Synthesis of pyrimidine derivatives possessing an antioxidative property and their inhibitory effects on picryl chloride-induced contact hypersensitivity reaction

Chemical and Pharmaceutical Bulletin

Volumn 51, Issue 12, 2003, Pages 1451-1454

  Isobe, Yoshiaki ^a   Hirota, Kosaku ^b  

^a JAPAN ENERGY CORPORATION   (Japan)

^b GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Antioxidative activity; Barbituric acid; Delayed type hypersensitivity (DTH); di t butylphenol; Uracil

Indexed keywords

6 [2 (3,5 DI TERT BUTYL 4 HYDROXYBENZYLIDENE)HYDRAZINO] 3 METHYL 1 PHENYLURACIL; 6 [2 (4 HYDROXY 3,5 DIMETHOXYBENZYLIDENE)HYDRAZINE] 3 METHYL 1 PHENYLURACIL; 6 [2 (4 HYDROXY 3,5 DIMETHYLBENZYLIDENE)HYDRAZINO] 3 METHYL 1 PHENYLURACIL; BARBITURIC ACID; DIMETHOXYPHENOL; GUAIACOL; OXYGEN; PHENYL GROUP; PICRYL CHLORIDE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG; URACIL; URACIL DERIVATIVE; XYLENOL; ANTIALLERGIC AGENT; ANTIOXIDANT;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; HYPERSENSITIVITY REACTION; INFLAMMATION; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION; ANIMAL; CONTACT DERMATITIS; INSTITUTE FOR CANCER RESEARCH MOUSE; MALE; RAT; SYNTHESIS;

ANIMALS; ANTI-ALLERGIC AGENTS; ANTIOXIDANTS; DERMATITIS, CONTACT; MALE; MICE; MICE, INBRED ICR; PICRYL CHLORIDE; PYRIMIDINES; RATS;

EID: 3142672348     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.51.1451     Document Type: Article

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