메뉴 건너뛰기




Volumn 51, Issue 2, 2005, Pages 215-227

ERK pathway inhibitor U0126 induces gamma-globin expression in erythroid cells

Author keywords

ERK; Fetal hemoglobin; Gamma globin; Sickle cell disease; U0126

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; GAMMA GLOBIN; HEMOGLOBIN F; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2;

EID: 30644469601     PISSN: 01455680     EISSN: 1165158X     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (10)

References (78)
  • 1
    • 0028884033 scopus 로고
    • PD98059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
    • Alessi, D.R., Cuenda, A., Cohen, P., Dudley, D.T. and Saltiel, A.R., PD98059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 1995, 270: 27489-27494.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27489-27494
    • Alessi, D.R.1    Cuenda, A.2    Cohen, P.3    Dudley, D.T.4    Saltiel, A.R.5
  • 2
    • 0025363266 scopus 로고
    • Induced differentiation of K562 leukemia cells: A model for studies of gene expression in early megakaryoblasts
    • Alitalo, R., Induced differentiation of K562 leukemia cells: a model for studies of gene expression in early megakaryoblasts. Leuk. Res. 1990, 14: 501-514.
    • (1990) Leuk. Res. , vol.14 , pp. 501-514
    • Alitalo, R.1
  • 3
    • 0027332537 scopus 로고
    • Tyrphostin-induced inhibition of p210bcr-abl tyrosine kinase activity induces K562 to differentiate
    • Anafi, M., Gazit, A., Zehavi, A., Ben-Neriah, Y. and Levitzki, A., Tyrphostin-induced inhibition of p210bcr-abl tyrosine kinase activity induces K562 to differentiate. Blood 1993, 82: 3524-3529.
    • (1993) Blood , vol.82 , pp. 3524-3529
    • Anafi, M.1    Gazit, A.2    Zehavi, A.3    Ben-Neriah, Y.4    Levitzki, A.5
  • 5
    • 11144220892 scopus 로고    scopus 로고
    • A sustained and pancellular reversal of gamma-globin gene silencing in adult human erythroid precursor cells
    • Bhanu, N.Y., Trice, T.A, Lee, Y.T., Gantt, N.M., Oneal, P., Schwartz, J.D., Noel, P. and Miller, J.L., A sustained and pancellular reversal of gamma-globin gene silencing in adult human erythroid precursor cells. Blood 2005, 105: 387-393.
    • (2005) Blood , vol.105 , pp. 387-393
    • Bhanu, N.Y.1    Trice, T.A.2    Lee, Y.T.3    Gantt, N.M.4    Oneal, P.5    Schwartz, J.D.6    Noel, P.7    Miller, J.L.8
  • 8
    • 0026667736 scopus 로고
    • Induced cell surface expression of functional alpha 2 beta 1 integral during megakaryocytic differentiation of K562 leukemic cells
    • Burger, S.R., Zutter, M.M., Sturgill-Koszycki, S. and Santoro, S.A., Induced cell surface expression of functional alpha 2 beta 1 integral during megakaryocytic differentiation of K562 leukemic cells. Exp. Cell Res. 1992, 202: 28-35.
    • (1992) Exp. Cell Res. , vol.202 , pp. 28-35
    • Burger, S.R.1    Zutter, M.M.2    Sturgill-Koszycki, S.3    Santoro, S.A.4
  • 10
    • 0024280908 scopus 로고
    • Developmental regulation of beta-globin gene switching
    • Choi, O.R. and Engel, J.D., Developmental regulation of beta-globin gene switching. Cell 1988, 55: 17-26.
    • (1988) Cell , vol.55 , pp. 17-26
    • Choi, O.R.1    Engel, J.D.2
  • 11
  • 12
    • 0031869466 scopus 로고    scopus 로고
    • Selective induction of apoptosis in Philadelphia chromosome-positive chronic myelogenous leukemia cells by the inhibitor of BCR-ABL tyrosine kinase
    • Dan, S., Maito, M. and Tsurup, T., Selective induction of apoptosis in Philadelphia chromosome-positive chronic myelogenous leukemia cells by the inhibitor of BCR-ABL tyrosine kinase. Cell. Death Differ. 1998, 5: 710-715.
    • (1998) Cell. Death Differ. , vol.5 , pp. 710-715
    • Dan, S.1    Maito, M.2    Tsurup, T.3
  • 14
    • 0027165150 scopus 로고
    • The mitogen-activated protein kinase signal transduction pathway
    • Davis, R.J., The mitogen-activated protein kinase signal transduction pathway. J. Biol. Chem. 1993, 268: 14553-14556.
    • (1993) J. Biol. Chem. , vol.268 , pp. 14553-14556
    • Davis, R.J.1
  • 15
    • 1642458226 scopus 로고    scopus 로고
    • The MEK-1/ERKs signaling pathway is differentially involved in the self-renewal of early and late avian erythroid progenitor cells
    • Dazy S., Damiola, F., Parisey N., Beug, H. and Gandrillon, O., The MEK-1/ERKs signaling pathway is differentially involved in the self-renewal of early and late avian erythroid progenitor cells. Oncogene 2003, 22: 9205-9216.
    • (2003) Oncogene , vol.22 , pp. 9205-9216
    • Dazy, S.1    Damiola, F.2    Parisey, N.3    Beug, H.4    Gandrillon, O.5
  • 16
    • 0036625004 scopus 로고    scopus 로고
    • Maintenance of elevated fetal hemoglobin levels by decitabine during dose interval treatment of sickle cell anemia
    • DeSimone, J., Koshy, M., Dorn, L., Lavelle, D., Bressler, L., Molokie, R. and Talischy, N., Maintenance of elevated fetal hemoglobin levels by decitabine during dose interval treatment of sickle cell anemia. Blood 2002, 99: 3905-3908.
    • (2002) Blood , vol.99 , pp. 3905-3908
    • DeSimone, J.1    Koshy, M.2    Dorn, L.3    Lavelle, D.4    Bressler, L.5    Molokie, R.6    Talischy, N.7
  • 17
    • 0019333039 scopus 로고
    • In vitro transcription of chromatin containing histones hyperacetylated in vivo
    • Dobson, M.E. and Ingram, V.M., In vitro transcription of chromatin containing histones hyperacetylated in vivo. Nucl. Acids Res. 1980, 8: 4201-4219.
    • (1980) Nucl. Acids Res. , vol.8 , pp. 4201-4219
    • Dobson, M.E.1    Ingram, V.M.2
  • 18
    • 0021927659 scopus 로고
    • 5-Azacytidine increases HbF production and reduces anemia in sickle cell disease: Dose-response analysis of subcutaneous and oral dosage regimens
    • Dover, G.J., Charache, S., Boyer, S.H., Vogelsang, G. and Moyer, M., 5-Azacytidine increases HbF production and reduces anemia in sickle cell disease: dose-response analysis of subcutaneous and oral dosage regimens. Blood 1985, 66: 527-532.
    • (1985) Blood , vol.66 , pp. 527-532
    • Dover, G.J.1    Charache, S.2    Boyer, S.H.3    Vogelsang, G.4    Moyer, M.5
  • 22
    • 0030854855 scopus 로고    scopus 로고
    • γ-Globin gene silencing in primary erythroid cultures: An inhibitory role for interleukin-6
    • Ferry, A., Baliga, S., Monterio, C., Chen, Y. and Pace, B.S., γ-Globin gene silencing in primary erythroid cultures: an inhibitory role for interleukin-6. J. Biol. Chem. 1997, 272: 20030-20037.
    • (1997) J. Biol. Chem. , vol.272 , pp. 20030-20037
    • Ferry, A.1    Baliga, S.2    Monterio, C.3    Chen, Y.4    Pace, B.S.5
  • 24
    • 12444285810 scopus 로고    scopus 로고
    • Role of the BMK1/ERK5 signaling pathway: Lessons from knockout mice
    • Hayashi, M. and Lee, J.D., Role of the BMK1/ERK5 signaling pathway: lessons from knockout mice. J. Mol. Med. 2004, 82: 800-808.
    • (2004) J. Mol. Med. , vol.82 , pp. 800-808
    • Hayashi, M.1    Lee, J.D.2
  • 25
    • 2342455050 scopus 로고    scopus 로고
    • Zileuton induces hemoglobin F synthesis in erythroid progenitors: Role of 12-lipoxygenase and nitric oxide
    • Haynes, J.H., Baliga, B.S., Obiako, B., Ofori-Acquah, S.F. and Pace, B.S., Zileuton induces hemoglobin F synthesis in erythroid progenitors: role of 12-lipoxygenase and nitric oxide. Blood 2004, 103: 3945-3950.
    • (2004) Blood , vol.103 , pp. 3945-3950
    • Haynes, J.H.1    Baliga, B.S.2    Obiako, B.3    Ofori-Acquah, S.F.4    Pace, B.S.5
  • 26
    • 0035852675 scopus 로고    scopus 로고
    • Mechanism for fetal globin gene expression: Role of the soluble guanylate cyclase-cGMP-dependent protein kinase pathway
    • Ikuta, T., Ausenda, S. and Cappellini, M.D., Mechanism for fetal globin gene expression: role of the soluble guanylate cyclase-cGMP-dependent protein kinase pathway. Proc. Natl. Acad. Sci. USA 2001, 98: 1847-1852.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 1847-1852
    • Ikuta, T.1    Ausenda, S.2    Cappellini, M.D.3
  • 27
    • 0032054723 scopus 로고    scopus 로고
    • Signal transduction by the c-jun N-terminal kinase (JNK)-from inflammation to development
    • Ip, Y.T. and Davis, R.J., Signal transduction by the c-jun N-terminal kinase (JNK)-from inflammation to development. Curr. Opin. Cell Biol. 1998, 10: 205-219.
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 205-219
    • Ip, Y.T.1    Davis, R.J.2
  • 28
    • 0034254515 scopus 로고    scopus 로고
    • JNK and p38 are activated by erythropoietin (EPO) but are not induced in apoptosis following EPO withdrawal in EPO-dependent HCD57 cells
    • Jacobs-Helber, S.M., Ryan, J.J. and Sawyer, S.T., JNK and p38 are activated by erythropoietin (EPO) but are not induced in apoptosis following EPO withdrawal in EPO-dependent HCD57 cells. Blood 2000, 96: 933-940.
    • (2000) Blood , vol.96 , pp. 933-940
    • Jacobs-Helber, S.M.1    Ryan, J.J.2    Sawyer, S.T.3
  • 29
    • 1642359699 scopus 로고    scopus 로고
    • Raf-1 is not required for megakaryocytopoiesis or TPO-induced ERK phosphorylation
    • Kamata, T., Pritchard, C.A. and Leavitt, A.D., Raf-1 is not required for megakaryocytopoiesis or TPO-induced ERK phosphorylation. Blood 2004, 103: 2568-2570.
    • (2004) Blood , vol.103 , pp. 2568-2570
    • Kamata, T.1    Pritchard, C.A.2    Leavitt, A.D.3
  • 31
    • 0004334206 scopus 로고
    • Cells lines and clinical isolates derived from Ph1-positive chronic myelogenous leukemia patients express c-abl protein with a common structural alteration
    • Knopka, J., Watanabe, S., Singer, J., Collins, S. and Witte, O., Cells lines and clinical isolates derived from Ph1-positive chronic myelogenous leukemia patients express c-abl protein with a common structural alteration. Proc. Natl. Acad. Sci. USA 1985, 82: 1810-1814.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 1810-1814
    • Knopka, J.1    Watanabe, S.2    Singer, J.3    Collins, S.4    Witte, O.5
  • 32
    • 0036072924 scopus 로고    scopus 로고
    • Ras/Raf signaling and emerging pharmacotherapeutic targets
    • Kolch, W., Ras/Raf signaling and emerging pharmacotherapeutic targets. Exp. Opin. Pharmacother. 2002, 3: 709-718.
    • (2002) Exp. Opin. Pharmacother. , vol.3 , pp. 709-718
    • Kolch, W.1
  • 33
    • 0025908209 scopus 로고
    • Negative regulation of globin gene expression during megakaryocytic differentiation of a human erythroleukemic cell line
    • Lumelsky, N.L. and Forget, B.G., Negative regulation of globin gene expression during megakaryocytic differentiation of a human erythroleukemic cell line. Mol. Cell. Biol. 1991, 11: 3528-3536.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 3528-3536
    • Lumelsky, N.L.1    Forget, B.G.2
  • 35
    • 0028007336 scopus 로고
    • Activation of the mouse cytokeratin A (endo A) gene in teratocarcinoma F9 cells by the histone deacetylase inhibitor Trichostatin A
    • Miyashita, T., Yamamoto, H., Nishimune, Y., Nozaki, M., Morita, T. and Matsushiro, A., Activation of the mouse cytokeratin A (endo A) gene in teratocarcinoma F9 cells by the histone deacetylase inhibitor Trichostatin A. FEBS. Lett. 1994, 353: 225-229.
    • (1994) FEBS. Lett. , vol.353 , pp. 225-229
    • Miyashita, T.1    Yamamoto, H.2    Nishimune, Y.3    Nozaki, M.4    Morita, T.5    Matsushiro, A.6
  • 36
    • 0033178564 scopus 로고    scopus 로고
    • Requirement of activation of JNK and p38 for environmental stress-induced erythroid differentiation and apoptosis and of inhibition of ERK for apoptosis
    • Nagata, Y. and Todokoro, K., Requirement of activation of JNK and p38 for environmental stress-induced erythroid differentiation and apoptosis and of inhibition of ERK for apoptosis. Blood 1999, 94: 853-863.
    • (1999) Blood , vol.94 , pp. 853-863
    • Nagata, Y.1    Todokoro, K.2
  • 37
    • 0032530921 scopus 로고    scopus 로고
    • Activation of p38 MAP kinase and JNK but not ERK is required for erythropoietin induced erythroid differentiation
    • Nagata, Y., Takahashi, N., Davis, R.J. and Todokoro, K., Activation of p38 MAP kinase and JNK but not ERK is required for erythropoietin induced erythroid differentiation. Blood 1998, 92: 1859-1869.
    • (1998) Blood , vol.92 , pp. 1859-1869
    • Nagata, Y.1    Takahashi, N.2    Davis, R.J.3    Todokoro, K.4
  • 38
    • 0027382269 scopus 로고
    • Conservation and reiteration of a kinase cascade
    • Neiman, A.M., Conservation and reiteration of a kinase cascade. Trends Genet. 1993, 9: 390-394.
    • (1993) Trends Genet. , vol.9 , pp. 390-394
    • Neiman, A.M.1
  • 39
    • 0026578183 scopus 로고
    • Extracellular signal-regulated kinases in T cells: Characterization of human ERK1 and ERK2 cDNAs
    • Owaki, H., Makar, R., Boulton, T.G., Cobb, M.H. and Geppert, T.D., Extracellular signal-regulated kinases in T cells: characterization of human ERK1 and ERK2 cDNAs. Biochem. Biophys. Res. Commun. 1992, 182: 1416-1422.
    • (1992) Biochem. Biophys. Res. Commun. , vol.182 , pp. 1416-1422
    • Owaki, H.1    Makar, R.2    Boulton, T.G.3    Cobb, M.H.4    Geppert, T.D.5
  • 40
    • 0028265442 scopus 로고
    • Transgenic mouse model of pharmacologic induction of fetal hemoglobin: Studies using a new ribonucleotide reductase inhibitor, Didox
    • Pace, B.S., Elford, H. and Stamatoyannopoulos, G., Transgenic mouse model of pharmacologic induction of fetal hemoglobin: studies using a new ribonucleotide reductase inhibitor, Didox. Am. J. Hematol. 1994, 45: 136-141.
    • (1994) Am. J. Hematol. , vol.45 , pp. 136-141
    • Pace, B.S.1    Elford, H.2    Stamatoyannopoulos, G.3
  • 42
    • 0037114756 scopus 로고    scopus 로고
    • Short chain fatty acid derivatives induce fetal globin expression and erythropoiesis in vivo
    • Pace, B.S., White, G.I., Dover, G.J., Boosalis, M.S., Thies, A. and Perrine, S.P., Short chain fatty acid derivatives induce fetal globin expression and erythropoiesis in vivo. Blood 2002, 100: 4640-4648.
    • (2002) Blood , vol.100 , pp. 4640-4648
    • Pace, B.S.1    White, G.I.2    Dover, G.J.3    Boosalis, M.S.4    Thies, A.5    Perrine, S.P.6
  • 43
    • 0034789188 scopus 로고    scopus 로고
    • Involvement of p38 Kinase in hydroxyurea-induced differentiation of K562 cells
    • Park, J.I., Choi, H.S., Jeong, J.S., Han, J.Y. and Kim, I.H., Involvement of p38 Kinase in hydroxyurea-induced differentiation of K562 cells. Cell. Growth Differ. 2001, 12: 481-486.
    • (2001) Cell. Growth Differ. , vol.12 , pp. 481-486
    • Park, J.I.1    Choi, H.S.2    Jeong, J.S.3    Han, J.Y.4    Kim, I.H.5
  • 44
    • 0034997845 scopus 로고    scopus 로고
    • Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions
    • Pearson, G., Robinson, F., Gibson, T., Xu, B.E., Karandikar, M., Berman, K and Cobb, M.H., Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr. Rev. 2001, 22: 153-183.
    • (2001) Endocr. Rev. , vol.22 , pp. 153-183
    • Pearson, G.1    Robinson, F.2    Gibson, T.3    Xu, B.E.4    Karandikar, M.5    Berman, K.6    Cobb, M.H.7
  • 46
    • 0037370573 scopus 로고    scopus 로고
    • Hemoglobin switching: New insights
    • Peterson, K.R., Hemoglobin switching: new insights. Curr. Opin. Hematol. 2003, 10: 123-129.
    • (2003) Curr. Opin. Hematol. , vol.10 , pp. 123-129
    • Peterson, K.R.1
  • 47
    • 0034765001 scopus 로고    scopus 로고
    • Activation of extracellular signal-regulated kinases potentiates hemin toxicity in astrocyte cultures
    • Regan, R.F., Wang, Y., Ma, X., Chong, A. and Guo, Y., Activation of extracellular signal-regulated kinases potentiates hemin toxicity in astrocyte cultures. J. Neurochem. 2001, 79: 545-555.
    • (2001) J. Neurochem. , vol.79 , pp. 545-555
    • Regan, R.F.1    Wang, Y.2    Ma, X.3    Chong, A.4    Guo, Y.5
  • 48
    • 0017767153 scopus 로고
    • N-butyrate causes histone modification in HeLa and Friend erythroleukemia cells
    • Riggs, M.G., Whittaker, R.G., Neuman, R.G. and Ingram, V.M., N-butyrate causes histone modification in HeLa and Friend erythroleukemia cells. Nature 1977, 268: 462-464.
    • (1977) Nature , vol.268 , pp. 462-464
    • Riggs, M.G.1    Whittaker, R.G.2    Neuman, R.G.3    Ingram, V.M.4
  • 49
    • 0030898417 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways
    • Robinson, M.J. and Cobb, M.H., Mitogen-activated protein kinase pathways. Curr. Opin. Cell Biol. 1997, 9: 180-186.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 180-186
    • Robinson, M.J.1    Cobb, M.H.2
  • 50
    • 2942530310 scopus 로고    scopus 로고
    • ERK and p38 MAPK-activated protein kinases: A family of protein kinases with diverse biological functions
    • Roux, P.P. and Blenis, J., ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. Microbiol. Mol. Biol. Rev. 2004, 68: 320-344.
    • (2004) Microbiol. Mol. Biol. Rev. , vol.68 , pp. 320-344
    • Roux, P.P.1    Blenis, J.2
  • 52
    • 0037220351 scopus 로고    scopus 로고
    • Cyclosporin A induces erythroid differentiation of K562 cells through p38 MAPK and ERK pathways
    • Sawafuji, K., Miyakawa, Y., Kizaki, M. and Ikeda, Y., Cyclosporin A induces erythroid differentiation of K562 cells through p38 MAPK and ERK pathways. Am. J. Hematol. 2003, 72: 67-69.
    • (2003) Am. J. Hematol. , vol.72 , pp. 67-69
    • Sawafuji, K.1    Miyakawa, Y.2    Kizaki, M.3    Ikeda, Y.4
  • 53
    • 0242572080 scopus 로고    scopus 로고
    • Opposite effects of inhibitors of mitogen-activated protein kinase pathways on the erg-1 and β-globin expression in erythropoietin-responsive murine erythroleukemia cells
    • Schaefer, A., Kosa, F., Bittorf, T., Magocsi, M., Rosche, A., Ramirez-Chavez, Y., Morotzki, S. and Marquardt, H., Opposite effects of inhibitors of mitogen-activated protein kinase pathways on the erg-1 and β-globin expression in erythropoietin-responsive murine erythroleukemia cells. Cell. Sig. 2004, 16: 223-234.
    • (2004) Cell. Sig. , vol.16 , pp. 223-234
    • Schaefer, A.1    Kosa, F.2    Bittorf, T.3    Magocsi, M.4    Rosche, A.5    Ramirez-Chavez, Y.6    Morotzki, S.7    Marquardt, H.8
  • 54
    • 0032935664 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases: Specific messages from ubiquitous messengers
    • Schaeffer, H.J. and Weber, M.J., Mitogen-activated protein kinases: specific messages from ubiquitous messengers. Mol. Cell. Biol. 1999, 19: 2435-2544.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 2435-2544
    • Schaeffer, H.J.1    Weber, M.J.2
  • 55
    • 0344443803 scopus 로고    scopus 로고
    • Malignancy in patients with sickle cell disease
    • Schultz, W.H. and Ware, R.E., Malignancy in patients with sickle cell disease. Am. J. Hematol. 2003, 74: 249-253.
    • (2003) Am. J. Hematol. , vol.74 , pp. 249-253
    • Schultz, W.H.1    Ware, R.E.2
  • 57
    • 0034141523 scopus 로고    scopus 로고
    • Quantitative PCR analysis of HbF inducers in primary human adult erythroid cells
    • Smith, R.D., Li, J., Noguchi, C.T. and Schechter, A.N., Quantitative PCR analysis of HbF inducers in primary human adult erythroid cells. Blood 2000, 95: 863-869.
    • (2000) Blood , vol.95 , pp. 863-869
    • Smith, R.D.1    Li, J.2    Noguchi, C.T.3    Schechter, A.N.4
  • 58
    • 0036714366 scopus 로고    scopus 로고
    • Cell-cycle arrest by PD184352 requires inhibition of extracellular signal-regulated kinases (ERK) 1/2 but not ERK5/BMK1
    • Squires, M.S., Nixon, P.M. and Cook, S.J., Cell-cycle arrest by PD184352 requires inhibition of extracellular signal-regulated kinases (ERK) 1/2 but not ERK5/BMK1. Biochem. J. 2002, 366(Pt 2): 673-680.
    • (2002) Biochem. J. , vol.366 , Issue.2 PART , pp. 673-680
    • Squires, M.S.1    Nixon, P.M.2    Cook, S.J.3
  • 59
    • 3042634240 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitors in cancer therapy
    • Srinivasan, M. and Ganesan, T.S., Tyrosine kinase inhibitors in cancer therapy. Clin. Biochem. 2004, 37: 618-635.
    • (2004) Clin. Biochem. , vol.37 , pp. 618-635
    • Srinivasan, M.1    Ganesan, T.S.2
  • 60
    • 0000831381 scopus 로고    scopus 로고
    • Hemoglobin switching
    • Stamatoyannopoulos, G. and Majerus, P.W., Permutter, R.M. and Varmus, H., (eds.), Saunders, Philadelphia
    • Stamatoyannopoulos, G. and Grosveld, F., Hemoglobin switching. In: The Molecular Basis of Blood Diseases, Stamatoyannopoulos, G. and Majerus, P.W., Permutter, R.M. and Varmus, H., (eds.), Saunders, Philadelphia, 2001, pp. 135-185.
    • (2001) The Molecular Basis of Blood Diseases , pp. 135-185
    • Stamatoyannopoulos, G.1    Grosveld, F.2
  • 61
    • 0032529283 scopus 로고    scopus 로고
    • Synergistic activation of MAP kinase (ERK1/2) by erythropoietin and stem cell factor is essential for expanded erythropoiesis
    • Sui, X., Krantz, S.B., You, M. and Zhao, Z., Synergistic activation of MAP kinase (ERK1/2) by erythropoietin and stem cell factor is essential for expanded erythropoiesis. Blood 1998, 92: 1142-1149.
    • (1998) Blood , vol.92 , pp. 1142-1149
    • Sui, X.1    Krantz, S.B.2    You, M.3    Zhao, Z.4
  • 62
    • 0033890345 scopus 로고    scopus 로고
    • Stem cell factor and erythropoietin inhibit apoptosis of human erythroid progenitor cells through different signaling pathways
    • Sui, X., Krantz, S.B. and Zhao, Z.J., Stem cell factor and erythropoietin inhibit apoptosis of human erythroid progenitor cells through different signaling pathways. Br. J. Haematol. 2000, 110:63-70.
    • (2000) Br. J. Haematol. , vol.110 , pp. 63-70
    • Sui, X.1    Krantz, S.B.2    Zhao, Z.J.3
  • 64
    • 3042799365 scopus 로고    scopus 로고
    • Activation of the MAP kinase pathway by c-Kit is PI-3 kinase dependent in hematopoietic progenitor/stem cell lines
    • Wandzioch, E., Edling, C.E., Palmer, R.H., Carlsson, L. and Hallberg, B., Activation of the MAP kinase pathway by c-Kit is PI-3 kinase dependent in hematopoietic progenitor/stem cell lines. Blood 2004, 104: 51-57.
    • (2004) Blood , vol.104 , pp. 51-57
    • Wandzioch, E.1    Edling, C.E.2    Palmer, R.H.3    Carlsson, L.4    Hallberg, B.5
  • 65
    • 0031000626 scopus 로고    scopus 로고
    • Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase
    • Whalen, A.M., Galasinski, S.C., Shapiro, P.S., Nahreini, T.S. and Ahn, N.G., Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase. Mol. Cell. Biol. 1997, 17: 1947-1958.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1947-1958
    • Whalen, A.M.1    Galasinski, S.C.2    Shapiro, P.S.3    Nahreini, T.S.4    Ahn, N.G.5
  • 66
    • 0037901025 scopus 로고    scopus 로고
    • Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK- and MSK1-dependent pathway
    • Wierenga, A.T.J., Vogelzang, I., Eggen, B.J. and Vallenga, E., Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK- and MSK1-dependent pathway. Exp. Hematol. 2003, 31: 398-405.
    • (2003) Exp. Hematol. , vol.31 , pp. 398-405
    • Wierenga, A.T.J.1    Vogelzang, I.2    Eggen, B.J.3    Vallenga, E.4
  • 67
    • 0036735276 scopus 로고    scopus 로고
    • Induction of fetal hemoglobin synthesis by valproate: Modulation of MAP kinase pathways
    • Witt, O., Monkemeyer, S., Kanbach, K. and Pekrun, A., Induction of fetal hemoglobin synthesis by valproate: modulation of MAP kinase pathways. Am. J. Hematol. 2002, 71: 45-46.
    • (2002) Am. J. Hematol. , vol.71 , pp. 45-46
    • Witt, O.1    Monkemeyer, S.2    Kanbach, K.3    Pekrun, A.4
  • 68
    • 0034176006 scopus 로고    scopus 로고
    • Butyrate-induced erythroid differentiation of human K562 leukemia cells involves inhibition of ERK and activation of p38 MAP kinase pathways
    • Witt, O., Sand, K. and Pekrun, A., Butyrate-induced erythroid differentiation of human K562 leukemia cells involves inhibition of ERK and activation of p38 MAP kinase pathways. Blood 2000, 95: 2391-2396.
    • (2000) Blood , vol.95 , pp. 2391-2396
    • Witt, O.1    Sand, K.2    Pekrun, A.3
  • 69
    • 0035298060 scopus 로고    scopus 로고
    • Role of ERK activation in growth and erythroid differentiation of K562 cells
    • Woessmann, W. and Mivechi, N.F., Role of ERK activation in growth and erythroid differentiation of K562 cells. Exp. Cell Res. 2001, 264: 193-200.
    • (2001) Exp. Cell Res. , vol.264 , pp. 193-200
    • Woessmann, W.1    Mivechi, N.F.2
  • 70
    • 2942511897 scopus 로고    scopus 로고
    • ERK signaling pathway is differentially involved in erythroid differentiation of K562 cells depending on time and the inducing agent
    • Woessmann, W., Zwanzger, D. and Borkhardt, A., ERK signaling pathway is differentially involved in erythroid differentiation of K562 cells depending on time and the inducing agent. Cell Biol. Int. 2004, 28: 403-410.
    • (2004) Cell Biol. Int. , vol.28 , pp. 403-410
    • Woessmann, W.1    Zwanzger, D.2    Borkhardt, A.3
  • 71
    • 0033574707 scopus 로고    scopus 로고
    • Modulation of Ras/Raf/extracellular signal-regulated kinase pathway by reactive oxygen species is involved in cyclic strain-induced early growth response-1 gene expression in endothelial cells
    • Wung, B.S., Cheng, J.J., Chao, Y.J., Hsieh, H.J. and Wang, D.L., Modulation of Ras/Raf/extracellular signal-regulated kinase pathway by reactive oxygen species is involved in cyclic strain-induced early growth response-1 gene expression in endothelial cells. Circ. Res. 1999, 84: 804-812.
    • (1999) Circ. Res. , vol.84 , pp. 804-812
    • Wung, B.S.1    Cheng, J.J.2    Chao, Y.J.3    Hsieh, H.J.4    Wang, D.L.5
  • 72
    • 0034114811 scopus 로고    scopus 로고
    • Increased globin production by antisense globin RNA transcripts
    • Xu, L., Ferry, A.E., Monteiro, C. and Pace, B.S., Increased globin production by antisense globin RNA transcripts. Gene Ther. 2000, 7: 438-444.
    • (2000) Gene Ther. , vol.7 , pp. 438-444
    • Xu, L.1    Ferry, A.E.2    Monteiro, C.3    Pace, B.S.4
  • 73
    • 0032005979 scopus 로고    scopus 로고
    • Differentiation inducers modulate cytokine signaling pathways in a murine erythroleukemia cell line
    • Yamashita, T., Wakao, H., Miyajima, A. and Asano, S., Differentiation inducers modulate cytokine signaling pathways in a murine erythroleukemia cell line. Cancer Res. 1998, 58: 556-561.
    • (1998) Cancer Res. , vol.58 , pp. 556-561
    • Yamashita, T.1    Wakao, H.2    Miyajima, A.3    Asano, S.4
  • 74
    • 0035854763 scopus 로고    scopus 로고
    • Sodium butyrate induces transcription from the Gα(i2) gene promoter through multiple Sp1 sites in the promoter and by activating the MEK-ERK signal transduction pathway
    • Yang, J., Kawai, Y., Hanson, R.W. and Arinze, I.J., Sodium butyrate induces transcription from the Gα(i2) gene promoter through multiple Sp1 sites in the promoter and by activating the MEK-ERK signal transduction pathway. J. Biol. Chem. 2001, 276: 25742-25752.
    • (2001) J. Biol. Chem. , vol.276 , pp. 25742-25752
    • Yang, J.1    Kawai, Y.2    Hanson, R.W.3    Arinze, I.J.4
  • 75
    • 0037205479 scopus 로고    scopus 로고
    • ERK negatively regulates the epidermal growth factor-mediated interaction of Gabi and the phosphatidylinositol 3-kinase
    • Yu, C.F., Liu, Z.X. and Cantley, L.G., ERK negatively regulates the epidermal growth factor-mediated interaction of Gabi and the phosphatidylinositol 3-kinase. J. Biol. Chem. 2002, 277: 19382-19388.
    • (2002) J. Biol. Chem. , vol.277 , pp. 19382-19388
    • Yu, C.F.1    Liu, Z.X.2    Cantley, L.G.3
  • 77
    • 4444272661 scopus 로고    scopus 로고
    • Constitutive activation of the MEK/ERK pathway mediates all effects of oncogenic H-ras expression in primary erythroid progenitors
    • Zhang, J. and Lodish, H.F., Constitutive activation of the MEK/ERK pathway mediates all effects of oncogenic H-ras expression in primary erythroid progenitors. Blood 2004, 104: 1679-1687.
    • (2004) Blood , vol.104 , pp. 1679-1687
    • Zhang, J.1    Lodish, H.F.2
  • 78
    • 0027424367 scopus 로고
    • Properties of MEKs, the kinases that phosphorylate and activate the extracellular signal-regulated kinases
    • Zheng, C.F. and Guan, K.-L., Properties of MEKs, the kinases that phosphorylate and activate the extracellular signal-regulated kinases. J. Biol. Chem. 1993, 268: 11435-11439.
    • (1993) J. Biol. Chem. , vol.268 , pp. 11435-11439
    • Zheng, C.F.1    Guan, K.-L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.