The interplay of increased urea synthesis and reduced ammonia production in the african lungfish Protopterus aethiopicus during 46 days of aestivation in a mucus cocoon

Journal of Experimental Zoology Part A: Comparative Experimental Biology

Volumn 303, Issue 12, 2005, Pages 1054-1065

  Yuen, Kwong Ip ^a   Pei, Jia Yeo ^a   Ai, May Loong ^a   Kum, Chew Hiong ^a   Wai, Peng Wong ^a   Shit, Fun Chew ^b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; AMMONIA; UREA;

ADAPTATION; ANIMAL; ARTICLE; BLOOD; BRAIN; COMPARATIVE STUDY; DIET RESTRICTION; FISH; LIVER; METABOLISM; MUSCLE; PHYSIOLOGY; TIME;

AMINO ACIDS; AMMONIA; ANIMALS; BRAIN; ESTIVATION; FASTING; FISHES; LIVER; MUSCLES; TIME FACTORS; UREA;

PROTOPTERUS AETHIOPICUS;

EID: 30744472623     PISSN: 15488969     EISSN: 1552499X     Source Type: Journal    
DOI: 10.1002/jez.a.237     Document Type: Article

References (33)

1. Anderson PM, Little RM. 1986. Kinetic properties of cyanase. Biochemistry 25:1621-1626.
2. Anderson PM, Walsh PJ. 1995. Subcellular localization and biochemical properties of the enzyme carbamoyl phosphate synthetase and urea synthesis in the batrachoidid fishes, Opsanus beta, Opsanus tau and Porichthys notatus. J Exp Biol 198:755-766.
3. Bergmeyer HU, Beutler HO. 1985. Ammonia. In: Bergmeyer HU, Bergmeyer J, Graßl M, editors. Methods of enzymatic analysis, Vol. VIII. New York: Academic Press. p 454-461.
4. Brien P. 1959. Ethologie du Protopterus dolloi (Boulenger) et de ses larves. Signification des sacs pulmonaires des Dipneustes. Ann Soc R Zool Belg 89:9-48.
5. Brusilow SW. 2002. Reviews in molecular medicine - hyperammonemic encephalopathy. Medicine 81:240-249.
6. Campbell JW. 1973. Nitrogen excretion. In: Prosser CL, editor. Comparative animal physiology, 3rd edition. Philadelphia: Saunders College Publishing. p 279-316.
7. Cao XY, Kemp JR, Anderson PM. 1991. Subcellular localization of two glutamine-dependent carbamoyl-phosphate synthetases and related enzymes in liver of Micropterus salmoides (largemouth bass) and properties of isolated liver mitochondria: comparative relationships with elasmobranchs. J Exp Zool 258:24-33.
8. Chew SF, Ong TF, Ho L, Tam WL, Loong AM, Hiong KC, Wong WP, Ip YK. 2003. Urea synthesis in the African lungfish Protopterus dolloi: hepatic carbamoyl phosphate synthetase III and glutamine synthetase are up regulated by 6 days of aerial exposure. J Exp Biol 206:3615-3624.
9. Chew SF, Chan NKY, Tam WL, Loong AM, Hiong KC, Ip YK. 2004. Nitrogen metabolism in the African lungfish (Protopterus dolloi) aestivating in a mucus cocoon on land. J Exp Biol 207:777-786.
10. Chew SF, Tan FO, Ho L, Tam WL, Loong AM, Hiong KC, Ip YK. 2005a. The African Lungfish, Protopterus dolloi, detoxifies ammonia to urea during environmental ammonia exposure. Physiol Biochem Zool 78:31-39.
11. Chew SF, Wilson JM, Ip YK, Randall DJ. 2005b. Ammonia excretion and defence against ammonia toxicity. In: Val A, Almedía-Val V, Randall DJ, editors. Fish physiology, Vol. 21, physiology of tropical fish. New York: Academic Press. p 307-395.
12. Cooper JL, Plum F. 1987. Biochemistry and physiology of brain ammonia. Physiol Rev 67:440-519.
13. Felipo V, Butterworth RF. 2002. Neurobiology of ammonia. Progr Neurobiol 67:259-279.
14. Felskie AK, Anderson PM, Wright PA. 1998. Expression and activity of carbamoyl phosphate synthetase III and ornithine-urea cycle enzymes in various tissues of four fish species. Comp Biochem Physiol 119B:355-364.
15. Graham JB. 1997. Air-breathing fishes: evolution, diversity and adaptation. London: Academic Press.
16. Hermenegildo C, Marcaida G, Montoliu C, Grisolia S, Minana M, Felipo V. 1996. NMDA receptor antagonists prevent acute ammonia toxicity in mice. Neurochem Res 21:1237-1244.
17. Ip YK, Chew SF, Randall DJ. 2001. Ammonia toxicity, tolerance and excretion. In: Wright PA, Anderson PM, editors. Fish physiology, Vol. 20, nitrogen excretion. New York: Academic Press. p 109-148.
18. Ip YK, Chew SF, Randall DJ. 2004a. Five tropical air-breathing fishes, six different strategies to defend against ammonia toxicity on land. Physiol Biochem Zool 77:768-782.
19. Ip YK, Chew SF, Wilson JM, Randall DJ. 2004b. Defences against ammonia toxicity in tropical air-breathing fishes exposed to high concentrations of environmental ammonia: a review. J Comp Physiol B 174:555-564.
20. 4Cl+urea on nitrogen excretion and metabolism in the African lungfish Protopterus dolloi. J Exp Zool 303A:272-282.
21. Janssens PA. 1964. The metabolism of the aestivating African lungfish. Comp Biochem Physiol 11:105-117.
22. Janssens PA, Cohen PP. 1968a. Biosynthesis of urea in the estivating African lungfish and in Xenopus laevis under conditions of water shortage. Comp Biochem Physiol 24:887-898.
23. Janssens PA, Cohen PP. 1968b. Nitrogen metabolism in the African lungfish. Comp Biochem Physiol 24:879-886.
24. Jow LY, Chew SF, Lim CB, Anderson PM, Ip YK. 1999. The marble goby Oxyeleotris marmoratus activates hepatic glutamine synthetase and detoxifies ammonia to glutamine during air exposure. J Exp Biol 202:237-245.
25. Lim CK, Wong WP, Lee SML, Chew SF, Ip YK. 2004. The ammonotelic African lungfish, Protopterus dolloi, increases the rate of urea synthesis and becomes ureotelic after feeding. J Comp Physiol B 174:555-564.
26. Loong AM, Hiong KC, Lee SML, Wong WP, Chew SF, Ip YK. 2005. Ornithine-urea cycle and urea synthesis in African lungfishes, Protopterus aethiopicus and Protopterus annectens, exposed to terrestrial conditions for 6 days. J Exp Zool 303A:366-376.
27. Mommsen TP, Walsh PJ. 1989. Evolution of urea synthesis in vertebrates: the piscine connection. Science 243:72-75.
28. Poll M. 1961. Révision systématique et raciation géographique des Protopteridae de l'Afrique centrale. Ann Mus R Afr Centr série in-8° Sci Zool 103:3-50.
29. Rose C. 2002. Increased extracellular brain glutamate in acute liver failure: decreased uptake or increased release? Metab Brain Dis 17:251-261.
30. Shankar RA, Anderson PM. 1985. Purification and properties of glutamine synthetase from the liver of Squalus acanthias. Arch Biochem Biophys 239:248-259.
31. Smith HW. 1935. The metabolism of the lungfish II. Effect of feeding meat on metabolic rate. J Cell Comp Physiol 6:335-349.
32. Wood CM, Walsh PJ, Chew SF, Ip YK. 2005. Greatly elevated urea excretion after air-exposure appears to be carrier-mediated in the slender lungfish (Protopterus dolloi). Physiol Biochem Zool, in press.
33. Xiong X, Anderson PM. 1989. Purification and properties of ornithine carbamoyl transferase from the liver of Squalus acanthias. Arch Biochem Biophys 270:198-207.