Subacute demyelinating polyneuropathy in B-cell lymphoma with IgM antibodies against glycolipid GD1b

Neurological Sciences

Volumn 26, Issue 5, 2005, Pages 355-357

  Marfia, Girolama A ^a   Pachatz, C ^a   Terracciano, C ^a   Leone, G ^a   Bernardini, S ^b   Bernardi, G ^a,c   Massa, R ^a,c  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c IRCCS FONDAZIONE SANTA LUCIA   (Italy)

Author keywords

B cell lymphoma; Gangliosides; GD1b; Monoclonal gammopathy; Paraproteinaemic neuropathies

Indexed keywords

ANTINEOPLASTIC AGENT; AUTOANTIBODY; GANGLIOSIDE GD 1B; GANGLIOSIDE GM1; GANGLIOSIDE GQ 1B ANTIBODY; GLYCOLIPID; IMMUNOGLOBULIN; IMMUNOGLOBULIN M ANTIBODY; MYELIN ASSOCIATED GLYCOPROTEIN; PARAPROTEIN; PREDNISONE;

AGED; ANTIBODY TITER; ARTICLE; ATAXIA; B CELL LYMPHOMA; CANCER GRADING; CASE REPORT; DEMYELINATING NEUROPATHY; DISEASE ASSOCIATION; FEMALE; HUMAN; HUMAN CELL; LIMB DISEASE; LYMPHOMA CELL; MONOCLONAL IMMUNOGLOBULINEMIA; MOTOR DYSFUNCTION; NONHODGKIN LYMPHOMA; PAIN; PARAPROTEINEMIA; PARESTHESIA; POLYNEUROPATHY; RECTUM TUMOR; SENSORIMOTOR NEUROPATHY; SENSORY DYSFUNCTION;

AGED; DEMYELINATING DISEASES; FEMALE; GANGLIOSIDES; HUMANS; IMMUNOGLOBULIN M; LYMPHOMA, B-CELL; POLYNEUROPATHIES;

EID: 30744449755     PISSN: 15901874     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10072-005-0500-z     Document Type: Article

References (13)

1. Smith IS, Kahn SN, Lacy BW et al (1983) Chronic demyelinating neuropathy associated with benign IgM paraproteinemia. Brain 106:169-195
2. Ropper AH, Kenneth CG (1998) Neuropathies associated with paraproteinemia. N Engl J Med 338:1601-1607
3. Willison HJ, Yuki N (2002) Peripheral neuropathies and anti-glycolipid antibodies. Brain 125:2591-2625
4. Nobile-Orazio E, Manfredini E, Carpo M et al (1994) Frequency and clinical correlates of anti-neural IgM antibodies in neuropathy associated with IgM monoclonal gammopathy. Ann Neurol 36:416-424
5. Eurelings M, Notermans NC, Van De Donk NW, Lokhorst HM (2001) Risk factors for hematological malignancy in polyneuropathy associated with monoclonal gammopathy. Muscle Nerve 24:1295-1302
6. Daune GC, Farrer RG, Dalakas MC, Quarles RH (1992) Sensory neuropathy associated with monoclonal immunoglobulin M to GD1b ganglioside. Ann Neurol 31:683-685
7. Younes-Chennoufi AB, Leger JM, Hauw JJ et al (1992) Ganglioside GD1b is the target antigen for a biclonal IgM in a case of sensory-motor axonal polyneuropathy: Involvement of N-acetylneuraminic acid in the epitope. Ann Neurol 32:18-23
8. Miyazaki T, Kusunoki S, Kaida K et al (2001) Guillain-Barré syndrome associated with IgG monospecific to ganglioside GD1b. Neurology 56:1227-1229
9. Eurelings M, Ang CW, Notermans NC et al (2001) Antiganglioside antibodies in polyneuropathy associated with monoclonal gammopathy. Neurology 57:1909-1912
10. Kusunoki S, Chiba A, Tai T, Kanazawa I (1993) Localization of GM1 and GD1b antigens in the human peripheral nervous system. Muscle Nerve 16:752-756
11. Kusunoki S, Shimizu J, Chiba et al (1996) Experimental sensory neuropathy induced by sensitization with ganglioside GD1b. Ann Neurol 39:424-431
12. Kusunoki S, Mashiko H, Mochizuki N et al (1997) Binding of antibodies against GM1 and GD1b in human peripheral nerve. Muscle Nerve 20:840-845
13. Noguchi M, Mori K, Yamazaki S et al (2003) Multifocal motor neuropathy caused by a B-cell lymphoma producing a monoclonal IgM autoantibody against peripheral nerve myelin glycolipids GM1 and GD1b. Br J Haematol 123:600-605