.6
  • 23
    • 0035852758 scopus 로고    scopus 로고
    • The HIV-1 regulatory proteins Tat and Rev are frequently targeted by cytotoxic T lymphocytes derived from HIV-1-infected individuals
    • Addo MM, Altfeld M, Rosenberg ES, Eldridge RL, Philips MN, Habeeb K, et al. The HIV-1 regulatory proteins Tat and Rev are frequently targeted by cytotoxic T lymphocytes derived from HIV-1-infected individuals. Proc Natl Acad Sci USA 2001, 98:1781-1786.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1781-1786
    • Addo, M.M.1    Altfeld, M.2    Rosenberg, E.S.3    Eldridge, R.L.4    Philips, M.N.5    Habeeb, K.6
  • 24
    • 0037302428 scopus 로고    scopus 로고
    • Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load
    • Addo MM, Yu XC, Rathod A, Cohen D, Eldridge RL, Strick D, et al. Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load. J Virol 2003, 77:2081-2092.
    • (2003) J Virol , vol.77 , pp. 2081-2092
    • Addo, M.M.1    Yu, X.C.2    Rathod, A.3    Cohen, D.4    Eldridge, R.L.5    Strick, D.6
  • 25
    • 0037225837 scopus 로고    scopus 로고
    • Association between virus-specific T-cell responses and plasma viral load in human immunodeficiency virus type 1 subtype C infection
    • Novitsky V, Gilbert P, Peter T, McLane MF, Gaolekwe S, Rybak N, et al. Association between virus-specific T-cell responses and plasma viral load in human immunodeficiency virus type 1 subtype C infection. J Virol 2003, 77:882-890.
    • (2003) J Virol , vol.77 , pp. 882-890
    • Novitsky, V.1    Gilbert, P.2    Peter, T.3    McLane, M.F.4    Gaolekwe, S.5    Rybak, N.6
  • 26
    • 10744230046 scopus 로고    scopus 로고
    • T cell responses in HIV type 1-infected adolescent minorities share similar epitope specificities with whites despite significant differences in HLA class I alleles
    • Bansal A, Sabbaj S, Edwards BH, Ritter D, Perkins C, Tang J, et al. T cell responses in HIV type 1-infected adolescent minorities share similar epitope specificities with whites despite significant differences in HLA class I alleles. AIDS Res Hum Retroviruses 2003, 19:1017-1026.
    • (2003) AIDS Res Hum Retroviruses , vol.19 , pp. 1017-1026
    • Bansal, A.1    Sabbaj, S.2    Edwards, B.H.3    Ritter, D.4    Perkins, C.5    Tang, J.6
  • 27
    • 0025853347 scopus 로고
    • Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes
    • Klotman ME, Kim S, Buchbinder A, DeRossi A, Baltimore D, Wong-Staal F. Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes. Proc Natl Acad Sci USA 1991, 88:5011-5015.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5011-5015
    • Klotman, M.E.1    Kim, S.2    Buchbinder, A.3    Derossi, A.4    Baltimore, D.5    Wong-Staal, F.6
  • 28
    • 0024347717 scopus 로고
    • Temporal aspects of DNA and RNA synthesis during human immunodeficiency virus infection: Evidence for differential gene expression
    • Kim SY, Byrn R, Groopman J, Baltimore D. Temporal aspects of DNA and RNA synthesis during human immunodeficiency virus infection: evidence for differential gene expression. J Virol 1989, 63:3708-3713.
    • (1989) J Virol , vol.63 , pp. 3708-3713
    • Kim, S.Y.1    Byrn, R.2    Groopman, J.3    Baltimore, D.4
  • 29
    • 0028252718 scopus 로고
    • Expression kinetics and subcellular localization of HIV-1 regulatory proteins Nef, Tat and Rev in acutely and chronically infected lymphoid cell lines
    • Ranki A, Lagerstedt A, Ovod V, Aavik E, Krohn KJ. Expression kinetics and subcellular localization of HIV-1 regulatory proteins Nef, Tat and Rev in acutely and chronically infected lymphoid cell lines. Arch Virol 1994, 139:365-378.
    • (1994) Arch Virol , vol.139 , pp. 365-378
    • Ranki, A.1    Lagerstedt, A.2    Ovod, V.3    Aavik, E.4    Krohn, K.J.5
  • 30
    • 0032556872 scopus 로고    scopus 로고
    • HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes
    • Collins KL, Chen BK, Kalams SA, Walker BD, Baltimore D. HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes. Nature 1998, 391:397-401.
    • (1998) Nature , vol.391 , pp. 397-401
    • Collins, K.L.1    Chen, B.K.2    Kalams, S.A.3    Walker, B.D.4    Baltimore, D.5
  • 31
    • 0029875421 scopus 로고    scopus 로고
    • Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein
    • Schwartz O, Marechal V, Le Gall S, Lemonnier F, Heard JM. Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein. Nat Med 1996, 2:338-342.
    • (1996) Nat Med , vol.2 , pp. 338-342
    • Schwartz, O.1    Marechal, V.2    Le Gall, S.3    Lemonnier, F.4    Heard, J.M.5
  • 32
    • 0041707676 scopus 로고    scopus 로고
    • Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cytotoxic-T-lymphocyte responses
    • O'Connor DH, Mothe BR, Weinfurter JT, Fuenger S, Rehrauer WM, Jing P, et al. Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cytotoxic-T-lymphocyte responses. J Virol 2003, 77:9029-9040.
    • (2003) J Virol , vol.77 , pp. 9029-9040
    • O'Connor, D.H.1    Mothe, B.R.2    Weinfurter, J.T.3    Fuenger, S.4    Rehrauer, W.M.5    Jing, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.