Minimal ovarian upregulation of glutamate cysteine ligase expression in response to suppression of glutathione by buthionine sulfoximine

Reproductive Toxicology

Volumn 21, Issue 2, 2006, Pages 186-196

  Hoang, Yvonne D ^a   Avakian, Ani P ^a   Luderer, Ulrike ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Buthionine sulfoximine; Gamma glutamylcysteine synthetase; Glutamate cysteine ligase; Glutathione; Ovary

Indexed keywords

BUTHIONINE SULFOXIMINE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; MESSENGER RNA; PROTEIN SUBUNIT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME REGULATION; ESTRUS; FEMALE; GRANULOSA CELL; HORMONAL REGULATION; HORMONE ACTION; HORMONE DETERMINATION; HORMONE INHIBITION; HORMONE SYNTHESIS; METESTRUS; NONHUMAN; NUCLEOTIDE SEQUENCE; OVARY FOLLICLE; PROESTRUS; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; UPREGULATION;

ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; BUTHIONINE SULFOXIMINE; CELLS, CULTURED; ENZYME INHIBITORS; ESTRADIOL; ESTROUS CYCLE; FEMALE; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; GRANULOSA CELLS; IN SITU HYBRIDIZATION; ORGAN SIZE; OVARY; PROGESTERONE; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; UP-REGULATION;

ANIMALIA;

EID: 30644473111     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reprotox.2005.07.011     Document Type: Article

References (44)

1. M.E. Anderson, and J.L. Luo Glutathione therapy: from prodrugs to genes Semin Liver Dis 18 1998 415 424
2. D.R. Mattison, K. Shiromizu, J.A. Pendergrass, and S.S. Thorgeirsson Ontogeny of ovarian glutathione and sensitivity to primordial oocyte destruction by cyclophosphamide Pediatr Pharmacol 3 1983 49 55
3. N. Clague, M. Sevcik, G. Stuart, M. Brännström, P.O. Janson, and J.F. Jarrell The effect of estrous cycle and buthionine sulfoximine on glutathione release from the in vitro perfused rat ovary Reprod Toxicol 6 1992 533 539
4. U. Luderer, T.J. Kavanagh, C.C. White, and E.M. Faustman Gonadotropin regulation of glutathione synthesis in the rat ovary Reprod Toxicol 15 2001 495 504
5. S.G. Lopez, and U. Luderer Effects of cyclophosphamide and buthionine sulfoximine on ovarian glutathione and apoptosis Free Radic Biol Med 36 2004 1366 1377
6. M. Tsai-Turton, and U. Luderer The effect of glutathione depletion by buthionine sulfoximine (BSO) on apoptosis in cultured antral follicles 2005 The Endocrine Society San Diego, CA Abstract #P2:251 presented at ENDO 2005
7. J.L. Tilly, and K.I. Tilly Inhibitors of oxidative stress mimic the ability of follicle-stimulating hormone to suppress apoptosis in cultured rat ovarian follicles Endocrinology 136 1995 242 252
8. S.M. Deneke, and B.L. Fanburg Regulation of cellular glutathione Am J Physiol 257 1989 L163 L173
9. O.W. Griffith Biologic and pharmacologic regulation of mammalian glutathione synthesis Free Radic Biol Med 27 1999 922 935
10. S.R. Soltaninassab, K.R. Sekhar, M.J. Meredith, and M.L Freeman Multi-faceted regulation of γ-Glutamylcysteine synthetase J Cell Physiol 182 2000 163 170
11. O.W. Griffith, and R.T. Mulcahy The enzymes of glutathione synthesis: gamma-glutamylcysteine synthetase Adv Enzymol Relat Areas Mol Biol 73 1999 209 267
12. C.-S. Huang, L.-S. Chang, M.E. Anderson, and A. Meister Catalytic and regulatory properties of the heavy subunit of rat kidney γ- Glutamylcysteine synthetase J Biol Chem 268 1993 19675 19680
13. E.L. Dahl, and R.T. Mulcahy Cell-type specific differences in glutamate cysteine ligase transcriptional regulation demonstrate independent subunit control Toxicol Sci 61 2001 265 272
14. U. Luderer, D. Diaz, E.M. Faustman, and T.J. Kavanagh Localization of glutamate cysteine ligase subunit mRNA within the rat ovary and relationship to follicular atresia Mol Reprod Dev 65 2003 254 261
15. M. Tsai-Turton, and U. Luderer Gonadotropin regulation of glutamate cysteine ligase catalytic and modifier subunit expression in the rat ovary is subunit and follicle stage-specific Am J Physiol 289 2005 E391 E402
16. O.W. Griffith Mechanism of action, metabolism, and toxicity of buthionine sulfoximine and its higher homologs, potent inhibitors of glutathione synthesis J Biol Chem 257 1982 13704 13712
17. L. Tian, M.M. Shi, and H.J. Forman Increased transcription of the regulatory subunit of γ-glutamylcysteine synthetase in rat lung epithelial L2 cells exposed to oxidative stress of glutathione depletion Arch Biochem Biophys 342 1997 126 133
18. J. Cai, Z.-Z. Huang, and S.C. Lu Differential regulation of γ-Glutamylcysteine synthetase heavy and light subunit gene expression Biochem J 326 1997 167 172
19. Z.A. Huang, H. Yang, C. Chen, Z. Zeng, and S.C. Lu Inducers of gamma-glutamylcysteine synthetase and their effects on glutathione synthetase expression Biochim Biophys Acta 1493 2000 48 55
20. W.A. Solis, T.P. Dalton, M.Z. Dieter, S. Freshwater, J.M. Harrer, and L. He Glutamate-cysteine ligase modifier subunit: mouse Gclm gene structure and regulation by agents that cause oxidative stress Biochem Pharmacol 63 2002 1739 1754
21. N.R. Kitteringham, H. Powell, Y.N. Clement, C.C. Dodd, J.N. Tettey, and M. Pirmohamed Hepatocellular response to chemical stress in CD-1 mice: induction of early genes and gamma-glutamylcysteine synthetase Hepatology 32 2000 321 333
22. NRC, Guide for the Care and Use of Laboratory Animals. Washington, DC: National Research Council, National Academy of Sciences; 1996.
23. G.J. Krinke The laboratory rat 2000 Academic Press San Diego
24. D.T. Armstrong Hormonal control of uterine lumen fluid retention in the rat Am J Physiol 214 1968 764 771
25. C.A.M. van den Berg-Bakker, A. Hegemeijer, A. Franken-Meijer, E.M. Franken-Postma, V.T.H.B.M. Smit, and P.J.K. Kuppen Establishment and characterization of 7 ovarian carcinoma cell lines and one granulosa tumor cell line: growth features and cytogenetics Int J Cancer 53 1993 613 620
26. H. Zhang, M. Vollmer, M. De Geyter, Y. Litzistorf, A. Ladewig, and M. Dürrenberger Characterization of an immortalized human granulosa cell line (COV434) Mol Human Reprod 6 2000 146 153
27. I.J. Gonzalez-Robayna, T.N. Alliston, P. Buse, G.L. Firestone, and J.S. Richards Functional and subcellular changes in the A-kinase-signaling pathway: relation to aromatase and Sgk expression during the transition of granulosa cells to luteal cells Mol Endocrinol 13 1999 1318 1337
28. S.L. Fitzpatrick, and J.S. Richards Regulation of cytochrome P450 aromatase messenger ribonucleic acid and activity by steroids and gonadotropins in rat granulosa cells Endocrinology 129 1991 1452 1462
29. L.L. Reid, D. Botta, J. Shao, F.N. Hudson, and T.J. Kavanagh Molecular cloning and sequencing of the cDNA encoding mouse glutamate-cysteine ligase regulatory subunit Biochim Biophys Acta 1353 1997 107 110
30. L.L. Reid, D. Botta, Y. Lu, E.P. Gallagher, and T.J. Kavanagh Molecular cloning and sequencing of the cDNA encoding the catalytic subunit of mouse glutamate-cysteine ligase Biochim Biophys Acta 26 1997 233 237
31. S.A. Thompson, C.C. White, C.M. Krejsa, D. Diaz, J.S. Woods, and D.L. Eaton Induction of glutamate-cysteine ligase (γ-Glutamylcysteine synthetase) in the brains of adult female mice subchronically exposed to methylmercury Toxicol Lett 110 1999 1 9
32. C.C. White, H. Viernes, C.M. Kresja, D. Botta, and T.J. Kavanagh Fluorescence-based microtiter plate assay for glutamate-cysteine ligase activity Anal Biochem 318 2003 175 180
33. Wilcox JN, Gee CE, Roberts JL. In situ cDNA:mRNA hybridization: development of a technique to measure mRNA levels in individual cells. In: Conn PM, editor. Neuroendocrine Peptides. New York: Academic Press; 1986. p. 510-33.
34. Y. Kang, X. Qiao, O. Jurma, B. Knusel, and J.K. Andersen Cloning/brain localization of mouse glutamylcysteine synthetase heavy chain mRNA NeuroReport 8 1998 2053 2060
35. S. Li, S.A. Thompson, T.J. Kavanagh, and J.S. Woods Localization by in situ hybridization of gamma-glutamylcysteine synthetase mRNA expression in rat kidney following acute methylmercury treatment Toxicol Appl Pharmacol 141 1996 59 67
36. Plowchalk DR, Smith BJ, Mattison DR. Assessment of toxicity to the ovary using follicle quantitation and morphometrics. In: Heindel JJ, Chapin RE, editors. Female Reproductive Toxicology. San Diego, CA: Academic Press; 1993. p. 57-68.
37. T. Pedersen, and H. Peters Proposal for a classification of oocytes in the mouse ovary J Reprod Fertil 17 1968 555 557
38. B.S. Pasternack, and R.E. Shore Analysis of dichotomous response data from toxicological experiments involving stable laboratory mouse populations Biometrics 38 1982 1057 1067
39. S.K. Stover, G.A. Gushansky, J.J. Salmen, and C.S. Gardiner Regulation of γ-Glutamate cysteine ligase expression by oxidative stress in the mouse preimplantation embryo Toxicol Appl Pharmacol 168 2000 153 159
40. J.M. Hansen, E. Lee, and C. Harris Spatial activities and induction of glutamate-cysteine ligase (GCL) in the postimplantation rat embryo and visceral yolk sac Toxicol Sci 81 2004 371 378
41. M.P. Gamcsik, M.E. Dolan, B.S. Andersson, and D. Murray Mechanisms of resistance to the toxicity of cyclophosphamide Curr Pharm Des 5 1999 587 605
42. B. Jernström, M. Funk, H. Frank, B. Mannervik, and A. Seidel Glutathione-S-transferase A1-1-catalysed conjugation of bay and fjord region diol epoxides of polycyclic aromatic hydrocarbons with glutathione Carcinogenesis 17 1996 1491 1498
43. A. Seidel, T. Friedberg, B. Löllman, A. Schwierzok, M. Funk, and H. Frank Detoxification of optically active bay- and fjord-region polycyclic aromatic hydrocarbon dihydrodiol epoxides by human glutathione transferase P1-1 expressed in chinese hamster V79 cells Carcinogenesis 19 1998 1975 1981
44. P.J. Devine, I.G. Sipes, and P.B. Hoyer Effect of 4-vinylcyclohexene diepoxide dosing in rats on GSH levels in liver and ovaries Toxicol Sci 62 2001 315 320