Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3

Journal of Biological Chemistry

Volumn 279, Issue 27, 2004, Pages 28789-28797

  Aoyama, Tomoki ^a,b   Okamoto, Takeshi ^a,b   Nagayama, Satoshi ^b   Nishijo, Koichi ^a,b   Ishibe, Tatsuya ^a,b   Yasura, Ko ^a   Nakayama, Tomitaka ^b   Nakamura, Takashi ^b   Toguchida, Junya ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ENZYME INHIBITION; ENZYMES; GENES; TISSUE;

CELL LINES; METHYLATION;

BIOCHEMISTRY;

CHONDROMODULIN I; CYTOSINE; GENE PRODUCT; RNA; SMALL INTERFERING RNA; THYMINE; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CANCER CELL; CARTILAGE CELL; CHM I GENE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DEMETHYLATION; DNA METHYLATION; GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE SEQUENCE; HUMAN; HUMAN CELL; MESENCHYME; NUCLEOTIDE SEQUENCE; OSTEOSARCOMA; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; SEQUENCE ANALYSIS; TRANSCRIPTION REGULATION;

5-METHYLCYTOSINE; AZACITIDINE; BINDING SITES; BLOTTING, WESTERN; BONE AND BONES; CARTILAGE; CELL LINE, TUMOR; CHONDROCYTES; CHROMATIN; CPG ISLANDS; CYTOSINE; DNA METHYLATION; DNA-BINDING PROTEINS; GENES, REPORTER; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LUCIFERASES; MEMBRANE PROTEINS; PRECIPITIN TESTS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; SP1 TRANSCRIPTION FACTOR; SP3 TRANSCRIPTION FACTOR; SULFITES; THYMINE; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 3142652021     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M401273200     Document Type: Article

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