Excessive portal flow causes graft failure in extremely small-fo-size liver transplantation in pigs

World Journal of Gastroenterology

Volumn 11, Issue 44, 2005, Pages 6954-6959

  Wang, Hong Sheng ^a   Ohkohchi, Nobuhiro ^b   Enomoto, Yoshitaka ^a   Usuda, Masahiro ^a   Miyagi, Shigehito ^a   Asakura, Takeshi ^a   Masuoka, Hiroo ^a   Aiso, Takashi ^a   Fukushima, Keisuke ^a   Narita, Tomohiro ^a   Yamaya, Hideyuki ^a   Nakamura, Atsushi ^a   Sekiguchi, Satoshi ^a   Kawagishi, Naoki ^a   Sato, Akira ^a   Satomi, Susumu ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Hyperperfusion syndrome; Liver regeneration; Portocaval shunt; Postoperative liver dysfunction; Sinusoidal microcirculatory injury; Small for size liver transplantation

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY BLOOD FLOW; ARTICLE; CONTROLLED STUDY; DEATH; GRAFT FAILURE; HISTOPATHOLOGY; LIVER BLOOD FLOW; LIVER DYSFUNCTION; LIVER SIZE; LIVER TRANSPLANTATION; MICROANGIOPATHY; NONHUMAN; POSTOPERATIVE COMPLICATION; SURGICAL TECHNIQUE; SURVIVAL RATE; SWINE;

EID: 31144441949     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i44.6954     Document Type: Article

References (25)

1. Strong RW, Lynch SV, Ong TH, Matsunami H, Koido Y, Balderson GA. Successful liver transplantation from a living donor to her son. N Engl J Med 1990; 322: 1505-1507
2. Hashikura Y, Makuuchi M, Kawasaki S, Matsunami H, Ikegami T, Nakazawa Y, Kiyosawa K, Ichida T. Successful living-related partial liver transplantation to an adult patient. Lancet 1994; 343: 1233-1234
3. Testa G, Malago M, Broelsch CE. Living-donor liver transplantation in adults. Langenbecks Arch Surg 1999; 384: 536-543
4. Ito T, Kiuchi T, Yamamoto H, Oike F, Ogura Y, Fujimoto Y, Hirohashi K, Tanaka AK. Changes in portal venous pressure in the early phase after living donor liver transplantation: pathogenesis and clinical implications. Transplantation 2003; 75: 1313-1317
5. Garcia Valdecasas JC, Fuster J, Charco R, Bombuy E, Fondevila C, Navasa M, Rodriguez-Laiz G, Ferrer J, Amador MA, Llovet JM, Forns X, Rimola A. Adult living donor liver transplantation. Analysis of the first 30 cases. Gastroenterol Hepatol 2003; 26: 525-530
6. Kawasaki S, Makuuchi M, Matsunami H, Hashikura Y, Ikegami T, Nakazawa Y, Chisuwa H, Terada M, Miyagawa S. Living related liver transplantation in adults. Ann Surg 1998; 227: 269-274
7. Fan ST, Lo CM, Liu CL. Technical refinement in adult-to-adult living donor liver transplantation using right lobe graft. Ann Surg 2000; 231: 126-131
8. Sugawara Y, Makuuchi M. Small-for-size graft problems in adult-to-adult living-donor liver transplantation. Transplantation 2003; 75: S20-22
9. Emond JC, Renz JF, Ferrell LD, Rosenthal P, Lim RC, Roberts JP, Lake JR, Ascher NL. Functional analysis of grafts from living donors. Implications for the treatment of older recipients. Ann Surg 1996; 224: 544-52; discussion 552-554
10. Nishizaki T, Ikegami T, Hiroshige S, Hashimoto K, Uchiyama H, Yoshizumi T, Kishikawa K, Shimada M, Sugimachi K. Small graft for living donor liver transplantation. Ann Surg 2001; 233: 575-580
11. Kiuchi T, Kasahara M, Uryuhara K, Inomata Y, Uemoto S, Asonuma K, Egawa H, Fujita S, Hayashi M, Tanaka K. Impact of graft size mismatching on graft prognosis in liver transplantation from living donors. Transplantation 1999; 67: 321-327
12. Lo CM, Fan ST, Chan JK, Wei W, Lo RJ, Lai CL. Minimum graft volume for successful adult-to-adult living donor liver transplantation for fulminant hepatic failure. Transplantation 1996; 62: 696-698
13. Kelly DM, Demetris AJ, Fung JJ, Marcos A, Zhu Y, Subbotin V, Yin L, Totsuka E, Ishii T, Lee MC, Gutierrez J, Costa G, Venkataraman R, Madariaga JR. Porcine partial liver transplantation: a novel model of the "small-for-size" liver graft. Liver Transpl 2004; 10: 253-263
14. Asakura T, Ohkohchi N, Orii T, Koyamada N, Tsukamoto S, Sato M, Enomoto Y, Usuda M, Satomi S. Portal vein pressure is the key for successful liver transplantation of an extremely small graft in the pig model. Transpl Int 2003; 16: 376-382
15. Yanaga K, Kishikawa K, Suehiro T, Nishizaki T, Shimada M, Itasaka H, Nomoto K, Kakizoe S, Sugimachi K. Partial hepatic grafting: porcine study on critical volume reduction. Surgery 1995; 118: 486-492
16. Starzl TE, Putnam CW, Groth CG, Corman JL, Taubman J. Alopecia, ascites, and incomplete regeneration after 85 to 90 per cent liver resection. Am J Surg 1975; 129: 587-590
17. Kahn D, Hickman R, Terblanche J, von Sommoggy S. Partial hepatectomy and liver regeneration in pigs-the response to different resection sizes. J Surg Res 1988; 45: 176-180
18. Nagao M, Isaji S, Iwata M, Kawarada Y. The remnant liver dysfunction after 84% hepatectomy in dogs. Hepatogastroenterology 2000; 47: 1564-1569
19. Panis Y, McMullan DM, Emond JC. Progressive necrosis after hepatectomy and the pathophysiology of liver failure after massive resection. Surgery 1997; 121: 142-149
20. Garcia-Valdecasas JC, Fuster J, Charco R, Bombuy E, Fondevila C, Ferrer J, Ayuso C, Taura P. Changes in portal vein flow after adult living-donor liver transplantation: does it influence postoperative liver function? Liver Transpl 2003; 9: 564-569
21. Smyrniotis V, Kostopanagiotou G, Kondi A, Gamaletsos E, Theodoraki K, Kehagias D, Mystakidou K, Contis J. Hemodynamic interaction between portal vein and hepatic artery flow in small-for-size split liver transplantation. Transpl Int 2002; 15: 355-360
22. Ayata G, Pomfret E, Pomposelli JJ, Gordon FD, Lewis WD, Jenkins RL, Khettry U. Adult-to-adult live donor liver transplantation: a short-term clinicopathologic study. Hum Pathol 2001; 32: 814-822
23. Boillot O, Delafosse B, Mechet I, Boucaud C, Pouyet M. Small-for-size partial liver graft in an adult recipient; a new transplant technique. Lancet 2002; 359: 406-407
24. Man K, Lo CM, Ng IO, Wong YC, Qin LF, Fan ST, Wong J. Liver transplantation in rats using small-for-size grafts: a study of hemodynamic and morphological changes. Arch Surg 2001; 136: 280-285
25. Sato Y, Koyama S, Tsukada K, Hatakeyama K. Acute portal hypertension reflecting shear stress as a trigger of liver regeneration following partial hepatectomy. Surg Today 1997; 27: 518-526