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Volumn 45, Issue 1, 2006, Pages 38-46

Age dependent phosphorylation and deregulation of p53 in human vestibular schwannomas

Author keywords

Human vestibular schwannomas; LOH; p53 mrna; p53 protein; Ser 392 phosphorylation

Indexed keywords

MESSENGER RNA; PROTEIN P53; SERINE;

EID: 31044432520     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20150     Document Type: Article
Times cited : (14)

References (46)
  • 1
    • 0023854155 scopus 로고
    • Neurofibromatosis 2 (bilateral acoustic neurofibromatosis)
    • Martuza RL, Eldridge R. Neurofibromatosis 2 (bilateral acoustic neurofibromatosis). N Engl J Med 1988;318:684-688.
    • (1988) N Engl J Med , vol.318 , pp. 684-688
    • Martuza, R.L.1    Eldridge, R.2
  • 2
    • 0025797408 scopus 로고
    • Bilateral cerebellopontine angle tumors in neurofibromatosis type 2
    • Baldwin D, King TT, Chevretton E, Morrison AW. Bilateral cerebellopontine angle tumors in neurofibromatosis type 2. J Neurosurg 1991;74:910-915.
    • (1991) J Neurosurg , vol.74 , pp. 910-915
    • Baldwin, D.1    King, T.T.2    Chevretton, E.3    Morrison, A.W.4
  • 3
    • 0027245423 scopus 로고
    • Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2
    • Rouleau GA, Merel P, Lutchman M, et al. Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2. Nature 1993;363:515-521.
    • (1993) Nature , vol.363 , pp. 515-521
    • Rouleau, G.A.1    Merel, P.2    Lutchman, M.3
  • 4
    • 0027405720 scopus 로고
    • A novel meosine-, ezrin-, radixin-like gene is candidate for the neurofibromatosis 2 tumor suppressor
    • Trofatter JA, MacCollin MM, Rutter JL, et al. A novel meosine-, ezrin-, radixin-like gene is candidate for the neurofibromatosis 2 tumor suppressor. Cell 1993;72:791-800.
    • (1993) Cell , vol.72 , pp. 791-800
    • Trofatter, J.A.1    MacCollin, M.M.2    Rutter, J.L.3
  • 5
    • 0023261211 scopus 로고
    • Clonal analysis of human colorectal tumors
    • Fearon ER, Hamilton SR, Vogelstein B. Clonal analysis of human colorectal tumors. Science 1987;238:193-197.
    • (1987) Science , vol.238 , pp. 193-197
    • Fearon, E.R.1    Hamilton, S.R.2    Vogelstein, B.3
  • 7
    • 0024387728 scopus 로고
    • Mutations in the p53 gene occur in diverse human tumour types
    • Nigro JM, Baker SJ, Preisinger AC, et al. Mutations in the p53 gene occur in diverse human tumour types. Nature 1989;342:705-708.
    • (1989) Nature , vol.342 , pp. 705-708
    • Nigro, J.M.1    Baker, S.J.2    Preisinger, A.C.3
  • 8
    • 0028845158 scopus 로고
    • Small peptides activate the latent sequence-specific DNA binding function of p53
    • Hupp TR, Sparks A, Lane DP. Small peptides activate the latent sequence-specific DNA binding function of p53. Cell 1995;83:237-245.
    • (1995) Cell , vol.83 , pp. 237-245
    • Hupp, T.R.1    Sparks, A.2    Lane, D.P.3
  • 9
    • 3142685265 scopus 로고    scopus 로고
    • Ser 392 phosphorylation regulates the oncogenic function of mutant p53
    • Yap DB, Hsieh JK, Zhong S, et al. Ser 392 phosphorylation regulates the oncogenic function of mutant p53. Cancer Res 2004;64:4749-4754.
    • (2004) Cancer Res , vol.64 , pp. 4749-4754
    • Yap, D.B.1    Hsieh, J.K.2    Zhong, S.3
  • 10
    • 10744229026 scopus 로고    scopus 로고
    • Merlin neutralizes the inhibitory effect of Mdm2 on p53
    • Kim H, Kwak NJ, Lee JY, et al. Merlin neutralizes the inhibitory effect of Mdm2 on p53. J Biol Chem 2004;279:7812-7818.
    • (2004) J Biol Chem , vol.279 , pp. 7812-7818
    • Kim, H.1    Kwak, N.J.2    Lee, J.Y.3
  • 11
    • 0025237717 scopus 로고
    • Increased expression of the retinoblastoma gene in human colorectal carcinomas relative to normal colonic mucosa
    • Gope R, Christensen MA, Thorson A, et al. Increased expression of the retinoblastoma gene in human colorectal carcinomas relative to normal colonic mucosa. J Natl Cancer Inst 1990;82:310-314.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 310-314
    • Gope, R.1    Christensen, M.A.2    Thorson, A.3
  • 12
    • 0025913475 scopus 로고
    • Comparative study of the expression of Rb and p53 genes in human colorectal cancers, colon carcinoma cell lines and synchronized human fibroblasts
    • Gope ML, Chun M, Gope R. Comparative study of the expression of Rb and p53 genes in human colorectal cancers, colon carcinoma cell lines and synchronized human fibroblasts. Mol Cell Biochem 1991;107:55-63.
    • (1991) Mol Cell Biochem , vol.107 , pp. 55-63
    • Gope, M.L.1    Chun, M.2    Gope, R.3
  • 13
    • 20244368347 scopus 로고    scopus 로고
    • Altered structure and expression of RB1 gene and increased phosphorylation of pRb in human vestibular schwannomas
    • Thomas R, Antony Herald Prabhu PD, Mathivanan J, et al. Altered structure and expression of RB1 gene and increased phosphorylation of pRb in human vestibular schwannomas. Mol Cell Biochem 2005;271:113-121.
    • (2005) Mol Cell Biochem , vol.271 , pp. 113-121
    • Thomas, R.1    Antony Herald Prabhu, P.D.2    Mathivanan, J.3
  • 14
    • 0022569594 scopus 로고
    • Characterization of the human p53 gene
    • Lamb P, Crawford L. Characterization of the human p53 gene. Mol Cell Biol 1986;6:1379-1385.
    • (1986) Mol Cell Biol , vol.6 , pp. 1379-1385
    • Lamb, P.1    Crawford, L.2
  • 15
    • 0027512685 scopus 로고
    • Human breast cancer: Frequent p53 allele loss and protein overexpression
    • Singh S, Simon M, Meybohm I, et al. Human breast cancer: Frequent p53 allele loss and protein overexpression. Hum Genet 1993;90:635-640.
    • (1993) Hum Genet , vol.90 , pp. 635-640
    • Singh, S.1    Simon, M.2    Meybohm, I.3
  • 16
    • 0026697034 scopus 로고
    • Abundance and state of phosphorylation of the retinoblastoma susceptibility gene product in human colon cancer
    • Gope R, Gope ML. Abundance and state of phosphorylation of the retinoblastoma susceptibility gene product in human colon cancer. Mol Cell Biochem 1992;110:123-133.
    • (1992) Mol Cell Biochem , vol.110 , pp. 123-133
    • Gope, R.1    Gope, M.L.2
  • 17
    • 0038771963 scopus 로고    scopus 로고
    • The DDB2 nucleotide excision repair gene product p48 enhances global genomic repair in p53 deficient human fibroblasts
    • Fitch ME, Cross IV, Turner SJ, et al. The DDB2 nucleotide excision repair gene product p48 enhances global genomic repair in p53 deficient human fibroblasts. DNA Repair (Amst) 2003;2:819-826.
    • (2003) DNA Repair (Amst) , vol.2 , pp. 819-826
    • Fitch, M.E.1    Cross, I.V.2    Turner, S.J.3
  • 18
    • 22344432068 scopus 로고    scopus 로고
    • Altered gene expression in phenotypically normal renal cells from carriers of tumor suppressor gene mutations
    • Stoyanova R, Clapper ML, Bellacosa A, et al. Altered gene expression in phenotypically normal renal cells from carriers of tumor suppressor gene mutations. Cancer Biol Ther 2004;3:1313-1321.
    • (2004) Cancer Biol Ther , vol.3 , pp. 1313-1321
    • Stoyanova, R.1    Clapper, M.L.2    Bellacosa, A.3
  • 19
    • 0036064596 scopus 로고    scopus 로고
    • Genetic alterations in normal epithelium of colorectal cancer patients may be a useful indicator for subsequent metachronous tumor development
    • Koshiji M, Yonekura Y, Saito T, Sakaida N, Uemura Y, Yoshioka K. Genetic alterations in normal epithelium of colorectal cancer patients may be a useful indicator for subsequent metachronous tumor development. Ann Surg Oncol 2002;9:580-586.
    • (2002) Ann Surg Oncol , vol.9 , pp. 580-586
    • Koshiji, M.1    Yonekura, Y.2    Saito, T.3    Sakaida, N.4    Uemura, Y.5    Yoshioka, K.6
  • 20
    • 3843084923 scopus 로고    scopus 로고
    • Metastatic cancer DNA phenotype identified in normal tissues surrounding metastasizing prostate carcinomas
    • Malins DC, Gilman NK, Green VM, et al. Metastatic cancer DNA phenotype identified in normal tissues surrounding metastasizing prostate carcinomas. Proc Natl Acad Sci USA 2004;101:11428-11431.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11428-11431
    • Malins, D.C.1    Gilman, N.K.2    Green, V.M.3
  • 22
    • 0028353062 scopus 로고
    • Analysis of loss of heterozygosity (LOH) at the p53 and Rb suppressor genes in urinary bladder carcinoma
    • Tamada H, Suzuki Y, Tamura G. Analysis of loss of heterozygosity (LOH) at the p53 and Rb suppressor genes in urinary bladder carcinoma. Nippon Hinyokika Gakkai Zasshi 1994;85:722-730.
    • (1994) Nippon Hinyokika Gakkai Zasshi , vol.85 , pp. 722-730
    • Tamada, H.1    Suzuki, Y.2    Tamura, G.3
  • 23
    • 0031054104 scopus 로고    scopus 로고
    • Polymerase chain reaction-based approaches for detection of allelic loss in the p53 tumor suppressor gene in colon neoplasms
    • Yamaguchi K, Sugano K, Fukayama N, et al. Polymerase chain reaction-based approaches for detection of allelic loss in the p53 tumor suppressor gene in colon neoplasms. Am J Gastroenterol 1997;92:307-312.
    • (1997) Am J Gastroenterol , vol.92 , pp. 307-312
    • Yamaguchi, K.1    Sugano, K.2    Fukayama, N.3
  • 24
    • 0040431516 scopus 로고    scopus 로고
    • p53 mutation, EGFR gene amplification and loss of heterozygosity on chromosome 10, 17 p in human gliomas
    • Jin W, Xu X, Yang T, Hua Z. p53 mutation, EGFR gene amplification and loss of heterozygosity on chromosome 10, 17 p in human gliomas. Chin Med J (Engl) 2000;113:662-666.
    • (2000) Chin Med J (Engl) , vol.113 , pp. 662-666
    • Jin, W.1    Xu, X.2    Yang, T.3    Hua, Z.4
  • 25
    • 0028277935 scopus 로고
    • Post-thymic T cell lymphomas frequently overexpress p53 protein but infrequently exhibit p53 gene mutations
    • Matsushima AY, Cesarman E, Chadburn A, Knowles DM. Post-thymic T cell lymphomas frequently overexpress p53 protein but infrequently exhibit p53 gene mutations. Am J Pathol 1994;144:573-584.
    • (1994) Am J Pathol , vol.144 , pp. 573-584
    • Matsushima, A.Y.1    Cesarman, E.2    Chadburn, A.3    Knowles, D.M.4
  • 26
    • 1842432577 scopus 로고    scopus 로고
    • Loss of heterozygosity analysis of chromosome 17p13.1-13.3 and its correlation with clinical outcome in medulloblastomas
    • Jung HL, Wang KC, Kim SK, et al. Loss of heterozygosity analysis of chromosome 17p13.1-13.3 and its correlation with clinical outcome in medulloblastomas. J Neurooncol 2004;67:41-46.
    • (2004) J Neurooncol , vol.67 , pp. 41-46
    • Jung, H.L.1    Wang, K.C.2    Kim, S.K.3
  • 27
    • 0029985494 scopus 로고    scopus 로고
    • Loss of heterozygosity at the p53, RB, DCC and APC tumor suppressor gene loci in human bladder cancer
    • Miyamoto H, Shuin T, Ikeda I, Hosaka M, Kubota Y. Loss of heterozygosity at the p53, RB, DCC and APC tumor suppressor gene loci in human bladder cancer. J Urol 1996;155:1444-1447.
    • (1996) J Urol , vol.155 , pp. 1444-1447
    • Miyamoto, H.1    Shuin, T.2    Ikeda, I.3    Hosaka, M.4    Kubota, Y.5
  • 28
    • 0026547577 scopus 로고
    • p53 mutation and loss of heterozygosity on chromosomes 17 and 10 during human astrocytoma progression
    • Fults D, Brockmeyer D, Tullous MW, Pedone CA, Cawthon RM. p53 mutation and loss of heterozygosity on chromosomes 17 and 10 during human astrocytoma progression. Cancer Res 1992;52:674-679.
    • (1992) Cancer Res , vol.52 , pp. 674-679
    • Fults, D.1    Brockmeyer, D.2    Tullous, M.W.3    Pedone, C.A.4    Cawthon, R.M.5
  • 29
    • 13244299116 scopus 로고    scopus 로고
    • p53 polymorphisms associated with mutations in and loss of heterozygosity of the p53 gene in male oral squamous cell carcinomas in Taiwan
    • Hsieh LL, Huang TH, Chen IH, et al. p53 polymorphisms associated with mutations in and loss of heterozygosity of the p53 gene in male oral squamous cell carcinomas in Taiwan. Br J Cancer 2005:92:30-35.
    • (2005) Br J Cancer , vol.92 , pp. 30-35
    • Hsieh, L.L.1    Huang, T.H.2    Chen, I.H.3
  • 30
    • 0028198314 scopus 로고
    • Alterations of the TP53 gene in human gliomas
    • Rasheed BK, McLendon RE, Herndon JE, et al. Alterations of the TP53 gene in human gliomas. Cancer Res 1994;54:1324-1330.
    • (1994) Cancer Res , vol.54 , pp. 1324-1330
    • Rasheed, B.K.1    McLendon, R.E.2    Herndon, J.E.3
  • 31
    • 31044445232 scopus 로고    scopus 로고
    • Allelic losses at the p53 gene in primary human endometrial carcinomas
    • Semczuk A, Marzec B, Postawski K, et al. Allelic losses at the p53 gene in primary human endometrial carcinomas. Eur J Biochem 2003;1:P1.1-P35.
    • (2003) Eur J Biochem , vol.1
    • Semczuk, A.1    Marzec, B.2    Postawski, K.3
  • 33
    • 0028877255 scopus 로고
    • Detection of loss of heterozygosity of p53 gene in paraffin-embedded breast cancers by non-isotopic PCR-SSCP
    • Chen YH, Li CD, Yap EP, McGee JO. Detection of loss of heterozygosity of p53 gene in paraffin-embedded breast cancers by non-isotopic PCR-SSCP. J Pathol 1995;177:129-134.
    • (1995) J Pathol , vol.177 , pp. 129-134
    • Chen, Y.H.1    Li, C.D.2    Yap, E.P.3    McGee, J.O.4
  • 34
    • 0028978774 scopus 로고
    • p53 gene mutations, p53 protein accumulation and compartmentalization in colorectal adenocarcinoma
    • Bosari S, Viale G, Roncalli M, et al. p53 gene mutations, p53 protein accumulation and compartmentalization in colorectal adenocarcinoma. Am J Pathol 1995;147:790-798.
    • (1995) Am J Pathol , vol.147 , pp. 790-798
    • Bosari, S.1    Viale, G.2    Roncalli, M.3
  • 35
    • 8544230668 scopus 로고    scopus 로고
    • Comparison of the effect of mutant and wild-type p53 on global gene expression
    • O'Farrell TJ, Ghosh P, Dobashi N, Sasaki CY, Longo DL. Comparison of the effect of mutant and wild-type p53 on global gene expression. Cancer Res 2004;64:8199-8207.
    • (2004) Cancer Res , vol.64 , pp. 8199-8207
    • O'Farrell, T.J.1    Ghosh, P.2    Dobashi, N.3    Sasaki, C.Y.4    Longo, D.L.5
  • 36
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997;88:323-331.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 37
    • 0024512513 scopus 로고
    • Overexpression of normal human p53 in established fibroblasts leads to their tumorigenic conversion
    • Tuck SP, Crawford L Overexpression of normal human p53 in established fibroblasts leads to their tumorigenic conversion. Oncogene Res 1989;4:81-96.
    • (1989) Oncogene Res , vol.4 , pp. 81-96
    • Tuck, S.P.1    Crawford, L.2
  • 38
    • 0027764526 scopus 로고
    • High levels of p53 protein expression do not correlate with p53 gene mutations in anaplastic large cell lymphoma
    • Cesarman E, Inghirami G, Chadburn A, Knowles DM. High levels of p53 protein expression do not correlate with p53 gene mutations in anaplastic large cell lymphoma. Am J Pathol 1993;143:845-856.
    • (1993) Am J Pathol , vol.143 , pp. 845-856
    • Cesarman, E.1    Inghirami, G.2    Chadburn, A.3    Knowles, D.M.4
  • 39
    • 0027246716 scopus 로고
    • Regulation of p53 protein expression in human breast cancer cell lines
    • Vojtesek B, Lane DP. Regulation of p53 protein expression in human breast cancer cell lines. J Cell Sci 1993;105:607-612.
    • (1993) J Cell Sci , vol.105 , pp. 607-612
    • Vojtesek, B.1    Lane, D.P.2
  • 40
    • 16644396297 scopus 로고    scopus 로고
    • Wild-type p53 overexpression and its correlation with MDM2 and p14ARF alterations: An alternative pathway to non-small-cell lung cancer
    • Wang YC, Lin RK, Tan YH, Chen JT, Chen CY, Wang YC. Wild-type p53 overexpression and its correlation with MDM2 and p14ARF alterations: An alternative pathway to non-small-cell lung cancer. J Clin Oncol 2005;23:154-164.
    • (2005) J Clin Oncol , vol.23 , pp. 154-164
    • Wang, Y.C.1    Lin, R.K.2    Tan, Y.H.3    Chen, J.T.4    Chen, C.Y.5    Wang, Y.C.6
  • 42
    • 0027407260 scopus 로고
    • Wild-type p53 adopts a 'mutant'-like conformation when bound to DNA
    • Halazonetis TD, Davis LJ, Kandil AN. Wild-type p53 adopts a 'mutant'-like conformation when bound to DNA. EMBO J 1993;12:1021-1028.
    • (1993) EMBO J , vol.12 , pp. 1021-1028
    • Halazonetis, T.D.1    Davis, L.J.2    Kandil, A.N.3
  • 43
    • 17144418954 scopus 로고    scopus 로고
    • Apoptosis-stimulating protein p53-2 (ASPP2/53BP2L) is an E2F target gene
    • Chen D, Padiernos E, Ding F, Lossos IS, Lopez CD. Apoptosis-stimulating protein p53-2 (ASPP2/53BP2L) is an E2F target gene. Cell Death Differ 2005;12:358-368.
    • (2005) Cell Death Differ , vol.12 , pp. 358-368
    • Chen, D.1    Padiernos, E.2    Ding, F.3    Lossos, I.S.4    Lopez, C.D.5
  • 44
    • 15744406023 scopus 로고    scopus 로고
    • Abnormal stability of wild-type p53 protein in a human lung carcinoma cell line
    • Yamauchi M, Suzuki K, Kodama S, Watanabe M. Abnormal stability of wild-type p53 protein in a human lung carcinoma cell line. Biochem Biophys Res Commun 2005;330:483-488.
    • (2005) Biochem Biophys Res Commun , vol.330 , pp. 483-488
    • Yamauchi, M.1    Suzuki, K.2    Kodama, S.3    Watanabe, M.4
  • 46
    • 0036119999 scopus 로고    scopus 로고
    • Predictors of vestibular schwannoma growth in patients with neurofibromatosis Type 2
    • Baser ME, Makariou EV, Parry DM. Predictors of vestibular schwannoma growth in patients with neurofibromatosis Type 2. J Neurosurg 2002;96:217-222.
    • (2002) J Neurosurg , vol.96 , pp. 217-222
    • Baser, M.E.1    Makariou, E.V.2    Parry, D.M.3


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