Characteristics of hepatitis B virus in Ghana: Full length genome sequences indicate the endemicity of genotype E in West Africa

Journal of Medical Virology

Volumn 78, Issue 2, 2006, Pages 178-184

  Huy, Tran Thien Tuen ^a,b   Ishikawa, Koichi ^a,d   Ampofo, William ^d   Izumi, Taku ^a   Nakajima, Akira ^a   Ansah, Justina ^c   Tetteh, John O ^c   Nii Trebi, Nicholas ^d   Aidoo, Simeon ^d   Ofori Adjei, David ^d   Sata, Tetsutaro ^a   Ushijima, Hiroshi ^b   Abe, Kenji ^a  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c National Blood Service   (Ghana)

^d University of Ghana   (Ghana)

Author keywords

Escape mutant; Full length genome; Genotype E; Ghana; Hepatitis B virus

Indexed keywords

VIRUS DNA;

AFRICA; ARTICLE; BLOOD ANALYSIS; BLOOD DONOR; CLINICAL FEATURE; GENE ISOLATION; GENE SEQUENCE; GENETIC VARIABILITY; GENOTYPE; GEOGRAPHIC DISTRIBUTION; GHANA; HEPATITIS B VIRUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; STRAIN DIFFERENCE; UNINDEXED SEQUENCE; VACCINATION; VIRUS GENE; VIRUS GENOME; VIRUS MUTANT; VIRUS S GENE; VIRUS STRAIN;

AMINO ACID SEQUENCE; BLOOD DONORS; GENES, VIRAL; GENOME, VIRAL; GHANA; HEPATITIS B; HEPATITIS B VIRUS; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY; VARIATION (GENETICS); VIRAL ENVELOPE PROTEINS;

DNA VIRUSES; HEPATITIS B VIRUS;

EID: 31144433111     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.20525     Document Type: Article

References (30)

1. Arauz-Ruiz P, Norder H, Robertson BH, Magnius LO. 2002. Genotype H: A new Amerindian genotype of hepatitis B virus revealed in Central America. J Gen Virol 83:2059-2073.
2. Dumpis U, Mendy M, Hill A, Thursz M, Hall A, Whittle H, Karayiannis P. 2001. Prevalence of HBV core promoter/precore/core mutations in Gambian chronic carriers. J Med Virol 65:664-670.
3. Gerlich WH. 2004. Diagnostic problems caused by HBsAg mutants-a consensus report of an expert meeting. Intervirology 47:310-313.
4. Grethe S, Monazahian M, Bohme I, Thomssen R. 1998. Characterization of unusual escape variants of hepatitis B virus isolated from a hepatitis B surface antigen-negative subject. J Virol 72:7692-7696.
5. Gunther S, Li BC, Miska S, Kruger DH, Meisel H, Will H. 1995. A novel method for efficient amplification of whole hepatitis B virus genomes permits rapid functional analysis and reveals deletion mutants in immunosuppressed patients. J Virol 69:5437-5444.
6. Hsu HY, Chang MH, Ni YH, Lin HH, Wang SM, Chen DS. 1997. Surface gene mutants of hepatitis B virus in infants who develop acute or chronic infections despite immunoprophylaxis. Hepatology 26: 786-791.
7. Hsu HY, Chang MH, Liaw SH, Ni YH, Chen HL. 1999. Changes of hepatitis B surface antigen variants in carrier children before and after universal vaccination in Taiwan. Hepatology 30:1312-1317.
8. Huy TT, Ushijima H, Win KM, Luengrojanakul P, Shrestha PK, Zhong ZH, Smirnov AV, Taltavull TC, Sata T, Abe K. 2003. High prevalence of hepatitis B virus pre-s mutant in countries where it is endemic and its relationship with genotype and chronicity. J Clin Microbiol 41:5449-5455.
9. Huy TT, Ushijima H, Quang VX, Win KM, Luengrojanakul P, Kikuchi K, Sata T, Abe K. 2004. Genotype C of hepatitis B virus can be classified into at least two subgroups. J Gen Virol 85:283-292.
10. Kao JH, Chen PJ, Lai MY, Chen DS. 2000. Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B. Gastroenterology 118:554-559.
11. Kew MC. 1996. Progress towards the comprehensive control of hepatitis B in Africa: A view from South Africa. Gut 38:S31-S36.
12. Kramvis A, Kew M, Francois G. 2005a. Hepatitis B virus genotypes. Vaccine 23:2409-2423.
13. Kramvis A, Restorp K, Norder H, Botha JF, Magnius LO, Kew MC. 2005b. Full genome analysis of hepatitis B virus genotype E strains from South-Western Africa and Madagascar reveals low genetic variability. J Med Virol 77:47-52.
14. Kumar S, Tamura K, Nei M. 2004. MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment. Brief Bioinform 5:150-163.
15. Laskus T, Radkowski M, Nowicki M, Wang LF, Vargas H, Rakela J. 1998. Association between hepatitis B virus core promoter rearrangements and hepatocellular carcinoma. Biochem Biophys Res Commun 244:812-814.
16. Lee WM. 1997. Hepatitis B virus infection. N Engl J Med 337:1733-1745.
17. Magnius LO, Norder H. 1995. Subtypes, genotypes and molecular epidemiology of the hepatitis B virus as reflected by sequence variability of the S-gene. Intervirology 38:24-34.
18. Martinson FE, Weigle KA, Mushahwar IK, Weber DJ, Royce R, Lemon SM. 1996. Seroepidemiological survey of hepatitis B and C virus infections in Ghanaian children. J Med Virol 48:278-283.
19. Mulders MN, Venard V, Njayou M, Edorh AP, Bola Oyefolu AO, Kehinde MO, Muyembe Tamfum JJ, Nebie YK, Maiga I, Ammerlaan W, Fack F, Omilabu SA, Le Faou A, Muller CP. 2004. Low genetic diversity despite hyperendemicity of hepatitis B virus genotype E throughout West Africa. J Infect Dis 190:400-408.
20. Norder H, Courouce AM, Magnius LO. 1992. Molecular basis of hepatitis B virus serotype variations within the four major subtypes. J Gen Virol 73:3141-3145.
21. Norder H, Courouce AM, Magnius LO. 1994. Complete genomes, phylogenetic relatedness, and structural proteins of six strains of the hepatitis B virus, four of which represent two new genotypes. Virology 198:489-503.
22. Odemuyiwa SO, Mulders MN, Oyedele OI, Ola SO, Odaibo GN, Olaleye DO, Muller CP. 2001. Phylogenetic analysis of new hepatitis B virus isolates from Nigeria supports endemicity of genotype E in West Africa. J Med Virol 65:463-469.
23. Okamoto H, Tsuda F, Sakugawa H, Sastrosoewignjo RI, Imai M, Miyakawa Y, Mayumi M. 1988. Typing hepatitis B virus by homology in nucleotide sequence: Comparison of surface antigen subtypes. J Gen Virol 69:2575-2583.
24. Oon CJ, Lim GK, Ye Z, Goh KT, Tan KL, Yo SL, Hopes E, Harrison TJ, Zuckerman AJ. 1995. Molecular epidemiology of hepatitis B virus vaccine variants in Singapore. Vaccine 13:699-702.
25. Saitou N, Nei M. 1987. The neighbor-joining method: A new method for reconstructing phylogenetic trees. Mol Biol Evol 4:406-425.
26. Sarkodie F, Adarkwa M, Adu-Sarkodie Y, Candotti D, Acheampong JW, Allain JP. 2001. Screening for viral markers in volunteer and replacement blood donors in West Africa. Vox Sang 80:142-147.
27. Stuyver L, De Gendt S, Van Geyt C, Zoulim F, Fried M, Schinazi RF, Rossau R. 2000. A new genotype of hepatitis B virus: Complete genome and phylogenetic relatedness. J Gen Virol 81:67-74.
28. Suzuki S, Sugauchi F, Orito E, Kato H, Usuda S, Siransy L, Arita I, Sakamoto Y, Yoshihara N, El-Gohary A, Ueda R, Mizokami M. 2003. Distribution of hepatitis B virus (HBV) genotypes among HBV carriers in the Cote d'Ivoire: Complete genome sequence and phylogenetic relatedness of HBV genotype E. J Med Virol 69:459-465.
29. Takahashi K, Brotman B, Usuda S, Mishiro S, Prince AM. 2000. Full-genome sequence analyses of hepatitis B virus (HBV) strains recovered from chimpanzees infected in the wild: Implications for an origin of HBV. Virology 267:58-64.
30. Thakur V, Kazim SN, Guptan RC, Hasnain SE, Bartholomeusz A, Malhotra V, Sarin SK. 2005. Transmission of G145R mutant of HBV to an unrelated contact. J Med Virol 76:40-46.