Evaluation of a recombinant human adenovirus-5 vaccine administered via needle-free device and intramuscular injection for vaccination of pigs against swine influenza virus

American Journal of Veterinary Research

Volumn 66, Issue 11, 2005, Pages 1943-1947

  Wesley, Ronald D ^a   Lager, Kelly M ^a  

^a NATIONAL ANIMAL DISEASE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEMAGGLUTINATION INHIBITING ANTIBODY; HEMAGGLUTININ; HISTONE H3; INFLUENZA VACCINE; VIRUS NUCLEOPROTEIN;

ANIMAL EUTHANASIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; CLINICAL OBSERVATION; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; DRUG SAFETY; HUMAN ADENOVIRUS 5; INFLUENZA VACCINATION; INJECTION; INOCULATION; LUNG DISEASE; LUNG EXAMINATION; LUNG LAVAGE; NEEDLE; NONHUMAN; NOSE SECRETION; PROVOCATION TEST; SEROCONVERSION; STATISTICAL SIGNIFICANCE; SWINE DISEASE; SWINE INFLUENZA VIRUS; VIRAL GENE DELIVERY SYSTEM; VIRUS RECOMBINANT; VIRUS REPLICATION; VIRUS SHEDDING; VIRUS TRANSMISSION; WEANING;

ADENOVIRIDAE; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; HEMAGGLUTINATION INHIBITION TESTS; HEMAGGLUTININS, VIRAL; INFLUENZA A VIRUS, H3N2 SUBTYPE; INFLUENZA VACCINES; INJECTIONS, INTRAMUSCULAR; ORTHOMYXOVIRIDAE INFECTIONS; SPECIFIC PATHOGEN-FREE ORGANISMS; SWINE; SWINE DISEASES; VACCINATION; VACCINES, SYNTHETIC; VIRUS REPLICATION;

ADENOVIRIDAE; ANIMALIA; HUMAN ADENOVIRUS TYPE 5; SUS SCROFA; SWINE INFLUENZA VIRUS;

EID: 30744472156     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.2005.66.1943     Document Type: Article

References (22)

1. Olsen CW. The emergence of novel swine influenza viruses in North America. Virus Res 2002;85:199-210.
2. Choi YK, Goyal SM, Joo HS. Prevalence of swine influenza subtypes on swine farms in the United States. Arch Virol 2002;147:1209-1220.
3. Larsen DL, Karasin A, Zuckermann F, et al. Systemic and mucosal immune responses to H1N1 influenza virus infection in pigs. Vet Microbiol 2000;74:117-131.
4. Janke BH. Classic swine influenza. Large Anim Pract 1998;19:24-29.
5. Easterday BC, Van Reeth K. Swine influenza. In: Straw BE, D'Allaire S, Mengeling WL, Taylor DJ, eds. Diseases of swine. 8th ed. Ames, Iowa: Iowa State University Press, 1999;277-290.
6. Vannier P. Infectious causes of abortion in swine. Reprod Domest Anim 1999;34:367-376.
7. Webby RJ, Swenson SL, Krauss SL, et al. Evolution of swine H3N2 influenza viruses in the United States. J Virol 2000;74:8243-8251.
8. Karasin AI, Olsen CW, Anderson GA. Genetic characterization of an H1N2 influenza virus isolated from a pig in Indiana. J Clin Microbiol 2000;38:2453-2456.
9. Choi YK, Goyal SM, Farnham MW, et al. Phylogenetic analysis of H1N2 isolates of influenza A virus from pigs in the United States. Virus Res 2002;87:173-179.
10. Thacker B, Kruse F, Loskutoc A. Safety evaluation of a modified live pseudorabies virus vaccine administered using a needle-free, transdermal injection device, in Proceedings. 34th Annu Meet Am Assoc Swine Vet 2003;87-88.
11. Cook DL, Kruse F, Demontis G. Pulse 200 effective application method for swine influenza vaccine in sows, in Proceedings. 4th Int Symp Emerg Re-emerging Pig Dis 2003;279.
12. Almond GW, Roberts JD. Practical application for a needle-less injection device, in Proceedings. 18th Int Pig Vet Soc Cong 2004;842.
13. Tang M, Harp JA, Wesley RD. Recombinant adenovirus encoding the HA gene from swine H3N2 influenza virus partially protects mice from challenge with heterologous virus: A/HK/1/68 (H3N2). Arch Virol 2002;147:2125-2141.
14. Wesley RD, Tang M, Lager KM. Protection of weaned pigs by vaccination with human adenovirus 5 recombinant viruses expressing the hemagglutinin and the nucleoprotein of H3N2 swine influenza virus. Vaccine 2004;22:3427-3434.
15. Mengeling WL, Vorwald AC, Lager KM, et al. Diagnosis of porcine reproductive and respiratory syndrome using infected alveolar macrophages collected from live pigs. Vet Microbiol 1996;49:105-115.
16. Palmer DF, Dowdle WR, Coleman MT, et al. Advanced laboratory techniques for influenza diagnosis. Immunology series No. 6. Washington, DC: US Department of Health, Education, and Welfare, 1975;51-52.
17. Mumford JA. Equine influenza. In: Manual of standards for diagnostic tests and vaccines. Paris: OIE, 1996;409-419.
18. Specter S, Lancz GJ. Clinical virology manual. New York: Elsevier, 1986;193-195.
19. Eloit M. Defective adenoviruses as virus vectors for veterinary vaccines. Vet Res 1995;26:207-208.
20. Heinen PP, van Nieuwstadt AP, de Boer-Luijtze EA, et al. Analysis of the quality of protection induced by a porcine influenza A vaccine to challenge with an H3N2 virus. Vet Immunol Immunopathol 2001;82:39-56.
21. LePotier MF, Monteil M, Houdayer C, et al. Study of the delivery of the gD gene of pseudorabies virus to one-day-old piglets by adenovirus or plasmid DNA as ways to bypass the inhibition of immune response by colostral antibodies. Vet Microbiol 1997;55:75-80.
22. Wesley RD, Lager KM. A recombinant Ad-5 swine influenza vaccine that overrides maternal antibody interference, in Proceedings. 35th Annu Meet Am Assoc Swine Vet 2004;447-449.