Phenotypic and genetic characterization of the Atp7aMo-Tohm mottled mouse: A new murine model of Menkes disease

Genomics

Volumn 87, Issue 2, 2006, Pages 191-199

  Mototani, Yasumasa ^a   Miyoshi, Ichiro ^b   Okamura, Tadashi ^a   Moriya, Takuya ^c   Meng, Yan ^a   Yuan Pei, Xiang ^a   Kameo, Satomi ^a   Kasai, Noriyuki ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^c TOHOKU UNIVERSITY HOSPITAL   (Japan)

Author keywords

Atp7a; Copper deficiency; Embryonic lethality; Menkes disease; Mottled mouse; Transgene; Yolk sac

Indexed keywords

COPPER; DNA; MENKES PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLEEDING; BLOOD VESSEL; BRAIN; BRAIN CELL; COPPER DEFICIENCY; DEATH; DNA SEQUENCE; EMBRYO; ENDOTHELIUM CELL; FEMALE; GENE AMPLIFICATION; GENE DELETION; GENE FUNCTION; GENE MUTATION; GENETIC DISORDER; GENETIC TRAIT; HETEROZYGOSITY; HOMEOSTASIS; IMMUNOHISTOCHEMISTRY; INTESTINE; LETHALITY; MALE; MENKES SYNDROME; MESODERM; MORPHOLOGICAL TRAIT; MOUSE; MUTATIONAL ANALYSIS; NERVE DEGENERATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PIGMENTATION; PRIORITY JOURNAL; SURVIVAL RATE; TRANSGENE; YOLK SAC;

ADENOSINE TRIPHOSPHATASES; ANIMALS; BASE SEQUENCE; CATION TRANSPORT PROTEINS; DISEASE MODELS, ANIMAL; DNA PRIMERS; FEMALE; GENES, LETHAL; IN SITU NICK-END LABELING; MALE; MENKES KINKY HAIR SYNDROME; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; PHENOTYPE; TRANSGENES;

ANIMALIA; MURINAE;

EID: 30944461332     PISSN: 08887543     EISSN: 10898646     Source Type: Journal    
DOI: 10.1016/j.ygeno.2005.09.011     Document Type: Article

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