Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocytes

Genetics and Molecular Biology

Volumn 27, Issue 3, 2004, Pages 460-466

  Figueiredo, André B S ^a   Alves, Rex N ^a   Ramalho, Adriana T ^b  

^a MILITARY INSTITUTE OF ENGINEERING   (Brazil)

^b INSTITUTO DE PESQUISAS ENERGÉTICAS E NUCLEARES   (Brazil)

Author keywords

Chromosomal aberrations; Human lymphocytes; Microwaves

Indexed keywords

ARTICLE; BLOOD CELL; CELL MEMBRANE; CELL STRUCTURE; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CONTROLLED STUDY; GAMMA IRRADIATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTE CULTURE; MICROWAVE RADIATION; MONITORING; MORBIDITY; MORTALITY; RADIATION DOSE; RADIATION EXPOSURE; RADIOSENSITIVITY; STATISTICAL SIGNIFICANCE;

EID: 30644474627     PISSN: 14154757     EISSN: 16784685     Source Type: Journal    
DOI: 10.1590/S1415-47572004000300024     Document Type: Article

References (37)

1. Alam MT, Barthakur N, Lambert NG and Kasatiya SS (1978) Cytological effects of microwave radiation in Chinese hamster cells in vitro. Can J Genet Cytol 20:23-28.
2. Balode Z (1996) Assessment of radio-frequency electromagnetic radiation by the micronucleus test in bovine peripheral erythrocytes. Sci Total Environ 180:81-86.
3. 1/2 cells and exposure to a 836.55 MHz modulated radiofrequency field. Bioelectromagnetics 18:237-243.
4. Ciaravino V, Meltz ML and Erwin DN (1987) Effects of radiofrequency radiation and simultaneous exposure with mytomicin C on the frequency of sister chromatid exchanges in Chinese hamster ovary cells. Environ Mutagen 9:393-398.
5. Ciaravino V, Meltz ML and Erwin DN (1991) Absence of a synergistic effect between moderate-power-radiofrequency electromagnetic radiation and adriamycin on cell-cycle progression and sister-chromatid exchange. Bioelectromagnetics 12:289-294.
6. Garaj-Vrhovac V and Fucic A (1993) The rate of elimination of chromosomal aberrations after accidental exposure to microwave radiation. Bioelectrochem Bioenerg 30:319-325.
7. Garaj-Vrhovac V, Fucic A and Horvat D (1992) The correlation between the frequency of micronuclei and specific aberrations in human lymphocytes exposed to microwave radiation in vitro. Mutat Res 281:181-186.
8. Garaj-Vrhovac V, Horvat D and Koren Z (1991) The relationship between colony-forming ability, chromosome aberrations and incidence of micronuclei in V79 Chinese hamster cells exposed to microwave radiation. Mutat Res 263:143-149.
9. Goswami PC, Albee LD, Parsian AJ, Baty JD, Moros EG, Pickard WF, Roti Roti JL and Hunt CR (1999) Proto-oncogene mRNA levels and activities of multiple transcription factors in C3H 10T 1/2 murine embryonic fibroblasts exposed to 835.62 and 847.74 MHz cellular telephone communication frequency radiation. Radiat Res 151:300-309.
10. Haidler T, Knasmueller S, Kundi M and Haidler M (1994) Clastogenic effects of radiofrequency radiations on chromosomes of Tradescantia. Mutat Res 324:65-71.
11. IAEA (2001) International Atomic Energy Agency. Cytogenetic Analysis for Radiation Dose Assessment: A Manual. Technical Report Series 405, Vienna, 127 pp.
12. ICNIRP (1998) International Committee on Non Ionising Radiation Protection. Guidelines for limiting exposure to time-varying electric, magnetic, and electromagnetic fields (up to 300 GHz). Health Phys 74:494-522.
13. IEGMP (2000) Independent Expert Group on Mobile Phones. Mobile Phones and Health. NRPB publication, Chilton, UK, 159 pp.
14. Ivaschuk OI, Jones RA, Ishida-Jones T, Haggren Q, Adey WR and Phillips JL (1997) Exposure of nerve growth factor-treated PC12 rat pheochromocytoma cells to a modulated radiofrequency field at 836.55 MHz: Effects on c-jun and c-fos expression. Bioelectromagnetics 18:223-229.
15. Kerbacher JJ, Meltz ML and Erwin DN (1990) Influence of radiofrequency radiation on chromosome aberrations in CHO cells and its interaction with DNA-damaging agents. Radiat Res 123:311-317.
16. Lai H and Singh NP (1995) Acute low-intensity microwave exposure increases DNA single-strand breaks in rat brain cells. Bioelectromagnetics 16:207-210.
17. Lai H and Singh NP (1996) Single- and double-strand DNA breaks in rat brain cells after acute exposure to radiofrequency electromagnetic radiation. Int J Radiat Biol 69:513-521.
18. 0 human lymphocytes. Int J Radiat Biol 46:135-141.
19. Lloyd DC, Saunders RD, Moquet JE and Kowalczuk CI (1986) Absence of chromosomal damage in human lymphocytes exposed to microwave radiation with hyperthermia. Bioelectromagnetics 7:235-240.
20. Maes A, Collier M, van Gorp U, Vandoninck S and Verschaeve L (1997) Cytogenetic effects of 935.2-MHz (GSM) microwaves alone and in combination with mitomycin C. Mutat Res 393:151-156.
21. Maes A, Collier M and Verschaeve L (2001) Cytogenetic effects of 900 MHz (GSM) microwaves on human lymphocytes. Bioelectromagnetics 22:91-96.
22. Maes A, Verschaeve L, Arroyo A, de Wagner C and Vercruyssen L (1993) In vitro cytogenetic effects of 2450 MHz waves on human peripheral blood lymphocytes. Bioelectromagnetics 14:495-501.
23. Meltz ML, Eagan P and Erwin DN (1989) Absence of mutagenic interaction between microwaves and mitomycin C in mammalian cells. Environ Mol Mutagen 13:294-299.
24. Meltz ML, Eagan P and Erwin DN (1990) Proflavin and microwave radiation: Absence of a mutagenic interaction. Bioelectromagnetics 11:149-154.
25. Meltz ML, Walker KA and Erwin DN (1987) Radiofrequency (microwave) radiation exposure of mammalian cells during UV-induced DNA repair synthesis. Radiat Res 110:255-260.
26. OECD (1997) Organisation for Economic Cooperation and Development. OECD Guidelines for the Testing of Chemicals, Guideline 473: In vitro Mammalian Chromosome Aberration Test, Paris, 10 pp.
27. Pakhomova ON, Pakhomov AG and Akyel Y (1997) Effect of millimeter waves on UV-induced recombination and mutagenesis in yeast. Bioelectrochem Bioenerg 43:227.
28. Phillips JL, Ivaschuk O, Ishida-Jones T, Jones RA, Campbell-Beachler M and Haggnen W (1998) DNA damage in molt-4 T-lymphoblastoid cells exposed to cellular telephone radiofrequency fields in vitro. Bioelectrochem Bioenerg 45:103-110.
29. Sagripanti J and Swicord ML (1986) DNA structural changes caused by microwave radiation. Int J of Radiat Biol 50:47-50.
30. Sarkar S, Ali S and Behari J (1994) Effect of low power microwave on the mouse genome: A direct DNA analysis. Mutat Res 320:141-147.
31. Scarf MR, Lioi MB, dÁmbrosio G, Massa R, Zeni O, De pietro R and De Berardino D (1996) Genotoxic effects of mytomicin-C and microwave radiation on bovine lymphocytes. Electro-Magnetobiology 15:99-104.
32. Szmigielski S, Szudzinski A, Pietraszek A, Bielec M and Wrembel JK (1982) Accelerated development of spontaneous and benzopyrene-induced skin cancer in mice exposed to 2450-MHz microwave-radiation. Bioelectromagnetics 3:179-185.
33. Tice R, Hook ± and McRee DI (1999) Chromosome aberrations from exposure to cell phone radiation. Microwave News 7-8:7.
34. Timchenko OI and Ianchevskaia NV (1995) The cytogenetic action of electromagnetic fields in the short-wave range. Psychopharmacol Ser 7-8:37-39.
35. Verschaeve L, Slaets D, Van Gorp U, Maes A and Vanderkom J (1994) In vitro and in vivo genetic effects of microwaves from mobile phone frequencies in human and rat peripheral blood lymphocytes. Proceedings of Cost 244 Meetings on Mobile Communication and Extremely Low Frequency Field: Instrumentation and Measurements in Bioelectromagnetics Research. D. Simunic (ed), Information Ventures Inc., Plzen, Chech Republic, pp 74-83.
36. Vijayalaxmi BZ, Frei MR, Dusch SJ, Guel V, Meltz ML and Jauchem JR (1997) Frequency of micronuclei in the peripheral blood and bone marrow of cancer-prone mice chronically exposed to 2450 MHz radiofrequency radiation. Radiat Res 147:495-500.
37. Wolff S, James TL, Young GB, Margulis AR, Bodycote J and Afzal V (1985). Magnetic resonance imaging: Absence of in vitro cytogenetic damage. Radiology 155:163-169.