Reduced bone mineral density in adults treated with high-dose corticosteroids for childhood nephrotic syndrome

Kidney International

Volumn 68, Issue 5, 2005, Pages 2304-2309

  Hegarty, Janet ^b   Mughal, M Zulf ^b   Adams, Judith ^b   Webb, Nicholas J A ^a  

^a ROYAL MANCHESTER CHILDREN S HOSPITAL   (United Kingdom)

^b NONE

Author keywords

Bone mineral density; Childhood minimal change nephrotic syndrome; Corticosteroids; Fracture risk; Trabecular bone density

Indexed keywords

CORTICOSTEROID;

ADULT; BONE ATROPHY; BONE DENSITOMETRY; BONE DENSITY; CLINICAL ARTICLE; COHORT ANALYSIS; CONFERENCE PAPER; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FEMUR NECK; FOLLOW UP; FRACTURE; HUMAN; LUMBAR SPINE; MALE; NEPHROTIC SYNDROME; PRIORITY JOURNAL; RADIUS; RISK ASSESSMENT; SPINE;

ADRENAL CORTEX HORMONES; ADULT; AGE FACTORS; BONE DENSITY; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; FEMALE; FRACTURES, BONE; HUMANS; MALE; NEPHROSIS, LIPOID; NEPHROTIC SYNDROME; RISK FACTORS;

EID: 30944465430     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1111/j.1523-1755.2005.00690.x     Document Type: Conference Paper

References (28)

1. HODSON EM, KNIGHT JF, WILLIS NS, CRAIG JC: Corticosteroid therapy in nephrotic syndrome: A meta-analysis of randomised controlled trials. Arch Dis Child 83:45-51, 2000
2. ANONYMOUS: The primary nephrotic syndrome in children: Identification of patients with minimal change nephrotic syndrome from initial response to prednisone. A report of the International Study of Kidney Disease in Children. J Pediatr 98:561-564, 1981
3. HOOYMAN JR, MELTON LJ, NELSON AM, et al: Fractures after rheumatoid arthritis - A population based study. Arthritis Rheum 27:1353-1361, 1984
4. LANE NE: An update on glucocorticoid-induced osteoporosis. Rheum Dis Clin North Am 27:235-243, 2001
5. WEINSTEIN RS, NICHOLAS RW, MANOLAGAS SC: Apoptosis of osteocytes in glucocorticoid-induced osteonecrosis of the hip. J Clin Endocrinol Metab 85:2907-2912, 2000
6. WEINSTEIN RS, CHEN JR, POWERS CC, et al: Promotion of osteoclast survival and antagonism of bisphosphonate-induced osteoclast apoptosis by glucocorticoids. J Clin Invest 109:1041-1048, 2002
7. REID IR, IBBERTSON HK: Evidence of decreased tubular reabsorption of calcium in glucocorticoid-treated asthmatics. Hormone Metab Res 27:200-204, 1987
8. MORRIS HA, NEED AG, O'LOUGHLIN PD, et al: Malabsorption of calcium in corticosteroid-induced osteoporosis. Calcif Tissue Int 46:305-308, 1990
9. COSMAN F, NIEVES J, HERBERT J, et al: High-dose glucocorticoids in multiple sclerosis patients exert direct effects on the kidney and skeleton. J Bone Miner Res 9:1097-1105, 1994
10. LEONARD MB, FELDMAN HI, SHULTS J, et al: Long-term, high-dose glucocorticoids and bone mineral content in childhood glucocorticoid-sensitive nephrotic syndrome. N Engl J Med 351:868-875, 2005
11. ESBJORNER E, ARVIDSSON B, JONES IL, PALMER M: Bone mineral content and collagen metabolites in children receiving steroid treatment for nephrotic syndrome. Acta Paediatr 90:1127-1130, 2001
12. SERACINI D, LAVORATTI GC, CIVININI A, et al: Bone mineral density in children with nephrotic syndrome. Pediatr Nephrol 10:C115, 1996
13. MORIN D, KOTSKI PO, DALLA VALE F, et al: Bone mineral density in children with steroid sensitive nephrotic syndrome. Pediatr Nephrol 10:C147, 1996
14. TENBROCK K, KRUPPA S, MOKOV E, et al: Analysis of muscle strength and bone structure in children with renal disease. Pediatr Nephrol 14:669-672, 2000
15. LETTGEN B, JEKEN C, REINERS C: Influence of steroid medication on bone mineral density in children with nephrotic syndrome. Pediatr Nephrol 8:667-670, 1994
16. GULATI S, GODBOLE M, SINGH U, et al: Are children with idiopathic nephrotic syndrome at risk for metabolic bone disease. Am J Kidney Dis 41:1163-1169, 2003
17. LEWIS MA, BAILDAM EM, DAVIS N, et al: Nephrotic syndrome: From toddlers to twenties. Lancet i:255-259, 1989
18. FREEMAN JV, COLE TJ, CHINN S, et al: Cross sectional stature and weight reference curves for the UK 1990. Arch Dis Child 73:17-24, 1995
19. COLE TJ, FREEMAN JV, PREECE MA: Body mass index reference curves for the UK 1990. Arch Dis Child 73:25-29, 1995
20. MATSUKURA H, INABA S, SHINOZAKI K, et al: Influence of prolonged corticosteroid therapy on the outcome of steroid-responsive nephrotic syndrome. Am J Nephrol 21:362-367, 2001
21. FOOTE KD, BROCKLEBANK JT, MEADOW SR: Height attainment in children with steroid-responsive nephrotic syndrome. Lancet ii:917-919, 1985
22. VAN STAA TP, LEUFKENS HG, COOPER C: The epidemiology of corticosteroid-induced osteoporosis: A meta-analysis. Osteoporos Int 13:777-787, 2002
23. HEANEY RP, MATKOVIC V: Inadequate peak bone mass, in Osteoporosis: Etiology, Diagnosis, and Management, 2nd ed., edited by, Riggs BL, Melton LJ III LJ, Philadelphia, Lippincott-Raven, 1995, pp 115-131
24. KELLY PJ. EISMAN JA. SAMBROOK PN: Interaction of genetic and environmental influences on peak bone density. Osteoporosos Int 1:56-60, 1990
25. MUGHAL MZ, WARD K, ADAMS J: Assessment of bone status in children by densitometric and quantitative ultrasound techniques, in Imaging Children, 2nd ed., edited by Carty H, Brunelle F, Stringer DA, et al, Edinburgh, Churchill Livingstone, 2005
26. RECKER RR: Bone remodeling abnormalities in osteoporosis, in Osteoporosis, edited by Marcus R, Feldman D, Kelsey J, New York, Academic Press, Inc., 1996, pp 703-713
27. COOPER MS, BUJALSKA I, RABBITT E, et al: Modulation of 11beta-hydroxysteroid dehydrogenase isozymes by proinflammatory cytokines in osteoblasts: An autocrine switch from glucocorticoid inactivation to activation. J Bone Miner Res 16:1037-1044, 2001
28. AUGAT P, REEB H, CLAES LE: Prediction of fracture load at different skeletal sites by geometric properties of the cortical shell. J Bone Miner Res 11:1356-1363, 1996