Reproductive and developmental toxicity studies of calcipotriol (MC903) : (1) - A Fertility study in rats by subcutaneous administration

Journal of Toxicological Sciences

Volumn 21, Issue SUPPL. II, 1996, Pages 389-401

  Suzuki, Toshiro ^a   Uchiyama, Hisashi ^a   Koike, Yoshihide ^a   Ono, Masahiro ^b   Shirakawa, Kiyomi ^b   Nagata, Mitsuhiro ^b   Konishi, Ryoji ^b  

^a Yazaki Resources Co   (Japan)

^b Teikoku Seiyaku Co   (Japan)

Author keywords

Anti psoriasic agent; Calcipotriol; Fertility study; MC903; Rats

Indexed keywords

CALCIPOTRIOL; CALCITRIOL; DERMATOLOGICAL AGENT; DRUG DERIVATIVE;

ANIMAL; ARTICLE; BODY WEIGHT; CHEMICALLY INDUCED DISORDER; CORNEA OPACITY; DRUG EFFECT; EATING; FEMALE; FERTILITY; KIDNEY; MALE; ORGAN SIZE; PATHOLOGY; PREGNANCY; PRENATAL DEVELOPMENT; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALS; BODY WEIGHT; CALCITRIOL; CORNEAL OPACITY; DERMATOLOGIC AGENTS; EATING; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; FERTILITY; INJECTIONS, SUBCUTANEOUS; KIDNEY; MALE; ORGAN SIZE; PREGNANCY; RATS;

EID: 3142552467     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.21.supplementii_389     Document Type: Article

References (8)

1. Bindenip, L. and Bramm, E. (1988) : Effects of a novel vitamin D analogue MC903 on cell proliferation and differentiation in vitro and on calcium metabolism in vivo. Biochem. Pharmacol., 37, 889-895.
2. Dawson, A. B. (1926) : A note on the staining of the skeleton of cleared specimens with alizarin red S. Stain Technol., 1, 123-124.
3. Wilson, J. G. (1965) : Methods for administering agents and detecting malformations in experimental animals. "Teratology : Principles and Techniques" (Wilson, J. G. and Warkany, J., eds.), pp.262-277, Univ. of Chicago Press, Chicago.