Hinge peptide combinatorial libraries for inhibitors of botulinum neurotoxins and saxitoxin: Deconvolution strategy

Molecular Diversity

Volumn 10, Issue 1, 2006, Pages 9-16

  Moore, Graham J ^a,b   Moore, Diana M ^a   Roy, Samir S ^a,c   Hayden, Lawrence J ^d   Hamilton, Murray G ^e   Chan, Nora W C ^f   Lee, William E ^f  

^a PepMetics Inc   (Canada)

^b UNIVERSITY OF VICTORIA   (Canada)

^c UNIVERSITY OF CALGARY   (Canada)

^d Harvest Research Associates   (United States)

^e UNIVERSITY OF DENVER   (United States)

^f DEFENCE RESEARCH AND DEVELOPMENT CANADA   (Canada)

Author keywords

Botulinum neurotoxin; Combinatorial; Deconvolution strategy; Hinge peptide libraries; Saxitoxin

Indexed keywords

4 AMINOBUTYRIC ACID; AMINO ACID; BOTULINUM TOXIN A; BOTULINUM TOXIN B; CAPTOPRIL; OUABAIN; PEPTIDE; PROTEINASE; SAXITOXIN; UNCLASSIFIED DRUG; VERATRIDINE; ZINC PROTEASE;

ANIMAL CELL; ARTICLE; BIOASSAY; BIOMECHANICS; CARBOXY TERMINAL SEQUENCE; COMBINATORIAL LIBRARY; CONTROLLED STUDY; ENZYME ACTIVITY; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE;

BIOLOGICAL ASSAY; BOTULINUM TOXIN TYPE A; BOTULINUM TOXINS; CELL SURVIVAL; COMBINATORIAL CHEMISTRY TECHNIQUES; ENZYME INHIBITORS; HUMANS; LIGANDS; METALLOENDOPEPTIDASES; NEUROBLASTOMA; OUABAIN; PEPTIDE FRAGMENTS; PEPTIDE LIBRARY; PROTEASE INHIBITORS; SAXITOXIN; VERATRIDINE; ZINC;

EID: 30744431863     PISSN: 13811991     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11030-006-1394-2     Document Type: Article

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