Inadequate use of acid-suppressive therapy in hospitalized patients and its implications for general practice

Digestive Diseases and Sciences

Volumn 50, Issue 12, 2005, Pages 2307-2311

  Scagliarini, Raffaella ^a   Magnani, Elena ^a   Praticò, Antonino ^a   Bocchini, Renato ^a   Sambo, Paola ^a   Pazzi, Paolo ^a,b  

^a BUFALINI HOSPITAL   (Italy)

^b M Bufalini Hospital   (Italy)

Author keywords

Acid suppressive therapy; Appropriateness; Prescribing habits; Proton pump inhibitors

Indexed keywords

HISTAMINE H2 RECEPTOR ANTAGONIST; PROTON PUMP INHIBITOR;

AGED; ARTICLE; CONTROLLED STUDY; DRUG MISUSE; DRUG USE; FEMALE; GENERAL PRACTICE; HIGH RISK PATIENT; HOSPITAL ADMISSION; HOSPITAL DEPARTMENT; HOSPITAL PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL ASSESSMENT; PRESCRIPTION; PRIORITY JOURNAL; RISK ASSESSMENT; RISK BENEFIT ANALYSIS; STOMACH ACID SECRETION; STOMACH PH; STOMACH ULCER; TREATMENT INDICATION;

AGE FACTORS; AGED; AGED, 80 AND OVER; ANTACIDS; ANTI-ULCER AGENTS; ATTITUDE OF HEALTH PERSONNEL; DRUG UTILIZATION; FAMILY PRACTICE; FEMALE; HEALTH CARE SURVEYS; HOSPITALS, COMMUNITY; HUMANS; ITALY; MALE; MIDDLE AGED; PHYSICIAN'S PRACTICE PATTERNS; PROTON PUMPS; RISK ASSESSMENT; SEX FACTORS;

EID: 30944444387     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-005-3052-4     Document Type: Article

References (33)

1. Nardino RJ, Vender RJ, Herbert PN: Overuse of acid-suppressive therapy in hospitalized patients. Am J Gastroenterol 95:3118-3122, 2000
2. Parente F, Cucino C, Gallus S, Bargiggia S, Greco S, Pastore L, Bianchi Porro G: Hospital use of acid-suppressive medications and its fall-out on prescribing in general practice: a 1-month survey. Aliment Pharmacol Ther 17:1503-1506, 2003
3. Jacobson BC, Ferris TG, Shea TL, Mahlis EM, Lee TH, Wang TC: Who is using chronic acid suppression therapy and why? Am J Gastroenterol 98:51-58, 2003
4. Boutet R, Wilcock M, MacKenzie I: Survey on repeat prescribing for acid suppression drugs in primary care in Cornwall and the Isles of Scilly. Aliment Pharmacol Ther 13:813-817, 1999
5. Goudie BM, McKenzie PE, Cipriano J, Griffin EM, Murray FE: Repeat prescribing of ulcer healing drugs in general practice. Prevalence and underlying diagnosis. Aliment Pharmacol Ther 10:147-150, 1996
6. Ryder SD, O'Reilly S, Miller RJ, Ross J, Jacyna MR, Levi AJ: Long term acid suppressing treatment in general practice. BMJ 308:827-830, 1994
7. Gullotta R, Ferraris L, Cortelezzi C, Minoli G, Prada A, Comin U, Rocca F, Ferrara A, Curzio M: Are we correctly using the inhibitors of gastric acid secretion and cytoprotective drugs? Results of a multicentre study. Ital J Gatroenterol Hepatol 29:325-329, 1997
8. Strid H, Simren M, Bjornsson ES: Overuse of acid suppressant drugs in patients with chronic renal failure. Nephrol Dial Transplant 18:570-575, 2003
9. Sebastian SS, Kernan N, Qasim A, O'Morain CA, Buckley M: Appropriateness of gastric anti-secretory therapy in hospital practice. Ir J Med Sci 172:115-117, 2003
10. Il primo rapporto nazionale sull'uso dei farmaci in Italia nel I semestre 2000. Boll Inform Farm 1/8:42-13, 2001
11. Valori RM, Brown CM, Strangeways P, Bradburn M: Reducing community dyspepsia drug costs: a controlled trial. Gut 49:495-501, 2001
12. Katz PO, Tutuian R: Histamin receptor antagonists, proton pump inhibitors and their combination in the treatment of gastro-esophageal reflux disease. Best Pract Res Clin Gastroenterol 15:371-384, 2001
13. Soo S, Moayyedi P, Deeks J, Delaney B, Innes M, Forman D: Pharmacological interventions for non-ulcer dyspepsia. Cochrane Database Syst Rev (2) CD001960, 2000
14. Howden WC, Leontiadis GI: Current indications for acid suppressants in Helicobacter pylori negative ulcer disease. Best Pract Res Clin Gastroenterol 15:401-412, 2001
15. Soll AH: Consensus Conference. Medical treatment of peptic ulcer disease. Practice guidelines. JAMA 275:622-629, 1996
16. Dubois RW, Melmed GY, Henning JM, Laine L: Guidelines for the appropriate use of non steroidal anti-inflammatory drugs, cyclo-oxygenase 2-specific inhibitors and proton pump inhibitors in patients requiring chronic anti-inflammatory therapy. Aliment Pharmacol Ther 19:197-208, 2004
17. Lau JY, Sung JJ, Lee KK, Yung MY, Wong SK, Wu JC, Chan FK, Ng EK, You JH, Lee CW, Chan AC, Chung SC: Effect of intravenous omeprazole on recurrent bleeding after endoscopy treatment of bleeding peptic ulcers. N Engl J Med 343:310-316, 2000
18. Naunton M, Peterson GM, Bleasel MD: Overuse of proton pump inhibitors. J Clin Pharm Ther 25:333-340, 2000
19. Niklasson A, Bajor A, Bergendal L, Simren M, Strid H, Bjornsson E: Overuse of acid suppressive therapy in hospitalized patients with pulmonary diseases. Respir Med 97:1143-1150, 2003
20. Sherman DS, Avorn J, Campion EW: Cimetidine use in nursing homes: prolonged therapy and excessive doses. J Am Geriatr Soc 35:1023-1027, 1987
21. Yeomans ND, Tulassay Z, Juhasz L, Racz I, Howard JM, van Rensburg CJ, Swannell AJ, Hawkey CJ: A comparison of omeprazole with ranitidine for ulcers associated with non-steroidal antiinflammatory drugs. Acid Suppression Trial: Ranitidine versus Omeprazole for NSAID-associated Ulcer Treatment (ASTRO-NAUT) Study Group. N Engl J Med 338:719-726, 1998
22. Silverstein FE, Graham DY, Senior JR, Davies HW, Struthers BJ, Bittman RM, Geis GS: Misoprostol reduces serious gastrointestinal complications in patients with rheumatoid arthritis receiving non-steroidal anti-inflammatory drugs. A randomized, double-blind placebo-controlled trial. Ann Intern Med 123:241-249, 1995
23. Rostom A, Dube C, Wells G, Tugwell P, Welch V, Jolicoeur E, McGowan J: Prevention of NSAID-induced gastroduodenal ulcers. Cochrane Database Syst Rev (4):CD002296, 2002
24. Taha AS, Hudson N, Hawkey CJ, Swannell AJ, Trye PN, Cottrel J, Mann SG, Simon TJ, Sturrock RD, Russell RI: Famotidine for the prevention of gastric and duodenal ulcers caused by non-steroidal antiinflammatory drugs. N Engl J Med 334:1435-1439, 1996
25. Hudson N, Taha AS, Russell RI, Trye PN, Cottrel J, Mann SG, Swannell AJ, Sturrock RD, Hawkey CJ: Famotidine for healing and maintenance in nonsteroidal anti-inflammatory drug-associated gastroduodenal ulcerations. Gastroenterology 11:1817-1822, 1997
26. Aalykke C, Lauritsen K: Epidemiology of NSAID-related gastroduodenal mucosal injury. Best Pract Res Clin Gastroenterol 15:705-722, 2001
27. Conn HO, Blitzer BL: Nonassociation of adrenocorticosteroid therapy and peptic ulcer. N Engl J Med294:473-479, 1976
28. Piper JM, Ray WA, Daugherty JR, Griffin MR: Corticosteroid use and peptic ulcer disease: role of nonsteroidal anti-inflammatory drugs. Ann Intern Med 114:735-740, 1991
29. Conn HO, Poynard T: Corticosteroids and peptic ulcer: meta-analysis of adverse events during steroid therapy. J Intern Med 236:619-632, 1994
30. Shorr RI, Ray WA, Daugherty JR, Griffin MR: Concurrent use of nonsteroidal anti-inflammatory drugs and oral anticoagulants places elderly persons at high risk for hemorrhagic peptic ulcer disease. Arch Intern Med 153:1665-1670, 1993
31. Gutthann SP, Garcia Rodriguez LA, Raiford DS: Individual nonsteroidal anti-inflammatory drugs and others risk factors for upper gastrointestinal bleeding and perforation. Epidemiology 8:18-24, 1997
32. Petty GW, Brown RD, Whisnant JP, Sicks JD, O'Fallon WM, Wiebers DO: Frequency of major complications of aspirin, warfarin and intravenous heparin for secondary stroke prevention: a population-based study. Ann Intern Med 130:14-22, 1999
33. Smalley W, Stein CM, Arbogast G, Eisen J, Ray WA, Griffin GM: Underutilisation of gastroprotective measures in patients receiving nonsteroidal antiinflammatory drugs. Arth Rheum 46:2195-2200, 2002