Report of an unusual problematic uterine smooth muscle neoplasm, emphasizing the prognostic importance of coagulative tumor cell necrosis

International Journal of Gynecological Cancer

Volumn 15, Issue 6, 2005, Pages 1210-1212

  Amant, Frederic ^a,b   Moerman, P ^b   Vergote, I ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

Leiomyoma; Leiomyosarcoma; Prognostic; Sarcoma; Uterus

Indexed keywords

MEDROXYPROGESTERONE ACETATE;

ADULT; ANAMNESIS; ARTICLE; CASE REPORT; CLINICAL FEATURE; DISEASE FREE SURVIVAL; FEMALE; FOLLOW UP; HUMAN; IMMUNOHISTOCHEMISTRY; LAPAROTOMY; LEIOMYOSARCOMA; MICROSCOPY; MITOSIS INDEX; MYOMETRIUM; PRIORITY JOURNAL; PROGNOSIS; RETROPERITONEAL TUMOR; TUMOR CELL; TUMOR NECROSIS; UTERUS CANCER;

FEMALE; HUMANS; LEIOMYOSARCOMA; MIDDLE AGED; MITOTIC INDEX; NECROSIS; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; RETROPERITONEAL NEOPLASMS; SMOOTH MUSCLE TUMOR; UTERINE NEOPLASMS;

EID: 30944442053     PISSN: 1048891X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1525-1438.2005.00183.x     Document Type: Article

References (15)

1. Zaloudek C, Hendrickson M. Mesenchymal tumors of the uterus. In: Kurmart R, ed. Blaustein's pathology of the female genital tract. New York: Springer-Verlag, 2002:561-615.
2. Bell S, Kempson R, Hendrickson M. Problematic uterine smooth muscle neoplasms. A clinicopathologic study of 213 cases. Am J Surg Pathol 1994;18:535-8.
3. Clement P. The pathology of uterine smooth muscle tumors and mixed endometrial stromal-smooth muscle tumors: a selective review with emphasis on recent advances, Int J Gynecol Pathol 2000;19:39-55.
4. Hart W. Problematic uterine smooth muscle neoplasms [letter]. Am J Surg Pathol 1997;21:252.
5. Omura G, Blessing J, Major F et al. A randomized clinical trial of adjuvant adriamycin in uterine sarcomas: a gynaecologic oncology group study. J Clin Oncol 1985;3:1240-5.
6. Reed N, Mangioni C, Malmstrom H et al. First results of a randomized trial comparing radiotherapy versus observation postoperatively in patients with uterine sarcomas. An EORTC-GCG study. Int J Gynecol Cancer 2003;13S:4.
7. Abeln E, Smit V, Wessels J et al. Molecular genetic evidence for the conversion hypothesis of the origin of malignant mixed mullerian tumours. J Pathol 1997;183:424-31.
8. Kounelis S, Jones M, Papadaki H et al. Carcinosarcomas (malignant mixed Mullerian tumors) of the female genital tract: comparative molecular analysis of epithelial and mesenchymal components. Hum Pathol 1998;29:82-7.
9. Silverberg S, Major F, Blessing J et al. Carcinosarcoma (malignant mixed mesodermal tumor) of the uterus. A Gynecological Oncology Group pathologic study of 203 cases, Int J Gynecol Pathol 1990;9:1-19.
10. Oliva E, Clement P, Young R. Endometrial stromal tumors: an update on a group of tumors with a protean phenotype. Adv Anat Pathol 2000;7:257-81.
11. Trzyna W, McHugh M, McCue P et al. Molecular determination of the malignant potential of smooth muscle neoplasms. Cancer 1997; 80:211-7.
12. Zhai Y-L, Kobayashi Y, Mori A et al. Expression of steroid receptors, Ki-67, and p53 in uterine leiomyosarcomas. Int J Gynecol Pathol 1999;18:20-8.
13. Bekker R, Massuger L, vd Berg P et al. Uterine malignant leiomyoblastoma (epithelioid leiomyosarcoma) during pregnancy. Gynecol Oncol 1999;72:433-6.
14. Tavassoli F, Norris H. Peritoneal leiomyomatosis (leiomyomatosis peritonealis disseminata): a clinicopathologic study of 20 cases with ultrastructural observations. Int J Gynecol Pathol 1982;1:59-74.
15. Dreyer L, Simson I Sevenster C, Dittrich O. Leiomyomatosis peritonealis disseminata. A report of two cases and a review of literature. Br J Obstet Gynaecol 1985;92:856-61.