Effect of hydroxypropyl cellulose (HPC) on dissolution rate of hydrochlorothiazide tablets

International Journal of Pharmaceutics

Volumn 308, Issue 1-2, 2006, Pages 40-45

  Desai, D ^a   Rinaldi, F ^a   Kothari, S ^a   Paruchuri, S ^a   Li, D ^a,b   Lai, M ^a,c   Fung, S ^a,d   Both, D ^a  

^a BRISTOL MYERS SQUIBB   (United States)

^b BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

^c ARRAY BIOPHARMA INC   (United States)

^d JANSSEN RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Binder; Cloud point; Dissolution; Excipient; HPC; Hydroxypropoxy substitution; Hydroxypropyl cellulose

Indexed keywords

HYDROCHLOROTHIAZIDE; HYDROXYPROPYLCELLULOSE;

ARTICLE; DISSOLUTION; DRUG ANALYSIS; DRUG EFFECT; DRUG FORMULATION; DRUG POTENCY; DRUG SOLUBILITY; DRUG STRUCTURE; HYDROPHILICITY; MOLECULAR WEIGHT; PRIORITY JOURNAL; TABLET; VISCOSITY;

CELLULOSE; COMPRESSIVE STRENGTH; DIURETICS; EXCIPIENTS; HYDROCHLOROTHIAZIDE; SOLUBILITY; TABLETS; TEMPERATURE; TIME FACTORS;

EID: 30744466420     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2005.10.011     Document Type: Article

References (3)

1. 13C-NMR spectral and related studies on the distribution of substitutents into (2-hydroxypropyl) cellulose Carbohydrate Res. 106 1982 1 19
2. E.D. Klug Some properties of water-soluble hydroxyalkyl celluloses and their derivatives J. Polymer Sci. 36 1971 491 508
3. J.W. Stafford, J.F. Pickard, and R. Zink Temperature dependence of the disintegration times of compressed tablets containing hydroxypropylcellulose as binder J. Pharm. Pharmac. 30 1978 1 5