In vitro effect of leptin on growth hormone (GH)- and insulin-like growth factor-I (IGF-I)-stimulated progesterone secretion and apoptosis in developing and mature corpora lutea of pig ovaries

Journal of Reproduction and Development

Volumn 51, Issue 6, 2005, Pages 727-733

  Gregoraszczuk, Ewa Łucja ^a   Ptak, Anna ^a  

^a JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

Caspase 3 activity; Corpus luteum; Growth hormone (GH); Insulin like growth factor I (IGF I); Pig; Progesterone

Indexed keywords

CASPASE; CASPASE 3; GROWTH HORMONE; LEPTIN; PROGESTERONE; SOMATOMEDIN C;

ANIMAL; APOPTOSIS; ARTICLE; CELL CULTURE; CORPUS LUTEUM; CYTOLOGY; DRUG EFFECT; DRUG INTERACTION; ESTRUS CYCLE; FEMALE; IN VITRO STUDY; METABOLISM; OVARY; PHYSIOLOGY; SECRETION; SWINE;

ANIMALS; APOPTOSIS; CASPASE 3; CASPASES; CELLS, CULTURED; CORPUS LUTEUM; DRUG INTERACTIONS; ESTROUS CYCLE; FEMALE; GROWTH HORMONE; INSULIN-LIKE GROWTH FACTOR I; LEPTIN; OVARY; PROGESTERONE; SUS SCROFA;

SUS SCROFA;

EID: 30744466439     PISSN: 09168818     EISSN: 13484400     Source Type: Journal    
DOI: 10.1262/jrd.17038     Document Type: Article

References (24)

1. Ruiz-Cortes ZT, Men T, Palin MF, Downey BR, Lacroix DA, Murphy BD. Porcine leptin receptor: molecular structure and expression in the ovary. Mol Reprod Dev 2000; 56: 465-474.
2. Ruiz-Cortes ZT, Martel-Kennes Y, Gevry NY, Downey BR, Palin MF, Murphy BD. Biphasic effects of leptin in porcine granulosa cells. Biol Reprod 2003; 68: 789-796.
3. Hardie L, Trayhurn P, Abramovich D, Fowler P. Circulating leptin in women: a longitudinal study in the menstrual cycle and during pregnancy. Clin Endocrinol 1997; 47: 101-106.
4. Gregoraszczuk EL, Ptak A, Wojtowicz AK, Gorska T, Nowak KW. Estrus cycle-dependent action of leptin on basal and GH or IGF-I stimulated steroid secretion by whole porcine follicles. Endocr Regul 2004; 38: 15-21.
5. Almog B, Gold R, Tajima K, Dantes A, Salim K, Rubinstein M, Barkan D, Homburg R, Lessing JB, Nevo N, Gertler A, Amsterdam A. Leptin attenuates follicular apoptosis and accelerates the onset of puberty in immature rats. Mol Cell Endocrinol 2001; 183: 179-191.
6. Herman A, Helman D, Livnah O, Gertler A. Ruminant placental lactogens act as antagonists to homologous growth hormone receptors and as agonists to human or rabbit growth hormone receptors. J Biol Chem 1999; 274: 7631-7639.
7. Peri I, Shamay A, McGrath MF, Collier RJ, Gertler A. Comparative mitogenic and galactopoietic effects of IGF-I, IGF-II and Des-3-IGF-I in bovine mammary gland in vitro. Cell Biol Int Rep 1992; 16: 359-368.
8. Fine M, Amuly R, Sandowski Y, Marchant TA, Chan SJ, Gertler A, Funkenstein B. Recombinant gilthead seabream (Sparus aurata) insulin-like growth factor-I: subcloning, expression in Escherichia coli, purification and characterization. J Endocrinol 1997; 153: 139-150.
9. Gertler A, Simmons J, Keisler DH. Large-scale preparation of biologically active recombinant ovine obese protein (leptin). FEBS Lett 1998; 422: 137-140.
10. Gregoraszczuk EL, Wojtusiak A. Evaluation of the physiological value of porcine luteal cells isolated in various stages of the luteal phase: tissue culture approach. Cytotechnology 1992; 8: 215-217.
11. Gregoraszczuk E. Steroid hormone release in cultures of pig corpus luteum and granulosa cells: effect of LH, hCG, PRL and estradiol. Endocrinol Exp 1983; 17: 59-68.
12. Okuda K, Uenoyama Y, Fujita Y, Iga K, Sakamoto K, Kimura T. Functional oxytocin receptors in bovine granulosa cells. Biol Reprod 1997; 56: 625-631.
13. Gregoraszczuk EL, Wojtowicz AK, Ptak A, Nowak K. In vitro effect of leptin on steroids' secretion by FSH- and LH-treated porcine small, medium and large preovulatory follicles. Reprod Biol 2003; 3: 227-239.
14. Duggal PS, Van Der Hoek KH, Milner CR, Ryan NK, Armstrong DT, Magoffin DA, Norman RJ. The in vivo and in vitro effects of exogenous leptin on ovulation in the rat. Endocrinology 2000; 141: 1971-1976.
15. Spicer LJ, Chamberlain CS, Francisco CC. Ovarian action of leptin: effects on insulin-like growth factor-I-stimulated function of granulosa and thecal cells. Endocrine 2000; 12: 53-59.
16. Spicer LJ, Francisco CC. The adipose obese gene product, leptin: evidence of a direct inhibitory role in ovarian function. Endocrinology 1997; 138: 3374-3379.
17. Spicer LJ, Francisco CC. Adipose obese gene product, leptin, inhibits bovine ovarian thecal cell steroidogenesis. Biol Reprod 1998; 58: 207-212.
18. Tajima K, Orisaka M, Hosokawa K, Amsterdam A, Kotsuji F. Effects of ovarian theca cells on apoptosis and proliferation of granulosa cells: changes during bovine follicular maturation. Biol Reprod 2002; 66: 1635-1639.
19. Loffler S, Aust G, Kohler U, Spanel-Borowski K. Evidence of leptin expression in normal and polycystic human ovaries. Mol Hum Reprod 2001; 7: 1143-1149.
20. Ptak A, Gregoraszczuk EL, Rzasa J. Growth hormone and insulin-like growth factor-I action on progesterone secretion by porcine corpora lutea isolated at various periods of the luteal phase. Acta Vet Hung 2003; 51: 197-208.
21. Gadsby JE, Lovdal JA, Samaras S, Barber JS, Hammond JM. Expression of the messenger ribonucleic acids for insulin-like growth factor-I and insulin-like growth factor binding proteins in porcine corpora lutea. Biol Reprod 1996; 54: 339-346.
22. Nicholson WC, Ge Z, Plotner DM, Farin CE, Gadsby JE. Insulin-like growth factor (IGF)-I, IGF-I receptor, and IGF binding protein-3 messenger ribonucleic acids and protein in corpora lutea from prostaglandin F2α-treated gilts. Biol Reprod 1999; 61: 1527-1534.
23. Ge Z, Miller E, Nicholson W, Hedgpeth V, Gadsby J. Insulin-like growth factor (IGF)-I and IGF binding proteins-2, -3, -4, -5 in porcine corpora lutea during the estrous cycle; evidence for inhibitory actions of IGFBP-3. Domest Anim Endocrinol 2003; 25: 183-197.
24. Brannian JD, Zhao Y, McElroy M. Leptin inhibits gonadotrophin-stimulated granulosa cell progesterone production by antagonizing insulin action. Hum Reprod 1999; 14: 1445-1448.