Neurosyphilis with optic neuritis: An update

Postgraduate Medical Journal

Volumn 82, Issue 963, 2006, Pages 36-39

  Smith, G T ^a   Goldmeier, D ^b   Migdal, C ^a  

^a WESTERN EYE HOSPITAL   (United Kingdom)

^b ST MARY S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BENZATHINE PENICILLIN; DOXYCYCLINE; PENICILLIN G; PREDNISOLONE;

ADULT; CASE REPORT; CEREBROSPINAL FLUID ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE ANGIOGRAPHY; FOLLOW UP; HOMOSEXUALITY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MALE; NEUROSYPHILIS; OPHTHALMOSCOPY; OPTIC NEURITIS; RASH; REAGIN TEST; REVIEW; SLIT LAMP; TREPONEMA PALLIDUM; URETHRITIS; VISUAL ACUITY; VISUAL IMPAIRMENT;

ADULT; ANTI-BACTERIAL AGENTS; BLINDNESS; EYE INFECTIONS, BACTERIAL; HOMOSEXUALITY, MALE; HUMANS; MALE; MICROBIOLOGICAL TECHNIQUES; NEUROSYPHILIS; OPTIC NEURITIS;

EID: 30944454277     PISSN: 00325473     EISSN: None     Source Type: Journal    
DOI: 10.1136/pgmj.2004.020875     Document Type: Review

References (16)

1. Tichonova L, Borisenko K, Ward H, et al. Epidemics of syphilis in the Russian Federation: trends, origins, and priorities for control. Lancet 1997;350:210-13.
2. Tamesis RR, Foster CS. Ocular syphilis. Ophthalmology 1990;97:1281-7.
3. Lukehart SA, Hook EW, Baker-Zander SA, et al. Invasion of the central nervous system by Treponema pallidum: implications for diagnosis and treatment. Ann Intern Med 1988;109:855-62.
4. Margo CE, Hamed LM. Ocular syphilis. Surv Ophthalmol 1992;37:203-20.
5. Walsh FB, Hoyt WF. Infections and parasitic invasions of the nervous system. In: Clinical neuro-ophthalmology. 3rd ed. Vol 2. Baltimore: Williams and Wilkins, 1969:1581-91.
6. Gourevitch MN, Serwyn PA, Davenny K, et al. Effects of HIV infection on the serologic manifestations and responses to treatment of syphilis in intravenous drug users. Ann Intern Med 1993;118:350-5.
7. Goh BT, van Voost Vader PC. European guidelines for the management of syphilis. Int J STD AIDS. 2001;12:14-26, (http://www.iusti.org/guidelines.pdf), (suppl 3).
8. Centers for Disease Control and Prevention. Sexually transmitted disease guidelines 2002. MMWR. 2002;51:18-30, (http://www.cdc.gov/STD/treatment/rr5106. pdf).
9. Mohr JA, Griffiths W, Jackson R, et al. Neurosyphilis and penicillin levels in the cerebrospinal fluid. JAMA 1976;236:2208-9.
10. Johns DR, Tierney M, Felsenstein D. Alteration in the natural history of neurosyphilis by concurrent infection with human immunodeficiency virus. N Engl J Med 1987;316:1569-72.
11. Barza M, Baum J. Penetration of ocular compartments by penicillins. Surv Ophthalmol 1973;18:71-82.
12. Greene BM, Miller NR, Bynum TE. Failure of penicillin G benzathine in the treatment of neurosyphilis. Arch Intern Med 1980;140:1117-18.
13. Abramson IJ, Smibert RM. Inhibition of growth of treponemes by antimicrobial agents. Br J Vener Dis 1971;47:407-12.
14. Yim CW, Flynn NM, Fitzgerald FT. Penetration of oral doxycycline into the cerebrospinal fluid of patients with latent or neurosyphilis. Antimicrobial Agents Chemother 1985;28:347-8.
15. Poirer RH, Ellison AC. Ocular penetration of orally administered minocyclin. Ann Ophthalmol 1951;46:1859-61.
16. Odenholt I, Löwdin E, Cars O. Studies of the killing kinetics of benzylpenicillin, cefuroxime, azithromycin, and sparofloxacin on bacteria in the postantibiotic phase. Antimicrobial Agents Chemother 1997;41:2522-6.