Synthesis of quinazolines and imidazo[1,2-c]quinazolines with the aid of a low-valent titanium reagent

Synlett

Volumn , Issue 6, 2004, Pages 1098-1100

  Shi, Daqing ^a,b,c   Wang, Juxian ^b   Shi, Chunling ^b   Rong, Liangce ^b   Zhuang, Qiya ^a,b   Hu, Hongwen ^c  

^a JIANGSU NORMAL UNIVERSITY   (China)

^b JIANGSU NORMAL UNIVERSITY   (China)

^c NANJING UNIVERSITY   (China)

Author keywords

2 (2 nitrophenyl)imidazole; 2 nitrobenzyl amine; Imidazo 1,2 c quinazoline; Low valent titanium; Quinazoline

Indexed keywords

ALDEHYDE DERIVATIVE; AMINE; ESTER; KETONE DERIVATIVE; QUINOLINE DERIVATIVE; REAGENT; TITANIUM;

ARTICLE; CYCLIZATION; SPECTROSCOPY; SYNTHESIS; X RAY ANALYSIS;

EID: 3142655687     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-822893     Document Type: Article

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18. 4), and the solvent was removed in vacuo to give the crude product to give the pure product 3.
19. 4), and the solvent was removed in vacuo to give the crude product. The crude product was purified by column chromatography on silica gel (200-300 mesh) using petroleum ether (bp 60-90°C)-acetone (5:1) as eluent.
20. 2: C, 82.02; H, 6.02; N, 11.96. Found: C, 82.25; H, 5.89; N, 12.10.
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