High-dose lidocaine reduces airway mucus transport velocity in intubated anesthetized dogs

Respiratory Medicine

Volumn 100, Issue 2, 2006, Pages 258-263

  Gosselink, Rik ^a   Gayan Ramirez, Ghislaine ^a   Houtmeyers, Els ^a   de Paepe, Kristel ^a   Decramer, Marc ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Dogs; Lidocaine; Local anesthesia; Mucociliary transport; Mucus transport; Viscoelasticity

Indexed keywords

ACTIVATED CARBON; LIDOCAINE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ARTICLE; BRONCHOSCOPY; BRONCHUS MUCUS; CLINICAL ASSESSMENT; CONTROLLED STUDY; COUGHING; DOG; DOSE RESPONSE; DRUG INSTILLATION; DRUG MEGADOSE; ENDOTRACHEAL INTUBATION; FLOW RATE; LOCAL ANESTHESIA; LOW DRUG DOSE; MUCOCILIARY CLEARANCE; MUCUS TRANSPORT VELOCITY; NONHUMAN; PRIORITY JOURNAL; TRACHEA MUCUS; VISCOELASTICITY;

ANESTHETICS, LOCAL; ANIMALS; BRONCHI; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELASTICITY; INTUBATION, INTRATRACHEAL; LIDOCAINE; MUCUS; VISCOSITY;

EID: 30544453338     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rmed.2005.04.028     Document Type: Article

References (30)

1. M.A. Sackner M.J. Rosen A. Wanner Estimation of tracheal mucous velocity by bronchofiberscopy J Appl Physiol 34 1973 495-499
2. M. King D.M. Phillips D. Gross V. Vartian H.K. Chang A. Zidulka Enhanced tracheal mucus clearance with high frequency chest wall compression Am Rev Respir Dis 128 1983 511-515
3. F. Konrad S. Schraag T. Marx J. Kilian A. Goertz The effect of total intravenous anesthesia with propofol, alfentanil and vecuronium (TIVA) on bronchial mucosal transport Anasthesiol Intensivmed Notfallmed Schmerzther 33 1998 171-176
4. F. Konrad T. Marx M. Schraag J. Kilian Combination anesthesia and bronchial tranport velocity. Effects of anesthesia with isoflurane, fentanyl, vecuronium and oxygen-nitrous oxide breathing on bronchial mucus transport Anaesthesist 46 1997 403-407
5. M. Friedman F.D. Stott D.O. Poole R. Dougherty G.A. Chapman H. Watson M.A. Sackner A new roentgenographic method for estimating mucous velocity in airways Am Rev Respir Dis 155 1977 67-72
6. J.F. Landa J.A. Hirsch M.I. Lebeaux Effects of topical and general anesthetic agents on tracheal mucous velocity of sheep J Appl Physiol 38 1975 946-948
7. M. Armengot J. Basterra E. Garcia-Bartual The influence of anesthetics and vasoconstrictors on nasal mucociliary transport Acta Otorhinolaryngol Belg 43 1989 149-156
8. C.M. Rossman M.T. Newhouse Effect of lidocaine on nasal mucociliary clearance in normals and smokers Am Rev Respir Dis 115 suppl 1977 239
9. J. Rutland W. Griffin P. Cole Nasal brushing and measurement of ciliary beat frequency. An in vitro method for evaluating pharmacologic effects on human cilia Chest 80 suppl 1981 865-867
10. J. Rutland W. Griffin P.J. Cole An in vitro model for studying the effects of pharmacological agents on human ciliary beat frequency: effects of lignocaine Br J clin Pharmacol 13 1982 679-683
11. K.J.A.O. Ingels M.R. Nijziel K. Graamans E.H. Huizing Influence of cocaine and lidocaine on human nasal cilia. Beat frequency and harmony in vitro Arch Otolaryngol Head Neck Surg 120 1994 197-201
12. B.R. Manawadu S.R. Mostow F.M. LaForce Local anesthetics and tracheal ring ciliary activity Anesth Analg 57 1978 448-452
13. S.R. Mostow R.B. Dreisin B.R. Manawadu F.M. LaForce Adverse effects of lidocaine and methylparaben on tracheal ciliary activity Laryngoscope 89 1979 1697-1701
14. J.P. Dudley J.D. Cherry Effect of topical anesthetics on ciliary activity of chicken embryo tracheal organ cultures Ann Otol 87 1978 533-537
15. Y. Roth E.F. Aharonson H. Teichtahl G.L. Baum Z. Priel M. Modan Human in vitro nasal and tracheal ciliary beat frequencies: Comparison of sampling sites, combined effect of medication, and demographic relationships Ann Otol Rhinol Laryngol 100 1991 378-384
16. M. Somerville J.-A. Karlsson P.S. Richardson The effects of local anaesthetic agents upon mucus secretion in the feline trachea in vivo Pulm Pharmacol 3 1990 93-101
17. R.J. Phipps P.S. Richardson A. Corfield J.T. Gallagher P.K. Jeffery P.W. Kent M. Passatore A physiological, biochemical and histological study of goose tracheal mucin and its secretion Phil Trans R Soc London 279 1977 513-543
18. M. Somerville P.S. Richardson Local anaesthesia of the trachea and mucus secretion Symp Soc Exp Biol 43 1989 193-199
19. C.G. Phillips S.R. Kaye Diameter-based analysis of the branching geometry of four mammalian bronchial trees Respir Physiol 102 1995 303-316
20. King M, Rubin BK. Rheology of airway mucus: Relationship with clearance function. In: Takishima T, Shimura S, editors. Airway secretion: physiological bases for the control of mucous hypersecretion (lung biology in health and disease: Volume 72), 1st ed. New York: Marcel Dekker, Inc.; 1994. p. 283-314.
21. M. King The role of mucus viscoelasticity in cough clearance Biorheology 24 1987 589-597
22. N.K. Schonemann M. van der Burght L. Arendt-Nielsen P. Bjerring Onset and duration of hypoalgesia of lidocaine spray applied to oral mucosa - a dose response study Acta Anaesthesiol Scand 36 1992 733-735
23. M. Kokubu K. Oda M. Machida M. Shinya New lidocaine ester derivats with prolonged anesthetic effect J Anesth 4 1990 270-274
24. M. King L.A. Engel P.T. Macklem Effect of pentobarbital anesthesia on rheology and transport of canine tracheal mucus J Appl Physiol 46 1979 504-509
25. G.S. Padda C. Kishioka B.K. Rubin Propofol and methohexital have no significant effect on mucus secretion or clearance in the anaesthezed dao Crit Care Med 29 2001 1045-1048
26. S.L. Winters D.B. Yeates Roles of hydration, sodium, and chloride in regulation of canine mucociliary transport system J Appl Physiol 83 1997 1360-1369
27. E. Daviskas S.D. Anderson I. Gonda S. Eberl S. Meikle J.P. Seale G. Bautovich Inhalation of hypertonic saline aerosol enhances mucociliary clearance in asthmatic and healthy subjects Eur Respir J 9 1996 725-732
28. S.L. Winters D.B. Yeate Interaction between ion transporters and the mucociliary transport system in dog and baboon J Appl Physiol 83 1997 1348-1359
29. J. Pickles M. Jeffrey A. Datta A.A. Jeffrey Is preparation for bronchoscopy optimal? Eur Respir J 22 2003 203-206
30. F. Konrad T. Schreiber A. Grunert M. Clausen F.W. Ahnefeld Measurement of mucociliary transport velocity in ventilated patients. Short-term effect of general anesthesia on mucociliary transport Chest 102 1992 1377-1383