Hydroquinone modulates the GM-CSF signaling pathway in TF-1 cells

Leukemia

Volumn 18, Issue 7, 2004, Pages 1296-1304

  Zheng, J H ^a   Pyatt, D W ^a   Gross, S A ^a   Le, A T ^a   Kerzic, P J ^a   Irons, Richard D ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b FUDAN UNIVERSITY   (China)

Author keywords

Activation of ERK; Activator protein 1 (AP 1); Cell proliferation; GM CSF signaling; Hydroquinone (HQ)

Indexed keywords

ALKYLATING AGENT; BENZENE DERIVATIVE; CD34 ANTIGEN; CELL DNA; DRUG METABOLITE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYDROQUINONE; MITOGEN ACTIVATED PROTEIN KINASE; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; TRANSCRIPTION FACTOR AP 1; CARCINOGEN; HYDROQUINONE DERIVATIVE;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; BONE MARROW CELL; CELL PROLIFERATION; COLONY FORMING UNIT; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA BINDING; DRUG CARCINOGENICITY; ENZYME ACTIVATION; ENZYME KINETICS; ENZYME PHOSPHORYLATION; ERYTHROLEUKEMIA; ERYTHROLEUKEMIA CELL; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOSTIMULATION; LEUKEMOGENESIS; PRIORITY JOURNAL; REPORTER GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; BIOSYNTHESIS; CELL DIVISION; CHEMICALLY INDUCED DISORDER; CYTOLOGY; DRUG EFFECT; KINETICS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; TUMOR CELL LINE;

ANTIGENS, CD34; BONE MARROW CELLS; CARCINOGENS; CELL DIVISION; CELL LINE, TUMOR; GRANULOCYTE MACROPHAGE COLONY-STIMULATING FACTORS, RECOMBINANT; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; HYDROQUINONES; KINETICS; LEUKEMIA, ERYTHROBLASTIC, ACUTE; LEUKEMIA, MYELOCYTIC, ACUTE; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1;

EID: 3142666233     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2403389     Document Type: Article

References (28)

1. Sandoval C, Pui C-H, Bowman LC, Heaton D, Hurwitz CA, Raimondi SC et al. Secondary acute myeloid leukemia in children previously treated with alkylating agents, intercalating topoisomerase II inhibitors, and irradiation. J Clin Oncol 1993; 11: 1039-1045.
2. Casciato DA, Scott JL. Acute leukemia following prolonged cytotoxic agent therapy. Medicine 1979; 58: 32-47.
3. Foucar K, McKenna RW, Bloomfield CD, Bowers TK, Brunning RD. Therapy-related leukemia. Cancer 1979; 43: 1285-1296.
4. Irons RD, Stillman WS. Cell proliferation and differentiation in chemical leukemogenesis. Stem Cells 1993; 11: 235-242.
5. Irons RD, Stillman WS, Colagiovanni DB, Henry VA. Synergistic action of the benzene metabolite hydroquinone on myelopoietic stimulating activity of granulocyte/macrophage colony-stimulating factor in vitro. Proc Natl Acad Sci USA 1992; 89: 3691-3695.
6. Irons RD. Effects of the benzene metabolite, hydroquinone, on regulation of differentiation and proliferation of human hematopoietic stem and progenitor cells in vitro. Toxicologist 1997; 36: 105-106.
7. Irons RD, Stillman WS. Impact of benzene metabolites on differentiation of bone marrow progenitor cells. Environ Health Perspect 1996; 104 (Suppl 6): 1247-1250.
8. Irons RD, Stillman WS. The effects of benzene and other leukaemogenic agents on haematopoietic stem and progenitor cell differentiation. Eur J Haematol 1996; 57 (Suppl 60): 119-124.
9. De Groot RP, Coffer PJ, Koenderman L. Regulation of proliferation, differentiation and survival by the IL-3/IL-5/GM-CSF receptor family. Cell Signal 1998; 10: 619-628.
10. Wheadon H, Roberts PJ, Watts MJ, Linch DC. Changes in signal transduction downstream from the granulocyte-macrophage colony-stimulating factor receptor during differentiation of primary hemopoietic cells. Exp Hematol 1999; 27: 1077-1086.
11. Wisdom R. AP-1: one switch for many signals. Exp Cell 1999; 253: 180-185.
12. Platanias LC. Map kinase signaling pathways and hematologic malignancies. Blood 2003; 101: 4667-4679.
13. Esnault S, Malter JS. Extracellular signal-regulated kinase mediates granulocyte-macrophage colony-stimulating factor mesenger RNA stabilization in tumor necrosis factor-α plus fibronectin-activated peripheral blood eosinophils. Blood 2002; 99: 4048-4052.
14. Kim SC, Hahn JS, Min YH, Yoo NC, Ko YW, Lee WJ. Constitutive activation of extracellular signal-regulated kinase in human acute leukemias: combined role of activation of MEK, hyperexpression of extracellular signal-regulated kinase, and downregulation of a phosphatase, PAC1. Blood 1999; 93: 3893-3899.
15. Kitamura T, Tange T, Terasawa T, Chiba S, Kuwaki T, Miyagawa K et al. Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin. J Cell Physiol 1989; 140: 323-334.
16. McCubrey JA, Steelman LS, Hoyle PE, Blalock WL, Weinstein-Oppenheimer C, Franklin RA et al. Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells. Leukemia 1998; 12: 1903-1929.
17. Kolonics A, Apati A, Janossy J, Brozik A, Gati R, Schaefer A et al. Activation of Raf/ERK1/2 MAP kinase pathway is involved in GM-CSF-induced proliferation and survival but not in erythropoietin-induced differentiation of TF-1 cells. Cell Signal 2001; 13: 743-754.
18. Kerzic PJ, Pyatt DW, Zheng JH, Gross SA, Le A, Irons RD. Inhibition of NF-kappaB by hydroquinone sensitizes human bone marrow progenitor cells to TNF-alpha-induced apoptosis. Toxicology 2003; 187: 127-137.
19. + T lymphocytes. Biochem Biophys Res Commun 1996; 227: 380-385.
20. Payne DM, Rossomando AJ, Martino P, Erickson AK, Her JH, Shabanowitz J et al. Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase). EMBO J 1991; 10: 885-892.
21. Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 1995; 270: 27489-27494.
22. Karin M. The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem 1995; 270: 16483-16486.
23. Kinoshita T, Yokota T, Arai K, Miyajima A. Suppression of apoptotic death in hematopoietic cells by signalling through the IL-3/GM-CSF receptors. EMBO J 1995; 14: 266-275.
24. Metcalf D. The granulocyte-macrophage colony-stimulating factors. Science 1985; 229: 16-22.
25. Willman CL, Whittaker MH. The molecular biology of acute myeloid leukemia. Proto-oncogene expression and function in normal and neoplastic myeloid cells. Clin Lab Med 1990; 10: 769-796.
26. Haase D, Fonatsch C. Karyotype and in vitro-response to GM-CSF. Blut 1990; 60: 192-197.
27. Quentmeier H, Dirks WG, Fleckenstein D, Zaborski M, Drexler HG. Tumor necrosis factor-alpha-induced proliferation requires synthesis of granulocyte-macrophage colony-stimulating factor. Exp Hematol 2000; 28: 1008-1015.
28. Finlay GA, Thannickal VJ, Fanburg BL, Paulson KE. Transforming growth factor-beta 1-induced activation of the ERK pathway/activator protein-1 in human lung fibroblasts requires the autocrine induction of basic fibroblast growth factor. J Biol Chem 2000; 275 (36): 27650-27656.