The level of endothelin-1 and nitric oxide in patients with chronic viral hepatitis B and C and correlation with histopathological grading and staging

Hepatology Research

Volumn 34, Issue 2, 2006, Pages 111-116

  Ersoy, Yasemin ^a   Bayraktar, Nihayet Mehmet ^a   Mizrak, Bulent ^a   Ozerol, Ibrahim Halil ^a   Gunal, Selami ^a   Aladag, Murat ^a   Bayindir, Yasar ^a  

^a INONU UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

Author keywords

Chronic hepatitis B; Chronic hepatitis C; Endothelin 1; Hepatic necroinflammation; Histopathological grading and staging; Nitric oxide

Indexed keywords

ALANINE AMINOTRANSFERASE; ENDOTHELIN 1; HEPATITIS B SURFACE ANTIGEN; NITRIC OXIDE; NITRITE;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CHRONIC HEPATITIS; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE CLASSIFICATION; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEPATITIS B; HEPATITIS C; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LINEAR REGRESSION ANALYSIS; LIVER BIOPSY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; STATISTICAL SIGNIFICANCE;

EID: 31344434702     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hepres.2005.11.005     Document Type: Article

References (36)

1. M. Yanagisawa H. Kurihara S. Kimura et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells Nature 332 6163 1988 411-415
2. H. Ehrenreich R.W. Anderson C.H. et al. Fox Endothelins, peptides with potent vasoactive properties, are produced by human macrophages J Exp Med 172 6 1990 1741-1748
3. W. Koda K. Harada K. et al. Tsuneyama Evidence of the participation of peribiliary mast cells in regulation of the peribiliary vascular plexus along the intrahepatic biliary tree Lab Invest 80 7 2000 1007-1017
4. M. Bauer J.X. Zhang I. Bauer M.G. Clemens ET-1 induced alterations of hepatic microcirculation: Sinusoidal and extrasinusoidal sites of action Am J Physiol 267 1 Pt 1 1994 G143-G149
5. D.C. Rockey Hepatic blood flow regulation by stellate cells in normal and injured liver Semin Liver Dis 21 3 2001 337-349
6. G. Notas C. Xidakis V. Valatas A. Kouroumalis E. Kouroumalis Levels of circulating endothelin-1 and nitrates/nitrites in patients with virus-related hepatocellular carcinoma J Viral Hepat 8 1 2001 63-69
7. K.S. Christopherson D.S. Bredt Nitric oxide in excitable tissues: physiological roles and disease J Clin Invest 100 10 1997 2424-2429
8. R.M. Clancy A.R. Amin S.B. Abramson The role of nitric oxide in inflammation and immunity Arthritis Rheum 41 7 1998 1141-1151
9. P.L. Majano C. Garcia-Monzon M. Lopez-Cabrera et al. Inducible nitric oxide synthase expression in chronic viral hepatitis. Evidence for a virus-induced gene upregulation J Clin Invest 101 7 1998 1343-1352
10. M.M. Abdel Rahman H. el Gammal G. Nasr M.A. Arafa O. Nassar A.M. Shaheen Radio-immuno assay estimation of plasma endothelin levels in patients with bilharzial and post viral liver cirrhosis: A possible new additive factor in aggravation of portal hypertension J Egypt Soc Parasitol 25 2 1995 311-320
11. M. Kitano J. Uemasu H. Kawasaki Increased urinary endothelin excretion in patients with liver cirrhosis J Gastroenterol Hepatol 11 4 1996 347-352
12. J.S. Lin Y.Q. Cheng J.Z. Liao K.H. Liang P. Xiong Correlation between polymorphism of TaqI of ET-1 gene and cirrhotic portal hypertension Zhonghua Yi Xue Za Zhi 83 6 2003 463-466
13. M. Uchihara N. Izumi C. Sato F. Marumo Clinical significance of elevated plasma endothelin concentration in patients with cirrhosis Hepatology 16 1 1992 95-99
14. H. Matsumoto J. Uemasu M. Kitano H. Kawasaki Clinical significance of plasma endothelin-1 in patients with chronic liver disease Dig Dis Sci 39 12 1994 2665-2670
15. Q. Tong L. Zeng Study on the correlation of plasma NO, ET-1 and ALT in the patients with chronic hepatitis and cirrhosis J Tongji Med Univ 20 3 2000 203-204
16. Y. Uchida M. Watanabe Plasma endothelin-1 concentrations are elevated in acute hepatitis and liver cirrhosis but not in chronic hepatitis Gastroenterol Jpn 28 5 1993 666-672
17. R. de Franchis A. Hadengue G. Lau et al. EASL International Consensus Conference on Hepatitis B 13-14 September 2002, Geneva, Switzerland J Hepatol 39 Suppl. 1 2003 S3-S25
18. K. Ishak A. Baptista L. Bianchi et al. Histological grading and staging of chronic hepatitis J Hepatol 22 6 1995 696-699
19. L.C. Green D.A. Wagner J. Glogowski P.L. Skipper J.S. Wishnok S.R. Tannenbaum Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids Anal Biochem 126 1 1982 131-138
20. P.N. Bories C. Bories Nitrate determination in biological fluids by an enzymatic one-step assay with nitrate reductase Clin Chem 41 6 Pt 1 1995 904-907
21. D.C. Rockey L. Fouassier J.J. Chung et al. Cellular localization of endothelin-1 and increased production in liver injury in the rat: potential for autocrine and paracrine effects on stellate cells Hepatology 27 2 1998 472-480
22. P.S. Kamath H.A. Carpenter R.V. Lloyd et al. Hepatic localization of endothelin-1 in patients with idiopathic portal hypertension and cirrhosis of the liver Liver Transpl 6 5 2000 596-602
23. I. Alam N.M. Bass P. Bacchetti L. Gee D.C. Rockey Hepatic tissue endothelin-1 levels in chronic liver disease correlate with disease severity and ascites Am J Gastroenterol 95 1 2000 199-203
24. M. Sugiura T. Inagami V. Kon Endotoxin stimulates endothelin-release in vivo and in vitro as determined by radioimmunoassay Biochem Biophys Res Commun 161 3 1989 1220-1227
25. J. Hao J. Shi W. Ren et al. Hepatic microcirculatory disturbances in patients with chronic hepatitis B Chin Med J (Engl) 115 1 2002 65-68
26. M. Paxian S.A. Keller R. Baveja K. Korneszczuk T.T. Huynh M.G. Clemens Functional link between ETB receptors and eNOS maintain tissue oxygenation in the normal liver Microcirculation 11 5 2004 435-449
27. Z. Kmiec Cooperation of liver cells in health and disease Adv Anat Embryol Cell Biol 161 III-VIII 2001 1-151
28. J. Hao J. Shi W. Ren et al. Hepatic microcirculatory disturbances in patients with chronic hepatitis B Chin Med J (Engl) 115 1 2002 65-68
29. E.R. Levin Endothelins N Engl J Med 333 6 1995 356-363
30. H. Yokomori M. Oda H. Ishii Improvement of overexpression of endothelin B receptor in human cirrhotic liver by interferon therapy J Gastroenterol 38 7 2003 707-709
31. A. Hokari M. Zeniya H. Esumi T. Ishikawa Y. Kurasima G. Toda Role of nitric oxide (NO) in interferon-alpha therapy for hepatitis C J Infect 51 1 2005 47-53
32. G. Lake-Bakaar D. Sorbi V. Mazzoccoli Nitric oxide and chronic HCV and HIV infections Dig Dis Sci 46 5 2001 1072-1076
33. M.J. Amaro J. Bartolome M. Pardo T. Cotonat F. Lopez V. Carreno Decreased nitric oxide production in chronic viral hepatitis B and C J Med Virol 51 4 1997 326-331
34. O. Kandemir A. Polat A. Kaya Inducible nitric oxide synthase expression in chronic viral hepatitis and its relation with histological severity of disease J Viral Hepat 9 6 2002 419-423
35. J. Liu M.P. Waalkes Nitric oxide and chemically induced hepatotoxicity: beneficial effects of the liver-selective nitric oxide donor, V-PYRRO/NO Toxicology 208 2 2005 289-297
36. Wang K, Han LY, Lu Q, Wang B, Li XH, Wang HM. Nitric oxide and nitric oxide synthase in patients with chronic hepatitis B. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2005 19 2 142-5