Identification and determination of major flavonoids in rat urine by HPLC-UV and HPLC-MS methods following oral administration of Dalbergia odorifera extract

Biomedical Chromatography

Volumn 20, Issue 1, 2006, Pages 101-108

  Liu, Rongxia ^a,b   Wang, Wei ^a   Wang, Qiao ^a,b   Bi, Kaishun ^b   Guo, Dean ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

(3R) 4 methoxy 2 ,3,7 trihydroxyisoflavanone; Dalbergia odorifera; Flavonoids; Urine; Vestitone

Indexed keywords

BODY FLUIDS; RATS;

(3R)-4′-METHOXY-2′,3,7-TRIHYDROXYISOFLAVANONE; DALBERGIA ODORIFERA; FLAVONOID; HPLC-MS; HPLC-UV/MS; METHOXY; ORAL ADMINISTRATION; RAT URINE; URINE; VESTITONE;

FLAVONOIDS;

2' HYDROXYFORMONONETIN; 2',7 DIHYDROXY 4',5' DIMETHOXYISOFLAVONE; 3' HYDROXYDAIDZEIN; 3' HYDROXYMELANETTIN; 3' O METHYLVIOLANONE; 4 METHOXYDALBERGIONE; 4' METHOXY 2',3,7 TRIHYDROXYISOFLAVANONE; BUTEIN; BUTIN; CHALCONE; DALBERGIA ODORIFERA EXTRACT; DALBERGIN; FLAVONOID; FORMONONETIN; ISOFLAVONE; ISOLIQUIRITIGENIN; KOPARIN; LIQUIRITIGENIN; MEDICARPIN; MELANETTIN; PINOCEMBRINE; PLANT EXTRACT; PRUNETIN; PTEROCARPAN DERIVATIVE; SATIVANONE; STEVENIN; UNCLASSIFIED DRUG; VESTITONE; VIOLANONE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DALBERGIA; DALBERGIA ODORIFERA; DRUG ABSORPTION; DRUG EXCRETION; DRUG STRUCTURE; DRUG URINE LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NONHUMAN; RAT; SEPARATION TECHNIQUE; ULTRAVIOLET SPECTROSCOPY; URINALYSIS; URINARY EXCRETION; VALIDATION PROCESS;

ANIMALIA; DALBERGIA; DALBERGIA ODORIFERA;

EID: 31344440825     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.535     Document Type: Article

References (16)

1. Anagnostopoulou MA, Kefalas P, Kokkalou E, Assimopoulou AN and Papageorgiou VP. Analysis of antioxidant compounds in sweet orange peel by HPLC-diode array detection-electrospray ionization mass spectrometry. Biomedical Chromatography 2005; 19: 138-148.
2. Cai H, Verschoyle RD, Steward WP and Gescher AJ. Determination of the flavone tricin in human plasma by high-performance liquid chromatography. Biomedical Chromatography 2003; 17: 435-439.
3. Chan SC, Chang YS and Kuo SC. Neoflavonoids from Dalbergia odorifera. Phytochemistry 1997; 46: 947-949.
4. Chan SC, Chang YS, Wang JP, Chen SC and Kuo SC. Three new flavonoids and antiallergic, anti-inflammatory constituents from the heartwood of Dalbergia odorifera. Planta Medica 1998; 64: 153-158.
5. Cheng ZJ, Kuo SC, Chan SC, Ko FN and Teng CM. Antioxidant properties of butein isolated from Dalbergia odorifera. Biochimica Biophysica Acta. 1998; 1392: 291-299.
6. Goda Y, Kiuchi F, Shibuya M and Sankawa U. Inhibitors of prostaglandin biosynthesis from Dalbergia odorifera. Chemical Pharmaceutical Bulletin 1992; 40: 2452-2457.
7. He XG. On-line identification of phytochemical constituents in botanical extracts by combined high-performance liquid chromatographic-diode array detection-mass spectrometric techniques. Journal of Chromatography A 2000; 880: 203-232.
8. Huck CW, Buchmeiser MR and Bonn GK. Fast analysis of flavonoids in plant extracts by liquid chromatography-ultraviolet absorbance detection on poly (carboxylic acid)-coated silica and electrospray ionization tandem mass spectrometric detection. Journal of Chromatography A 2001; 943: 33-38.
9. Kanaze FI, Bounartzi MI and Niopas I. A validated HPLC determination of the flavone aglycone diosmetin in human plasma. Biomedical Chromatography 2004; 18: 800-804.
10. Pharmacopoeia Commission of PRC. Pharmacopoeia of the People's Republic of China, Vol. 1. Chemical Industry Press: Beijing, 2000; 184-185.
11. Rebecca W, Kayser O, Hagels H, Zessin KH, Madundo M and Gamba N. The phytochemical profile and identification of main phenolic compounds from the leaf exudates of Aloe secundiflora by high-performance liquid chromatography-mass spectroscopy. Phytochemical Analysis 2003; 14: 83-86.
12. Wang W, Weng XC and Cheng DL. Antioxidant activities of natural phenolic components from Dalbergia odorifera T. Chen [J]. Food Chemistry 2000; 71: 45-49.
13. Williams CA and Harborne JB. Plant phenolics. In Methods in Plant Biochemistry, Dey PM and Harborne JB (eds). Academic Press: London, 1989; 421.
14. Xiao HB, Krucker M, Albert K and Liang XM. Determination and identification of isoflavonoids in Radix astragali by matrix solid-phase dispersion extraction and high-performance liquid chromatography with photodiode array and mass spectrometric detection. Journal of Chromatography A 2004; 1032: 117-124.
15. Xie ZW. A Collection of China Traditional and Herbal Medicine. People's Press of Health: Beijing, 1996; 442.
16. Yu SM, Cheng ZJ and Kuo SC. Endothelium-dependent relaxation of rat aorta by butein, a novel cyclic AMP-specific phosphodiesterase inhibitor. European Journal of Pharmacology 1995; 280: 69-77.