Synthesis of a potentially bioactive, hydroxyapatite-nucleating molecule

Calcified Tissue International

Volumn 78, Issue 1, 2006, Pages 55-61

  Chang, S ^a   Chen, H ^a   Liu, J ^a   Wood, D ^b   Bentley, P ^b   Clarkson, B ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Human; Hydroxyapatite; Nucleation; Phosphophoryn; Polypeptide

Indexed keywords

ADENOSINE TRIPHOSPHATE; AGAROSE; AMINO ACID; CALCIUM ION; CASEIN KINASE I; CASEIN KINASE II; COMPLEMENTARY DNA; HYDROXYAPATITE; PHOSPHATE; POLYPEPTIDE; RNA;

ADDITION REACTION; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BONE MINERALIZATION; BONE REGENERATION; BONE REMODELING; CALCIUM BINDING; CONTROLLED STUDY; DNA SEQUENCE; GENETIC CODE; HUMAN; HUMAN TISSUE; HYPOTHESIS; LABORATORY; MOLECULAR CLONING; PRECIPITATION; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; STEADY STATE; SYNTHESIS; TOOTH; TRANSMISSION ELECTRON MICROSCOPY; X RAY DIFFRACTION;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; CASEIN KINASE I; CASEIN KINASE II; DNA, COMPLEMENTARY; EXTRACELLULAR MATRIX; HUMANS; HYDROXYAPATITES; MICROSCOPY, ELECTRON; MOLAR; PEPTIDES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN PRECURSORS; TOOTH CALCIFICATION; X-RAY DIFFRACTION;

EID: 30844450579     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00223-005-0118-4     Document Type: Article

References (45)

1. Linde A (1989) Dentin matrix proteins: composition and possible functions in calcification. Anat Rec 224:154-166
2. Veis A (1993) Mineral-matrix interactions in bone and dentin. J Bone Miner Res 8(suppl 2):S493-S497
3. Butler WT, Ritchie H (1995) The nature and functional significance of dentin extracellular matrix proteins. Int J Dev Biol 39:169-179
4. Butler WT, Bhown M, DiMuzio MT, Cothran WC, Linde A (1983) Multiple forms of rat dentin phosphoproteins. Arch Biochem Biophys 225:178-186
5. Takagi Y, Veis A (1984) Isolation of phosphophoryn from human dentin organic matrix. Calcif Tissue Int 36:259-265
6. Chang SR, Chiego D Jr, Clarkson BH (1996) Characterization and identification of a human dentin phosphophoryn. Calcif Tissue Int 59:149-153
7. Nawrot CF, Campbell DJ, Schroeder JK, Van Valkenburg M (1976) Dental phosphoprotein-induced formation of hydroxylapatite during in vitro synthesis of amorphous calcium phosphate. Biochemistry 15:3445-3449
8. 2+- binding studies of the phosphoprotein from rat-incisor dentine. Eur J Biochem 113:541-545
9. Termine JD, Eanes ED, Conn KM (1980) Phosphoprotein modulation of apatite crystallization. Calcif Tissue Int 31:247-251
10. Lussi A, Crenshaw MA, Linde A (1988) Induction and inhibition of hydroxyapatite formation by rat dentine phosphoprotein in vitro. Arch Oral Biol 33:685-691
11. Linde A, Lussi A (1989) Mineral induction by polyanionic dentin and bone proteins at physiological ionic conditions. Connect Tissue Res 21:197-203
12. Boskey AL, Maresca M, Doty S, Sabsay B, Veis A (1990) Concentration-dependent effects of dentin phosphophoryn in the regulation of in vitro hydroxyapatite formation and growth. Bone Miner 11:55-65
13. Hunter GK, Hauschka PV, Poole AR, Rosenberg LC, Goldberg HA (1996) Nucleation and inhibition of hydroxyapatite formation by mineralized tissue proteins. Biochem J 317:59-64
14. D'Souza RN, Cavender A, Sunavala G, Alvarez J, Ohshima T, Kulkarni AB, MacDougall M (1997) Gene expression patterns of murine dentin matrix protein 1 (Dmp1) and dentin sialophosphoprotein (DSPP) suggest distinct developmental functions in vivo. J Bone Miner Res 12:2040-2049
15. George A, Sabsay B, Simonian PA, Veis A (1993) Characterization of a novel dentin matrix acidic phosphoprotein. Implications for induction of biomineralization. J Biol Chem 268:12624-12630
16. He G, Dahl T, Veis A, George A (2003) Dentin matrix protein 1 initiates hydroxyapatite formation in vitro. Connect Tissue Res 44(suppl 1):240-245
17. He G, Dahl T, Veis A, George A (2003) Nucleation of apatite crystals in vitro by self-assembled dentin matrix protein 1. Nat Mater 2:552-558
18. Tartaix PH, Doulaverakis M, George A, Fisher LW, Butler WT, Qin C, Salih E, Tan M, Fujimoto Y, Spevak L, Boskey AL (2004) In vitro effects of dentin matrix protein-1 on hydroxyapatite formation provide insights into in vivo functions. J Biol Chem 279:18115-18120
19. van den Bos T, Steinfort J, Beertsen W (1993) Effect of bound phosphoproteins and other organic phosphates on alkaline phosphatase-induced mineralization of collagenous matrices in vitro. Bone Miner 23:81-93
20. Narayanan K, Ramachandran A, Hao J, He G, Park KW, Cho M, George A (2003) Dual functional roles of dentin matrix protein 1 Implications in biomineralization and gene transcription by activation of intracellular Ca2+ store. J Biol Chem 278:17500-17508
21. Wallwork ML, Kirkham J, Chen H, Chang SX, Robinson C, Smith DA, Clarkson BH (2002) Binding of dentin noncollagenous matrix proteins to biological mineral crystals: an atomic force microscopy study. Calcif Tissue Int 71:249-255
22. Wu CB, Pelech SL, Veis A (1992) The in vitro phosphorylation of the native rat incisor dentin phosphophoryns. J Biol Chem 267:16588-16594
23. Zeichner-David M, Hall F, Williams R, Thiemann F, Yen S, MacDougall M, Slavkin HC (1995) Characterization of protein kinases involved in dentinogenesis. Connect Tissue Res 33:87-95
24. Ritchie HH, Wang LH (1996) Sequence determination of an extremely acidic rat dentin phosphoprotein. J Biol Chem 271:21695-21698
25. n triplet repeat domain of rat dentin phosphophoryn. Eur J Oral Sci 106(suppl 1):234-238
26. George A, Bannon L, Sabsay B, Dillon JW, Malone J, Veis A, Jenkins NA, Gilbert DJ, Copeland NG (1996) The carboxyl-terminal domain of phosphophoryn contains unique extended triplet amino acid repeat sequences forming ordered carboxyl-phosphate interaction ridges that may be essential in the biomineralization process. J Biol Chem 271:32869-32873
27. George A, Srinivasan R, Thotakura S, Veis A (1998) The phosphophoryn gene family: identical domain structures at the carboxyl end. Eur J Oral Sci 106(suppl 1):221-226
28. Thotakura SR, Mah T, Srinivasan R, Takagi Y, Veis A, George A (2000) The non-collagenous dentin matrix proteins are involved in dentinogenesis imperfecta type II (DGI-II). J Dent Res 79:835-839
29. MacDougall M, Simmons D, Luan X, Nydegger J, Feng J, Gu TT (1997) Dentin phosphoprotein and dentin sialoprotein are cleavage products expressed from a single transcript coded by a gene on human chromosome 4. Dentin phosphoprotein DNA sequence determination. J Biol Chem 272:835-842
30. Ritchie H, Wang LH (1997) A mammalian bicistronic transcript encoding two dentin-specific proteins. Biochem Biophys Res Commun 231:425-428
31. Gu K, Chang S, Ritchie HH, Clarkson BH, Rutherford RB (2000) Molecular cloning of a human dentin sialophosphoprotein gene. Eur J Oral Sci 108:35-42
32. Ritchie HH, Berry JE, Somerman MJ, Hanks CT, Bronckers AL, Hotton D, Papagerakis P, Berdal A, Butler WT (1997) Dentin sialoprotein (DSP) transcripts: developmentally-sustained expression in odontoblasts and transient expression in pre-ameloblasts. Eur J Oral Sci 105:405-413
33. Butler WT, Bhown M, Brunn JC, D'Souza RN, Farach-Carson MC, Happonen RP, Schrohenloher RE, Seyer JM, Somerman MJ, Foster RA (1992) Isolation, characterization and immunolocalization of a 53-kDa dentin sialoprotein (DSP). Matrix 12:343-351
34. D'Souza RN, Bronckers AL, Happonen RP, Doga DA, Farach-Carson MC, Butler WT (1992) Developmental expression of a 53 kD dentin sialoprotein in rat tooth organs. J Histochem Cytochem 40:359-366
35. Bronckers AL, Farach-Carson MC, Van Waveren E, Butler WT (1994) Immunolocalization of osteopontin, osteocalcin, and dentin sialoprotein during dental root formation and early cementogenesis in the rat. J Bone Miner Res 9:833-841
36. Boskey A, Spevak L, Tan M, Doty SB, Butler WT (2000) Dentin sialoprotein (DSP) has limited effects on in vitro apatite formation and growth. Calcif Tissue Int 67:472-478
37. Butler WT, Bhown M, DiMuzio MT, Linde A (1981) Non-collagenous proteins of dentin Isolation and partial characterization of rat dentin proteins and proteoglycans using a three-step preparative method. Collagen Relat Res 1:187-199
38. Chen PS, Toribara TY, Warner H (1956) Microdetermination of phosphorus. Anal Chem. 28:1756-1758
39. Leventouri T, Bunaciu CE, Perdikatsis V (2003) Neutron powder diffraction studies of silicon-substituted hydroxyapatite. Biomaterials 24:4205-4211
40. Fujisawa R, Wada Y, Nodasaka Y, Kuboki Y (1996) Acidic amino acid-rich sequences as binding sites of osteonectin to hydroxyapatite crystals. Biochim Biophys Acta 1292:53-60
41. Tye CE, Rattray KR, Warner KJ, Gordon JA, Sodek J, Hunter GK, Goldberg HA (2003) Delineation of the hydroxyapatite-nucleating domains of bone sialoprotein. J Biol Chem 278:7949-7955
42. Hunter GK, Goldberg HA (1993) Nucleation of hydroxyapatite by bone sialoprotein. Proc Natl Acad Sci USA 90:8562-8565
43. Rezania A, Thomas CH, Branger AB, Waters CM, Healy KE (1997) The detachment strength and morphology of bone cells contacting materials modified with a peptide sequence found within bone sialoprotein. J Biomed Mater Res 37:9-19
44. Bearinger JP, Castner DG, Healy KE (1998) Biomolecular modification of p(AAm-co-EG/AA) IPNs supports osteoblast adhesion and phenotypic expression. J Biomater Sci Polym Ed 9:629-652
45. Barber TA, Golledge SL, Castner DG, Healy KE (2003) Peptide-modified p(AAm-co-EG/AAc) IPNs grafted to bulk titanium modulate osteoblast behavior in vitro. J Biomed Mater Res 64A:38-47