Coagulation changes and edema formation during long-distance bus travel

Blood Coagulation and Fibrinolysis

Volumn 15, Issue 5, 2004, Pages 419-425

  Schobersberger, Wolfgang ^a,b   Mittermayr, Markus ^c   Innerhofer, Petra ^c   Sumann, Guenther ^c   Schobersberger, Beatrix ^b   Klingler, Anton ^c   Simmer, Markus ^c   Streif, Werner ^c   Fischbach, Uwe ^d   Fries, Dietmar ^c  

^a UNIVERSITY FOR HEALTH SCIENCES   (Austria)

^b Res Inst Leisure and Travel Med   (Austria)

^c UNIVERSITY OF INNSBRUCK   (Austria)

^d UNIVERSITY OF WUPPERTAL   (Germany)

Author keywords

Coagulation; Fibrinolysis; Thrombelastography; Travel thrombosis; Venous thromboembolism

Indexed keywords

ANTITHROMBIN; THROMBIN; TISSUE PLASMINOGEN ACTIVATOR;

ADULT; AIRCRAFT; ARTICLE; BLOOD CLOTTING; CAR; CARDIOVASCULAR RISK; CONTROLLED STUDY; EDEMA; FEMALE; HUMAN; HYPOXIA; MALE; NORMAL HUMAN; PRIORITY JOURNAL; THROMBOELASTOGRAPHY; TRAVEL; VENOUS THROMBOEMBOLISM;

AIRCRAFT; ANOXIA; ANTITHROMBIN III; BLOOD COAGULATION; BLOOD COAGULATION FACTORS; EDEMA; FIBRIN FIBRINOGEN DEGRADATION PRODUCTS; FIBRINOLYSIS; HUMANS; LEG; MOTOR VEHICLES; THROMBELASTOGRAPHY; THROMBOEMBOLISM; TRAVEL;

EID: 3142516201     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mbc.0000114438.81125.cf     Document Type: Article

References (33)

1. Homans J. Thrombosis of deep leg veins due to prolonged sitting. N Engl J Med 1954; 250:148-149.
2. ten Wolde M, Kraaijenhagen RA, Schiereck J, Hagen PJ, Mathijssen JJ, Mac Gillvry MR, et al. Travel and the risk of symptomatic venous thromboembolism. Thromb Haemost 2003; 89:499-505.
3. Scurr JH, Machin SJ, Bailey-King S, Mackie IJ, McDonald S, Coleridge Smith PD. Frequency and prevention of symptomless deep-vein thrombosis in long-haul flights: a randomised trial. Lancet 2001; 357: 1485-1489.
4. Lapostolle F, Surget V, Borron SW, Desmaizieres M, Sordelet D, Lapandry C, et al. Severe pulmonary embolism associated with air travel. N Engl J Med 2001; 345:779-783.
5. Bagshaw M. Traveller's thrombosis: a review of deep venous thrombosis associated with travel. The Air Transport Medicine Committee, Aerospace Medical Association. Aviat Space Environ Med 2001; 72:848-851.
6. Schobersberger W, Hauer B, Sumann G, Gunga H, Partsch H. Traveller's thrombosis: incidence, causes, prevention. Wien Klin Wschr 2002; 114:14-20.
7. Partsch H, Niessner H, Bergau L, Blättler W, Cerny J, Gerlach H, et al. Traveller's Thrombosis 2001. VASA 2001; 31:66-67.
8. Schwarz Th, Siegert G, Oettler W, Halbritter K, Beyer J, Frommhold R, et al. Venous thrombosis after long-haul flights. Arch Intern Med 2003; 163:2759-2764.
9. McQuillan A, Eikelboom JW, Baker RI. Travel-associated venous thrombosis: can we identify those at risk? Blood Coagul Fibrinolysis 2003; 14:671-675.
10. Schobersberger W, Fries D, Mittermayr M, Innerhofer P, Sumann G, Schobersberger B, et al. Changes of biochemical markers and functional tests for clot formation during long-haul flights. Thromb Res 2003; 108:19-24.
11. Gertler JP, Perry L, L'Italien G, Chung-Welch N, Cambria RP, Orkin R, Abott WM. Ambient oxygen tension modulates endothelial fibrinolysis. J Vasc Surg 1993; 18:939-946.
12. Bendz B, Rostrup M, Sevre K, O Andersen T, Sandset PM. Association between acute hypobaric hypoxia and activation of coagulation in human beings. Lancet 2001; 356:657-658.
13. Mannucci PM, Gringeri A, Peyvandi F, Di Paolantonio, Mariani G. Short-term exposure to high altitude causes coagulation activation and inhibits fibrinolysis. Thromb Haemost 2002; 87:342-343.
14. Bärtsch P, Haeberli A, Franciolli M, Kruithof EKO, Straub PW. Coagulation and fibrinolysis in acute mountain sickness and beginning pulmonary edema. J Appl Physiol 1989; 66:2136-2144.
15. Millet J, Vaillot M, Theveniaux J, Brown NL. Experimental venous thrombosis induced by homologous serum in the rat. Thromb Res 1996; 81:497-502.
16. Bärtsch P, Straub PW, Haeberli A. Hypobaric hypoxia. Lancet 2001; 357:955.
17. Crosby A, Talbot NP, Harrison P, Keeling D, Robbins PA. Relation between acute hypoxia and activation of coagulation in human beings. Lancet 2003; 361:2207-2208.
18. Landgraf H, Vanselow B, Schulte-Huermann D, Mülmann MV, Bergau L. Economy class syndrome: rheology, fluid balance, and lower leg edema during a simulated 12-hour long distance flight. Aviat Space Environ Med 1994; 65:930-935.
19. Mittermayr M, Fries D, Innerhofer P, Schobersberger B, Klingler A, Partsch H, et al. Formation of edema and fluid shifts during a long-haul flight. J Travel Med 2003; 10:334-339.
20. Fries D, Innerhofer P, Klingler A, Berresheim U, Mittermayr M, Calatzis A, Schobersberger WI. The effect of the combined administration of colloids and lactated Ringer's solution on the coagulation system: an in vitro study using thrombelastograph coagulation analysis. Anesth Analg 2002; 94:1280-1287.
21. Mallet SV, Cox DJA. Thrombelastography. Br J Anaesth 1992; 62: 307-313.
22. Tardy B, Tardy-Poncet B, Bara L, Laporte-Simitsidis S, Rascle F, Samama MM, et al. Effects of long travels in sitting position in elderly volunteers on biological markers of coagulation activation and fibrinolysis. Thromb Res 1996; 83:153-160.
23. Bendz R, Sevre K, Andersen TO, Sandset PM. Low molecular weight heparin prevents activation of coagulation in a hypobaric environment. Blood Coagul Fibrinolysis 2001; 12:371-374
24. Partsch H. Air travel and deep vein thrombosis-Vienna views. Cardiovasc Surg 2001; 9:147-149.
25. Brundrett G. Comfort and health in commercial aircraft: a literature review. J R Soc Promotion Health 2001; 121:29-37.
26. Hodkinson PD, Hunt BJ, Parmar K, Ernsting J. Is mild normobaric hypoxia a risk factor for venous thromboembolism? J Thromb Haemost 2003; 1:2131-2133.
27. Stricker H, Colucci G, Godio M, Mossi G, Mombelli G. The influence of a prolonged sitting position on the biochemical markers of coagulation activation in healthy subjects: evidence of reduced thrombin generation. J Thromb Haemost 2003; 1:380-399.
28. Bertos-Polo J, Ortega-Carnicer J, Gutierrez-Tirado C, Ambros-Checa A. Pulmonary thromboembolism after long car travel. Eur J Emerg Med 2003; 10:155-156.
29. st century variant of venous thromboembolism associated with immobility. Eur Resp J 2003; 21:374-376.
30. Grimaudo V, Hauert J, Bachmann F, Kruithof EKO. Diurnal variations of the fibrinolytic system. Thromb Haemost 1988; 59:495-499.
31. Krulder JWM, Meyer P, Kluft C. Plasminogen activator inhibitor-1 (PAI-1) antigen, PAI-1 activity and tissue-type plasminogen activator (t-PA) antigen have, in bedridden volunteers, a diurnal rhythm with approximately the same phase and peak late in the morning. Fibrinolysis 1992; 6(suppl):83-84.
32. van Diest R, Hamulyak K, Kop WJ, van Zandvoort C, Appels A. Diurnal variations in coagulation and fibrinolysis in vital exhaustion. Psychosom Med 2002; 64:787-792.
33. Kapiotis S, Jilma B, Quehenberger P, Ruzicka K, Handler S, Speiser W. Morning hypercoagulability and hypofibrinolysis. Diurnal variations in circulating activated factor VII, prothrombin fragment F1 + 2, and plasmin-plasmin inhibitor complex. Circulation 1997; 96:19-21.