Impact of the CYP2D6 metaboliser status on the pupillary response of tramadol - A commentary

European Journal of Clinical Pharmacology

Volumn 62, Issue 1, 2006, Pages 77-78

  Fliegert, F ^a   Kurth, B ^a   Gohler K ^a  

^a GRÜNENTHAL GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2D6; PLACEBO; TRAMADOL;

AREA UNDER THE CURVE; CIRCADIAN RHYTHM; DEVICE; DRUG ABSORPTION; DRUG EFFECT; DRUG FORMULATION; ENANTIOMER; HUMAN; LETTER; LIGHT; METHODOLOGY; MIOSIS; PRIORITY JOURNAL; PUPIL; PUPIL REFLEX; PUPILLOMETRY; SAMPLING;

EID: 30844449029     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-005-0040-8     Document Type: Letter

References (3)

1. Slanar O, Perlik F (2004) CYP2D6 polymorphism and miotic efect of tramadol in healthy volunteers. Drug Metab Rev 36:114
2. Slanar O, Nobilis M, Kvetina J, Idle JR, Perlik F (2005) CYP2D6 polymorphism, tramadol pharmacokinetics and pupillary response. Eur J Clin Pharmacol
3. Knaggs RD, Crighton IM, Cobby TF, Fletcher AJ, Hobbs GJ (2004) The pupillary effects of intravenous morphine, codeine, and tramadol in volunteers. Anesth Analg 99:108-112