Imidazo[1,2-a]pyrimidines as functionally selective GABAA ligands

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 5, 2006, Pages 1175-1179

  Blackaby, Wesley P ^a   Atack, John R ^a   Bromidge, Frances ^a   Castro, José L ^a   Goodacre, Simon C ^a   Hallett, David J ^a   Lewis, Richard T ^a   Marshall, George R ^a   Pike, Andrew ^a   Smith, Alison J ^a   Street, Leslie J ^a   Tattersall, David F D ^a   Wafford, Keith A ^a  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

GABAA receptor ligands; Imidazo 1,2 a pyrimidines

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE DERIVATIVE; IMIDAZO[1,2 A]PYRIMIDINE DERIVATIVE;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG BINDING SITE; DRUG CLEARANCE; DRUG EFFECT; DRUG EFFICACY; DRUG INHIBITION; DRUG SELECTIVITY; DRUG STRUCTURE; HUMAN; MOUSE; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION; SUZUKI REACTION;

IMIDAZOLES; LIGANDS; MOLECULAR STRUCTURE; PYRIMIDINES; RECEPTORS, GABA-A; SENSITIVITY AND SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 31344474360     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.11.112     Document Type: Article

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