메뉴 건너뛰기




Volumn 47, Issue 1, 2006, Pages 123-133

Identification of quantitative trait loci that regulate obesity and serum lipid levels in MRL/MpJ x SJL/J inbred mice

Author keywords

Body fat mass; Cholesterol; HDL cholesterol; Triglyceride

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

EID: 30844459017     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M500295-JLR200     Document Type: Article
Times cited : (15)

References (49)
  • 1
    • 0014976138 scopus 로고
    • Serum cholesterol, lipoproteins, and the risk of coronary heart disease: The Framingham Study
    • Kannel, W., W. Castelli, T. Gordon, and P. McNamara. 1971. Serum cholesterol, lipoproteins, and the risk of coronary heart disease: the Framingham Study. Ann. Intern. Med. 74: 1-12.
    • (1971) Ann. Intern. Med. , vol.74 , pp. 1-12
    • Kannel, W.1    Castelli, W.2    Gordon, T.3    McNamara, P.4
  • 3
    • 0039416145 scopus 로고    scopus 로고
    • Battling heart disease
    • Breslow, J. I. 1996. Battling heart disease. Science. 273: 15.
    • (1996) Science , vol.273 , pp. 15
    • Breslow, J.I.1
  • 5
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
    • Brown, M. S., and J. L. Goldstein. 1997. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell. 89: 331-340.
    • (1997) Cell , vol.89 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 6
    • 0028228359 scopus 로고
    • Linkage analysis of the genetic determinants of high density lipoprotein concentrations and composition: Evidence for involvement of the apolipoprotein A-II and cholesteryl ester transfer protein loci
    • Bu, X., C. H. Warden, Y. R. Xia, C. De Meester, D. L. Puppione, S. Teruya, B. Lokensgard, S. Daneshmand, J. Brown, R. J. Gray, et al. 1994. Linkage analysis of the genetic determinants of high density lipoprotein concentrations and composition: evidence for involvement of the apolipoprotein A-II and cholesteryl ester transfer protein loci. Hum. Genet. 93: 639-648.
    • (1994) Hum. Genet. , vol.93 , pp. 639-648
    • Bu, X.1    Warden, C.H.2    Xia, Y.R.3    De Meester, C.4    Puppione, D.L.5    Teruya, S.6    Lokensgard, B.7    Daneshmand, S.8    Brown, J.9    Gray, R.J.10
  • 10
    • 0038352163 scopus 로고    scopus 로고
    • Quantitative trait locus analysis of serum insulin, triglyceride, total cholesterol and phospholipid levels in the (SM/J x A/J)F2 mice
    • Anunciado, R. V., M. Nishimura, M. Mori, A. Ishikawa, S. Tanaka, F. Horio, T. Ohno, and T. Namikawa. 2003. Quantitative trait locus analysis of serum insulin, triglyceride, total cholesterol and phospholipid levels in the (SM/J x A/J)F2 mice. Exp. Anim. 52: 37-42.
    • (2003) Exp. Anim. , vol.52 , pp. 37-42
    • Anunciado, R.V.1    Nishimura, M.2    Mori, M.3    Ishikawa, A.4    Tanaka, S.5    Horio, F.6    Ohno, T.7    Namikawa, T.8
  • 11
    • 0034220290 scopus 로고    scopus 로고
    • Distribution of body weight, blood insulin and lipid levels in the SMXA recombinant inbred strains and the QTL analysis
    • Anunciado, R. V., T. Ohno, M. Mori, A. Ishikawa, S. Tanaka, F. Horio, M. Nishimura, and T. Namikawa. 2000. Distribution of body weight, blood insulin and lipid levels in the SMXA recombinant inbred strains and the QTL analysis. Exp. Anim. 49: 217-224.
    • (2000) Exp. Anim. , vol.49 , pp. 217-224
    • Anunciado, R.V.1    Ohno, T.2    Mori, M.3    Ishikawa, A.4    Tanaka, S.5    Horio, F.6    Nishimura, M.7    Namikawa, T.8
  • 12
    • 0031214118 scopus 로고    scopus 로고
    • Obesity QTLs on mouse chromosomes 2 and 17
    • Taylor, B. A., and S. J. Phillips. 1997. Obesity QTLs on mouse chromosomes 2 and 17. Genomics. 43: 249-257.
    • (1997) Genomics , vol.43 , pp. 249-257
    • Taylor, B.A.1    Phillips, S.J.2
  • 13
    • 0032534737 scopus 로고    scopus 로고
    • Genetic determinants of autoimmune disease and coronary vasculitis in the MRL-lpr/lpr mouse model of systemic lupus erythematosus
    • Gu, L., A. Weinreb, X. P. Wang, D. J. Zack, J. H. Qiao, R. Weisbart, and A. J. Lusis. 1998. Genetic determinants of autoimmune disease and coronary vasculitis in the MRL-lpr/lpr mouse model of systemic lupus erythematosus. J. Immunol. 161: 6999-7006.
    • (1998) J. Immunol. , vol.161 , pp. 6999-7006
    • Gu, L.1    Weinreb, A.2    Wang, X.P.3    Zack, D.J.4    Qiao, J.H.5    Weisbart, R.6    Lusis, A.J.7
  • 16
    • 2142751020 scopus 로고    scopus 로고
    • Influence of sex and diet on quantitative trait loci for HDL cholesterol levels in an SM/J by NZB/BlNJ intercross population
    • Korstanje, R., R. Li, T. Howard, P. Kelmenson, J. Marshall, B. Paigen, and G. Churchill. 2004. Influence of sex and diet on quantitative trait loci for HDL cholesterol levels in an SM/J by NZB/BlNJ intercross population. J. Lipid Res. 45: 881-888.
    • (2004) J. Lipid Res. , vol.45 , pp. 881-888
    • Korstanje, R.1    Li, R.2    Howard, T.3    Kelmenson, P.4    Marshall, J.5    Paigen, B.6    Churchill, G.7
  • 17
  • 18
    • 3843133845 scopus 로고    scopus 로고
    • Genetic contributors to lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and RIIIS/J inbred mice
    • Lyons, M. A., R. Korstanje, R. Li, K. A. Walsh, G. A. Churchill, M. C. Carey, and B. Paigen. 2004. Genetic contributors to lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and RIIIS/J inbred mice. Physiol. Genomics. 17: 114-121.
    • (2004) Physiol. Genomics , vol.17 , pp. 114-121
    • Lyons, M.A.1    Korstanje, R.2    Li, R.3    Walsh, K.A.4    Churchill, G.A.5    Carey, M.C.6    Paigen, B.7
  • 19
    • 0042995279 scopus 로고    scopus 로고
    • Quantitative trait loci that determine lipoprotein cholesterol levels in DBA/2J and CAST/Ei inbred mice
    • Lyons, M. A., H. Wittenburg, R. Li, K. A. Walsh, G. A. Churchill, M. C. Carey, and B. Paigen. 2003. Quantitative trait loci that determine lipoprotein cholesterol levels in DBA/2J and CAST/Ei inbred mice. J. Lipid Res. 44: 953-967.
    • (2003) J. Lipid Res. , vol.44 , pp. 953-967
    • Lyons, M.A.1    Wittenburg, H.2    Li, R.3    Walsh, K.A.4    Churchill, G.A.5    Carey, M.C.6    Paigen, B.7
  • 20
    • 1842509784 scopus 로고    scopus 로고
    • Quantitative trait loci that determine lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and CAST/Ei inbred mice
    • Lyons, M. A., H. Wittenburg, R. Li, K. A. Walsh, R. Korstanje, G. A. Churchill, M. C. Carey, and B. Paigen. 2004. Quantitative trait loci that determine lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and CAST/Ei inbred mice. Physiol. Genomics. 17: 60-68.
    • (2004) Physiol. Genomics , vol.17 , pp. 60-68
    • Lyons, M.A.1    Wittenburg, H.2    Li, R.3    Walsh, K.A.4    Korstanje, R.5    Churchill, G.A.6    Carey, M.C.7    Paigen, B.8
  • 21
    • 0032966978 scopus 로고    scopus 로고
    • Quantitative trait locus analysis of plasma lipoprotein levels in an autoimmune mouse model: Interactions between lipoprotein metabolism, autoimmune disease, and atherogenesis
    • Gu, L., M. W. Johnson, and A. J. Lusis. 1999. Quantitative trait locus analysis of plasma lipoprotein levels in an autoimmune mouse model: interactions between lipoprotein metabolism, autoimmune disease, and atherogenesis. Arterioscler. Thromb. Vasc. Biol. 19: 442-453.
    • (1999) Arterioscler. Thromb. Vasc. Biol. , vol.19 , pp. 442-453
    • Gu, L.1    Johnson, M.W.2    Lusis, A.J.3
  • 22
    • 2542465699 scopus 로고    scopus 로고
    • A novel mouse chromosomeomosome 2 congenic strain with obesity phenotypes
    • Diament, A. L., P. Farahani, S. Chiu, J. Fisler, and C. H. Warden. 2004. A novel mouse chromosomeomosome 2 congenic strain with obesity phenotypes. Mamm. Genome. 15: 452-459.
    • (2004) Mamm. Genome , vol.15 , pp. 452-459
    • Diament, A.L.1    Farahani, P.2    Chiu, S.3    Fisler, J.4    Warden, C.H.5
  • 23
    • 0032807087 scopus 로고    scopus 로고
    • Quantitative trait loci analysis for the differences in susceptibility to atherosclerosis and diabetes between inbred mouse strains C57BL/6J and C57BLKS/J
    • Mu, J. L., J. K. Naggert, K. L. Svenson, G. B. Collin, J. H. Kim, C. McFarland, P. M. Nishina, D. M. Levine, K. J. Williams, and B. Paigen. 1999. Quantitative trait loci analysis for the differences in susceptibility to atherosclerosis and diabetes between inbred mouse strains C57BL/6J and C57BLKS/J. J. Lipid Res. 40: 1328-1335.
    • (1999) J. Lipid Res. , vol.40 , pp. 1328-1335
    • Mu, J.L.1    Naggert, J.K.2    Svenson, K.L.3    Collin, G.B.4    Kim, J.H.5    McFarland, C.6    Nishina, P.M.7    Levine, D.M.8    Williams, K.J.9    Paigen, B.10
  • 27
    • 0346727152 scopus 로고    scopus 로고
    • Quantitative trait locus analysis of plasma cholesterol and triglyceride levels in KK x RR F2 mice
    • Suto, J., and K. Sekikawa. 2003. Quantitative trait locus analysis of plasma cholesterol and triglyceride levels in KK x RR F2 mice. Biochem. Genet. 41: 325-341.
    • (2003) Biochem. Genet. , vol.41 , pp. 325-341
    • Suto, J.1    Sekikawa, K.2
  • 28
    • 4444293999 scopus 로고    scopus 로고
    • Quantitative trait locus analysis of plasma cholesterol and triglyceride levels in C57BL/6J x RR F2 mice
    • Suto, J., Y. Takahashi, and K. Sekikawa. 2004. Quantitative trait locus analysis of plasma cholesterol and triglyceride levels in C57BL/6J x RR F2 mice. Biochem. Genet. 42: 347-363.
    • (2004) Biochem. Genet. , vol.42 , pp. 347-363
    • Suto, J.1    Takahashi, Y.2    Sekikawa, K.3
  • 29
    • 0030239728 scopus 로고    scopus 로고
    • Sensitivity to dietary obesity linked to a locus on chromosome 15 in a CAST/Ei x C57BL/6J F2 intercross
    • York, B., K. Lei, and D. B. West. 1996. Sensitivity to dietary obesity linked to a locus on chromosome 15 in a CAST/Ei x C57BL/6J F2 intercross. Mamm. Genome. 7: 677-681.
    • (1996) Mamm. Genome , vol.7 , pp. 677-681
    • York, B.1    Lei, K.2    West, D.B.3
  • 30
    • 11844280278 scopus 로고    scopus 로고
    • Genetics of variation in HDL cholesterol in humans and mice
    • Wang, X., and B. Paigen. 2005. Genetics of variation in HDL cholesterol in humans and mice. Circ. Res. 96: 27-42.
    • (2005) Circ. Res. , vol.96 , pp. 27-42
    • Wang, X.1    Paigen, B.2
  • 31
    • 0036738377 scopus 로고    scopus 로고
    • Quantitative trait loci and candidate genes regulating HDL cholesterol: A murine chromosome map. Arterioscler
    • Wang, X., and B. Paigen. 2002. Quantitative trait loci and candidate genes regulating HDL cholesterol: a murine chromosome map. Arterioscler. Thromb. Vasc. Biol. 22: 1390-1401.
    • (2002) Thromb. Vasc. Biol. , vol.22 , pp. 1390-1401
    • Wang, X.1    Paigen, B.2
  • 32
    • 0035207519 scopus 로고    scopus 로고
    • Identification of wound healing/regeneration quantitative trait loci (QTL) at multiple time points that explain seventy percent of variance in (MRL/MpJ and SJL/J) mice F2 population
    • Masinde, G. L., X. Li, W. Gu, H. Davidson, S. Mohan, and D. J. Baylink. 2001. Identification of wound healing/regeneration quantitative trait loci (QTL) at multiple time points that explain seventy percent of variance in (MRL/MpJ and SJL/J) mice F2 population. Genome Res. 11: 2027-2033.
    • (2001) Genome Res. , vol.11 , pp. 2027-2033
    • Masinde, G.L.1    Li, X.2    Gu, W.3    Davidson, H.4    Mohan, S.5    Baylink, D.J.6
  • 34
    • 0042665656 scopus 로고    scopus 로고
    • Quantitative trait loci for bone density in mice: The genes determining total skeletal density and femur density show little overlap in F2 mice
    • Masinde, G. L., X. Li, W. Gu, J. Wergedal, S. Mohan, and D. J. Baylink. 2002. Quantitative trait loci for bone density in mice: the genes determining total skeletal density and femur density show little overlap in F2 mice. Calcif. Tissue Int. 71: 421-428.
    • (2002) Calcif. Tissue Int. , vol.71 , pp. 421-428
    • Masinde, G.L.1    Li, X.2    Gu, W.3    Wergedal, J.4    Mohan, S.5    Baylink, D.J.6
  • 35
    • 0036691518 scopus 로고    scopus 로고
    • Quantitative trait loci that harbor genes regulating muscle size in (MRL/MPJ x SJL/J) F(2) mice
    • Masinde, G. L., X. Li, W. Gu, M. Hamilton-Ulland, S. Mohan, and D. J. Baylink. 2002. Quantitative trait loci that harbor genes regulating muscle size in (MRL/MPJ x SJL/J) F(2) mice. Funct. Integr. Genomics. 2: 120-125.
    • (2002) Funct. Integr. Genomics , vol.2 , pp. 120-125
    • Masinde, G.L.1    Li, X.2    Gu, W.3    Hamilton-Ulland, M.4    Mohan, S.5    Baylink, D.J.6
  • 36
    • 2942537642 scopus 로고    scopus 로고
    • Quantitative trait loci for periosteal circumference (PC): Identification of single loci and epistatic effects in F2 MRL/SJL mice
    • Masinde, G. L., J. Wergedal, H. Davidson, S. Mohan, R. Li, X. Li, and D. J. Baylink. 2003. Quantitative trait loci for periosteal circumference (PC): identification of single loci and epistatic effects in F2 MRL/SJL mice. Bone. 32: 554-560.
    • (2003) Bone , vol.32 , pp. 554-560
    • Masinde, G.L.1    Wergedal, J.2    Davidson, H.3    Mohan, S.4    Li, R.5    Li, X.6    Baylink, D.J.7
  • 37
    • 8444222325 scopus 로고    scopus 로고
    • Mapping quantitative trait loci that influence blood levels of alkaline phosphatase in MRL/MpJ and SJL/J mice
    • Srivastava, A. K., G. Masinde, H. Yu, D. J. Baylink, and S. Mohan. 2004. Mapping quantitative trait loci that influence blood levels of alkaline phosphatase in MRL/MpJ and SJL/J mice. Bone. 35: 1086-1094.
    • (2004) Bone , vol.35 , pp. 1086-1094
    • Srivastava, A.K.1    Masinde, G.2    Yu, H.3    Baylink, D.J.4    Mohan, S.5
  • 38
    • 0035140274 scopus 로고    scopus 로고
    • Concordance of murine quantitative trait loci for salt-induced hypertension with rat and human loci
    • Sugiyama, F., G. A. Churchill, D. C. Higgins, C. Johns, K. P. Makaritsis, H. Gavras, and B. Paigen. 2001. Concordance of murine quantitative trait loci for salt-induced hypertension with rat and human loci. Genomics. 71: 70-77.
    • (2001) Genomics , vol.71 , pp. 70-77
    • Sugiyama, F.1    Churchill, G.A.2    Higgins, D.C.3    Johns, C.4    Makaritsis, K.P.5    Gavras, H.6    Paigen, B.7
  • 40
    • 0034611681 scopus 로고    scopus 로고
    • Genetics of body-weight regulation
    • Barsh, G. S., I. S. Farooqi, and S. O'Rahilly. 2000. Genetics of body-weight regulation. Nature. 404: 644-651.
    • (2000) Nature , vol.404 , pp. 644-651
    • Barsh, G.S.1    Farooqi, I.S.2    O'Rahilly, S.3
  • 41
    • 0030585744 scopus 로고    scopus 로고
    • Detection of obesity QTLs on mouse chromosomes 1 and 7 by selective DNA pooling
    • Taylor, B. A., and S. J. Phillips. 1996. Detection of obesity QTLs on mouse chromosomes 1 and 7 by selective DNA pooling. Genomics. 34: 389-398.
    • (1996) Genomics , vol.34 , pp. 389-398
    • Taylor, B.A.1    Phillips, S.J.2
  • 42
    • 0032887888 scopus 로고    scopus 로고
    • Gender-influenced obesity QTLs identified in a cross involving the KK type II diabetes-prone mouse strain
    • Taylor, B. A., L. M. Tarantino, and S. J. Phillips. 1999. Gender-influenced obesity QTLs identified in a cross involving the KK type II diabetes-prone mouse strain. Mamm. Genome. 10: 963-968.
    • (1999) Mamm. Genome , vol.10 , pp. 963-968
    • Taylor, B.A.1    Tarantino, L.M.2    Phillips, S.J.3
  • 43
    • 0032104113 scopus 로고    scopus 로고
    • Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model
    • Mehrabian, M., P. Z. Wen, J. Fisler, R. C. Davis, and A. J. Lusis. 1998. Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model. J. Clin. Invest. 101: 2485-2496.
    • (1998) J. Clin. Invest. , vol.101 , pp. 2485-2496
    • Mehrabian, M.1    Wen, P.Z.2    Fisler, J.3    Davis, R.C.4    Lusis, A.J.5
  • 45
    • 12444333161 scopus 로고    scopus 로고
    • Identification of a novel lipase gene mutated in lpd mice with hypertriglyceridemia and associated with dyslipidemia in humans
    • Wen, X. Y., R. A. Hegele, J. Wang, D. Y. Wang, J. Cheung, M. Wilson, M. Yahyapour, Y. Bai, L. Zhuang, J. Skaug, et al. 2003. Identification of a novel lipase gene mutated in lpd mice with hypertriglyceridemia and associated with dyslipidemia in humans. Hum. Mol. Genet. 12: 1131-1143.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 1131-1143
    • Wen, X.Y.1    Hegele, R.A.2    Wang, J.3    Wang, D.Y.4    Cheung, J.5    Wilson, M.6    Yahyapour, M.7    Bai, Y.8    Zhuang, L.9    Skaug, J.10
  • 46
    • 0034523871 scopus 로고    scopus 로고
    • Single QTL effects, epistasis, and pleiotropy account for two-thirds of the phenotypic F(2) variance of growth and obesity in DU6i x DBA/2 mice
    • Brockmann, G. A., J. Kratzsch, C. S. Haley, U. Renne, M. Schwerin, and S. Karle. 2000. Single QTL effects, epistasis, and pleiotropy account for two-thirds of the phenotypic F(2) variance of growth and obesity in DU6i x DBA/2 mice. Genome Res. 10: 1941-1957.
    • (2000) Genome Res. , vol.10 , pp. 1941-1957
    • Brockmann, G.A.1    Kratzsch, J.2    Haley, C.S.3    Renne, U.4    Schwerin, M.5    Karle, S.6
  • 47
    • 4644219642 scopus 로고    scopus 로고
    • Haplotype analysis in multiple crosses to identify a QTL gene
    • Wang, X., R. Korstanje, D. Higgins, and B. Paigen. 2004. Haplotype analysis in multiple crosses to identify a QTL gene. Genome Res. 14: 1767-1772.
    • (2004) Genome Res. , vol.14 , pp. 1767-1772
    • Wang, X.1    Korstanje, R.2    Higgins, D.3    Paigen, B.4
  • 48
    • 0037267495 scopus 로고    scopus 로고
    • Multiple cross and inbred strain haplotype mapping of complex-trait candidate genes
    • Park, Y. G., R. Clifford, K. H. Buetow, and K. W. Hunter. 2003. Multiple cross and inbred strain haplotype mapping of complex-trait candidate genes. Genome Res. 13: 118-121.
    • (2003) Genome Res. , vol.13 , pp. 118-121
    • Park, Y.G.1    Clifford, R.2    Buetow, K.H.3    Hunter, K.W.4
  • 49
    • 3042578627 scopus 로고    scopus 로고
    • Haplotype sharing suggests that a genomic segment containing six genes accounts for the pulmonary adenoma susceptibility 1 (Pas1) locus activity in mice
    • Manenti, G., F. Galbiati, R. Gianni-Barrera, A. Pettinicchio, A. Acevedo, and T. A. Dragani. 2004. Haplotype sharing suggests that a genomic segment containing six genes accounts for the pulmonary adenoma susceptibility 1 (Pas1) locus activity in mice. Oncogene. 23: 4495-4504.
    • (2004) Oncogene , vol.23 , pp. 4495-4504
    • Manenti, G.1    Galbiati, F.2    Gianni-Barrera, R.3    Pettinicchio, A.4    Acevedo, A.5    Dragani, T.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.