Protective effects of ulinastatin on the lung injury during cardiopulmonary bypass

Journal of Central South University (Medical Sciences)

Volumn 30, Issue 6, 2005, Pages 670-672

  Wang, Dian Jun ^a,b   Liu, Jian Xin ^a   Yin, Bang Liang ^b  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Cardiopulmonary bypass; Lung injury; Polymorphonuclear neutrophil elastase; Ulinastatin

Indexed keywords

LEUKOCYTE ELASTASE; MALONALDEHYDE; OXYGEN RADICAL; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA; ULINASTATIN;

ARTICLE; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; HUMAN; LUNG INJURY; LUNG LAVAGE; MALE; PREOPERATIVE PERIOD; RESPIRATORY TRACT INFLAMMATION; RHEUMATIC HEART DISEASE;

ADOLESCENT; ADULT; AGED; BRONCHOALVEOLAR LAVAGE FLUID; CARDIOPULMONARY BYPASS; FEMALE; GLYCOPROTEINS; HUMANS; LEUKOCYTE ELASTASE; MALE; MIDDLE AGED; PROTECTIVE AGENTS; RESPIRATORY DISTRESS SYNDROME, ADULT; RHEUMATIC HEART DISEASE; TRYPSIN INHIBITORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 30744449967     PISSN: 16727347     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Cao ZL, Okazaki Y, Naito K, et al. Ulinastatin attenuates reperfusion injury in the isolated blood-perfued rabbit heart[J]. Ann Thorac Surg, 2000, 69(4):1121-1126.
2. Wang HS, Yi DH, Wang ZW, et al. Protective effects of L-arginine against lung injury during cardiopulmonary bypass[J]. J Fourth Milit Med Univ, 1998, 19(4):429-431.
3. Te Velthuis H, Jansen PG, Oudemans-van Straaten HM, et al. Myocardial performance in eldly patients after cardiopulmonary bypass is suppressed by tumor necrosis factor[J]. J Thorac Cardiovasc Surg, 1995, 110(6):1663-1669.
4. Ohkawa F, Ikeda U, Kanbe T, et al. Effects of inflammatory cytokines on vascular tone[J]. Cardiovasc Res, 1995, 30(5):711-715.
5. Hyers TM, Tricomi SM, Dettenmeier PA, et al. Tumor necrosis factor levels in serum and brochoalveolar lavage fluid of patients with the adult respiratory distress syndrome[J]. Am Rev Respir Dis. 1991, 144(2):268-271.
6. Tsuji C, Shioya S. In vivo effect of methylprednisolone on lipopolysaccharide induced superoxide production by pulmonary and circulating blood neutrophils in rats[J]. Circ Shock, 1994, 42(3): 128-134.
7. Jansen NJ, Van Oeveren W, Gu YJ, et al. Endotoxin release and tumor necrosis factor formation during cardiopulmonary bypass[J]. Ann Thorac Surg, 1992, 54(4):744-748.