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Volumn , Issue 1, 1998, Pages 37-38

Stereoselective syntheses of 2-fluoro-2-methyl-3-hydroxypropionamides by use of a germyl anion species

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EID: 3142669216     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1998-1580     Document Type: Article
Times cited : (11)

References (32)
  • 15
    • 0025123203 scopus 로고
    • 2-Fluoro-2-trifluoromethyl-3-hydroxyalkanamides have already been synthesized in good yield, stereoselectively by a direct aldoltype reaction. See: Kuroboshi, M.; Ishihara, T. Bull. Chem. Soc. Jpn. 1990, 63, 428.
    • (1990) Bull. Chem. Soc. Jpn. , vol.63 , pp. 428
    • Kuroboshi, M.1    Ishihara, T.2
  • 19
    • 26844570156 scopus 로고    scopus 로고
    • note
    • When aldol reactions of N,N-diethyl 2-fluoropropionamide with benzaldehyde by use of LDA or LHMDS were carried out according to the references 2b, 2c, and 4, this product could not be obtained.
  • 29
    • 85085632440 scopus 로고    scopus 로고
    • note
    • 3COOH), respectively. These values agreed with the data of ref. 4g.
  • 30
    • 84988129057 scopus 로고
    • + ion was smaller than that of a Z-enolate (PM3: ΔG=-0.32 kcal/mol, and AM1: ΔG=-1.46 kcal/mol). PM3 method: Stewart, J. J. P. J. Com. Chem. 1989, 10, 209.
    • (1989) J. Com. Chem. , vol.10 , pp. 209
    • Stewart, J.J.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.