Mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3 kinase (PI3K) pathways differently regulate retinal pigment epithelial cell-mediated collagen gel contraction

Experimental Eye Research

Volumn 82, Issue 3, 2006, Pages 529-537

  Bando, Hajime ^a   Ikuno, Yasushi ^a   Hori, Yuichi ^a   Sayanagi, Kaori ^a   Tano, Yasuo ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Collagen gel contraction; Integrin; Mitogen activated protein kinase (MAPK); Phosphatidylinositol 3 kinase (PI3K); Platelet derived growth factor (PDGF); Retinal pigment epithelium (RPE)

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ALPHA1 INTEGRIN; ALPHA2 INTEGRIN; ALPHA3 INTEGRIN; BETA1 INTEGRIN; COLLAGEN GEL; COLLAGEN TYPE 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; NEUTRALIZING ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; RECOMBINANT PLATELET DERIVED GROWTH FACTOR; VISUAL PIGMENT; WORTMANNIN;

ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; FLOW CYTOMETRY; HUMAN; HUMAN CELL; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANTIGENS, CD29; CELL LINE; COLLAGEN; ENZYME INHIBITORS; EXTRACELLULAR MATRIX; FLAVONOIDS; FLOW CYTOMETRY; GELS; HUMANS; INTEGRIN ALPHA1; INTEGRIN ALPHA2; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; PIGMENT EPITHELIUM OF EYE; PLATELET-DERIVED GROWTH FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STIMULATION, CHEMICAL; VITREORETINOPATHY, PROLIFERATIVE;

EID: 31344481036     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2005.08.014     Document Type: Article

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