Recent issues on the initial phase of warfarin treatment;Attuali problemi nella fase iniziale dei trattamenti con warfarin

Recenti Progressi in Medicina

Volumn 96, Issue 12, 2005, Pages 612-615

  Squizzato, Alessandro ^a   Steidl, Luigi ^a   Ageno, Walter ^a,b  

^a UNIVERSITY OF INSUBRIA   (Italy)

^b OSPEDALE DI CIRCOLO   (Italy)

Author keywords

Initiation dosing; Oral anticoagulants; Vitamin K antagonist; Warfarin

Indexed keywords

ANTICOAGULANT AGENT; ANTIVITAMIN K; WARFARIN;

ALGORITHM; ANTICOAGULATION; BLEEDING; CARDIOPULMONARY BYPASS; CLINICAL TRIAL; DISEASE PREDISPOSITION; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG METABOLISM; EVIDENCE BASED MEDICINE; HOSPITALIZATION; HUMAN; INDIVIDUALIZATION; INTERNATIONAL NORMALIZED RATIO; OUTPATIENT; PHARMACODYNAMICS; REVIEW; THROMBOEMBOLISM; VENOUS THROMBOEMBOLISM;

AGE FACTORS; ALGORITHMS; ANTICOAGULANTS; CLINICAL TRIALS; CORONARY ARTERY BYPASS; DRUG ADMINISTRATION SCHEDULE; EVIDENCE-BASED MEDICINE; HEMORRHAGE; HUMANS; INPATIENTS; INTERNATIONAL NORMALIZED RATIO; OUTPATIENTS; THROMBOEMBOLISM; VITAMIN K; WARFARIN;

EID: 30944458205     PISSN: 00341193     EISSN: 00341193     Source Type: Journal    
DOI: None     Document Type: Review

References (16)

1. Ansell J, Hirsh J, Poller L, Bussey H, Jacobson A, Hylek E. The pharmacology and management of the vitamin K antagonists. Chest 2004; 126: 204S-233S.
2. Palareti G, Leali N, Coccheri S, et al. Bleeding complications of oral anticoagulant treatment: an inception-cohort, prospective collaborative study (ISCOAT). Lancet 1996; 348: 423-8.
3. Ageno W, Turpie AGG. A randomized comparison of a computer-based dosing program with a manual system to monitor oral anticoagulant therapy. Thromb Res 1998; 91: 237-40.
4. Fennerty A, Dolmen J, Thomas P, et al. Flexible induction dose regimen for warfarin and prediction of maintenance dose. BMJ 1984; 288: 1268-70.
5. Carter BL, Taylor JW, Becker A. Evaluation of three dosage prediction methods for initial in-hospital stabilization of warfarin therapy. Clin Pharm 1987; 6: 37-45.
6. White RH, Hong R, Venook AP, et al. Initiation of warfarin therapy: comparison of physician dosing with computer-assisted dosing. J Gen Intern Med 1987; 2: 141-8.
7. Jupe DML, Peterson GM, Coleman RL, McLean S. Warfarin dosage requirements: prospective clinical trials of a method for prediction from the response to a single dose. Br J Clin Pharmacol 1988; 25: 607-10.
8. Ageno W, Turpie AGG. A computer generated induction system for hospitalized patients starting on oral anticoagulant therapy. Thromb Haemost 2000; 83: 849-52.
9. Harrison L, Johnston M, Massicotte MP, Crowther M, Moffat K, Hirsh J. Comparison of 5-mg and 10-mg loading doses in initiation of warfarin therapy. Ann Intern Med 1997; 126: 133-6.
10. Crowther MA, Ginsberg JB, Kearon C, Harrison L, Johnson J, Massicotte MP, Hirsh J. A randomized trial comparing 5 mg and 10 mg warfarin loading doses. Arch Intern Med 1999; 159: 46-8.
11. Kovacs MJ, Rodger M, Anderson DR, Morrow B, Kells G, Kovacs J, et al. Comparison of 10 mg and 5 mg warfarin initiation nomograms together with low molecular weight heparin for outpatient treatment of acute venous thromboembolism. Ann Intern Med 2003; 138: 714-9.
12. Ageno W, Turpie AG, Steidl L, Ambrosini F, Cattaneo R, Codari RL, Nardo B, Venco A. Comparison of a daily fixed 2.5 mg warfarin dose with a 5 mg, international normalized ratio adjusted, warfarin dose initially following heart valve replacement. Am J Cardiol 2001; 88: 40-4.
13. Ageno W, Johnson J, Nowacki B, Sloane D, Turpie AGG. The role of coagulation factors II, V, VII, and X in the response to oral anticoagulants in patients following heart valve replacement. Thromb Res 1998; 91: S81.
14. Ageno W, Steidl L, Ultori C, Dentali F, Marchesi C, Mera V, et al. The initial phase of oral anticoagulation with warfarin in outpatients with deep venous thrombosis. Blood Coagul Fibrinolysis 2003; 14: 11-4.
15. Gedge J, Orme S, Hampton KK, Channer KS, Hendra TJ. A comparison of a low dose warfarin induction regimen with the modified Fennerty regimen in elderly inpatients. Age Aging 2000; 29: 31-4.
16. Siguret V, Gouin I, Debray M, Perret-Guillaume C, Boddaert J, Mahe I, et al. Initiation of warfarin therapy in elderly medical inpatients: a safe and accurate regimen. Am J Med 2004; 118: 137-42.