N-RAS and K-RAS gene mutations in Brazilian patients with multiple myeloma

Leukemia and Lymphoma

Volumn 47, Issue 2, 2006, Pages 285-289

  Ortega, Manoela M ^a   Faria, Rosa M D ^b   Shitara, Edson S ^a   Assis, Angela M ^a   Albuquerque, Dulcinéia M ^a   Oliveira, José S R ^b   Noguti, Maria A E ^b   Faria, José R ^b   Costa, Fernando F ^a   Lima, Carmen S P ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

K RAS; Multiple myeloma; Mutation; N RAS

Indexed keywords

GENOMIC DNA; K RAS PROTEIN; ONCOPROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BONE MARROW BIOPSY; BRAZIL; CODON; CONTROLLED STUDY; DNA SEQUENCE; EXON; FEMALE; GENE AMPLIFICATION; GENE MUTATION; HETEROZYGOSITY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; MULTIPLE MYELOMA; ONCOGENE K RAS; ONCOGENE N RAS; POLYMERASE CHAIN REACTION; PREVALENCE; PRIORITY JOURNAL; PROTEIN N RAS;

ADULT; AGED; AGED, 80 AND OVER; BRAZIL; EXONS; FEMALE; GENES, RAS; HUMANS; MALE; MIDDLE AGED; MULTIPLE MYELOMA; POINT MUTATION; POLYMERASE CHAIN REACTION; PREVALENCE;

EID: 30644465656     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.1080/10428190500300969     Document Type: Article

References (25)

1. Neri, A and Murphy, J and Cro, P and Ferrero, D and Tarella, C and Baldini, L and (1989) Ras oncogene mutation in multiple myeloma J Exp Med, 170, pp. 1715 - 1725.
2. Paquette, R and Berenson, J and Lichtenstein, A and McCormick, F and Koeffler, H. (1990) Oncogenes in multiple myeloma: Point mutation of N-ras Oncogene, 5, pp. 1659 - 1663.
3. Matozaki, S and Nakagawa, T and Nakao, Y and Fujita, T. (1991) RAS gene mutations in multiple myeloma and related monoclonal gammopathies Kobe J Med Sci, 37, pp. 35 - 45.
4. Portier, M and Moles, J and Mazars, G and Jeanteur, P and Bataille, R and Klein, B and (1992) P53 and RAS gene mutations in multiple myeloma Oncogene, 7, pp. 2539 - 2545.
5. Liu, P and Leong, T and Quam, L and Billadeau, D and Kay, N and Greip, P and (1996) Activating mutations of N- and K-ras in multiple myeloma show different clinical associations: Analysis of the Eastern Cooperative Oncology Group phase III trail Blood, 88, pp. 2699 - 2706.
6. Hallek, M and Lelf, P and Anderson, K. (1998) Multiple myeloma: increasing evidence for a multistep transformation process Blood, 91, pp. 3 - 21.
7. Tanaka, K and Takechi, M and Asaoku, H and Dohy, H and Kamada, N. (1992) A high frequency of N-RAS oncogene mutations in multiple myeloma Int J Hematol, 56, pp. 119 - 127.
8. Berenson, J and Bergsagel, P and Munshi, N. (1999) Initiation and maintenance of multiple myeloma Semin Hematol, 36, pp. 9 - 13.
9. Bezieau, S and Devilder, M and Avet-Loiseau, H and Mellerin, M and Puthier, D and Pennarun, E and (2001) High incidence of N and K-Ras activating mutations in multiple myeloma and primary plasma cell leukaemia at diagnosis Hum Mutat, 18, pp. 212 - 224.
10. Kalakonda, N and Rothwell, D and Scarffe, H and Norton, J. (2001) Detection of N-Ras codon 61 mutations in subpopulations of tumor cells in multiple myeloma Blood, 98, pp. 1555 - 1560.
11. Rasmussen, T and Kuehl, M and Lodahl, M and Johnsen, H and Dahl, I. (2005) Possible roles for activating RAS mutations in the MGUS to MM transition and in the intramedullary to extramedullary transition in some plasma cell tumors Blood, 105, pp. 317 - 323.
12. Billadeau, D and Jelinek, D and Shan, N and LeBien, T and Van Ness, B. (1995) Introduction of an activated N-ras oncogene alters the growth characteristics of the interleukin 6-dependent myeloma cell line ANBL6 Cancer Res, 55, pp. 3640 - 3646.
13. Duncan, B and Schmidt, M and Polansky, C. (1992) High mortality rates among Brazilian adult populations - an international comparison Revista da Associação Médica Brasileira, 38, pp. 138 - 144.
14. Barlogie, B and Shaughnessy, J and Munshi, N and Epstein, J.(2001) Plasma cell myeloma. In Hematology. (pp. 1279 - 1304). New York NY: McGraw-Hill.
15. Durie, B and Salmon, S. (1975) A clinical staging system for multiple myeloma Cancer, 36, pp. 842 - 854.
16. Saiki, R and Gelfand, D and Stoffel, S and Scharf, S and Higuchi, R and Horn, G and (1988) Primer-directed enzymatic amplification of DNA with thermostable DNA polymerase Science, 239, pp. 487 - 491.
17. Ahuja, H and Forti, A and Bar-Eli, M and Cline, M. (1990) The pattern of mutational involvement of ras genes in human hematologic malignancies determined by DNA amplification and direct sequencing Blood, 75, pp. 1684 - 1690.
18. Corradini, P and Ladetto, M and Voena, C and Palumbo, A and Inghirami, G and Knowles, D and (1993) Mutational activation of N- and K-ras oncogenes in plasma cell dyscrasia Blood, 81, pp. 2708 - 2713.
19. Yasuga, Y and Hirosawa, S and Yamamoto, K and Tomiyama, J and Nagata, K and Aoki, N. (1995) N-ras and p53 gene mutations are very rare events in multiple myeloma Int J Hematol, 62, pp. 91 - 97.
20. Byrne, J and Marshall, C. (1998) The molecular pathophysiology of myeloid leukaemias: Ras revisited Br J Haematol, 100, pp. 256 - 264.
21. Barbacid, M. (1987) Ras gene Ann Rev Biochem, 56, pp. 779 - 827.
22. Radich, J and Kopecky, K and Willman, C and Weick, J and Head, D and Appelbaum, F and (1990) N-ras mutations in adult de novo acute myelogenous leukaemia: Prevalence and clinical significance Blood, 76, pp. 801 - 807.
23. Ballerini, P and Gaidano, G and Gong, J and Tassi, V and Saglio, G and Knowles, D and (1993) Multiple genetic lesions in acquired immunodeficiency syndrome-related non-Hodgkin's lymphoma Blood, 81, pp. 166 - 176.
24. Brose, M and Volpe, P and Feldman, M and Kumar, M and Rishi, I and Gerrero, R and (2002) BRAF and RAS mutations in human lung cancer and melanoma Cancer Res, 62, pp. 6997 - 7000.
25. Yuen, S and Davies, H and Chan, T and Ho, J and Bignell, G and Cox, C and (2002) Similarity of the phenotypic patterns associated with BRAF and KRAS mutations in colorectal neoplasia Cancer Res, 62, pp. 6451 - 6455.