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Volumn 15, Issue 11, 2005, Pages 712-715

Impact of metformin therapy in patients with polycystic ovarian syndrome

Author keywords

Anovulation; Hyperinsulinemia; Metformin; Polycystic ovarian syndrome (PCOS); Serum fasting insulin levels

Indexed keywords

FOLIC ACID; GLUCOSE; INSULIN; METFORMIN;

EID: 30544446305     PISSN: 1022386X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (9)

References (17)
  • 2
    • 0034521558 scopus 로고    scopus 로고
    • Induction of ovulation in infertile women with hyperandrogenism and insulin resistance
    • Robert L, Barbieri MD. Induction of ovulation in infertile women with hyperandrogenism and insulin resistance. Am J Obstet Gynaecol 2000; 183: 1412-8.
    • (2000) Am J Obstet Gynaecol , vol.183 , pp. 1412-1418
    • Robert, L.1    Barbieri, M.D.2
  • 3
    • 0142247208 scopus 로고    scopus 로고
    • Metformin in polycystic ovary syndrome: Systematic review and meta-analysis
    • Lord JM, Flight IH, Norman RJ, Metformin in polycystic ovary syndrome: systematic review and meta-analysis. BMJ 2003; 327: 951-3.
    • (2003) BMJ , vol.327 , pp. 951-953
    • Lord, J.M.1    Flight, I.H.2    Norman, R.J.3
  • 4
    • 0344874559 scopus 로고    scopus 로고
    • Obese patients with polycystic ovary syndrome: Evidence that metformin does not restore. Sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by ovarian steroids
    • Eagleson CA, Bellows AB, Kathyhu, Gingrich MB, Marshall JC. Obese patients with polycystic ovary syndrome: evidence that metformin does not restore. sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by ovarian steroids. J Clin Endocrinol Metab 2003, 88: 5158-65.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 5158-5165
    • Eagleson, C.A.1    Bellows, A.B.2    Kathyhu3    Gingrich, M.B.4    Marshall, J.C.5
  • 5
    • 0024381472 scopus 로고
    • Suppression of serum insulin by diazoxide reduce serum testosterone levels in obese women with polycystic ovary syndrome
    • Nestler JE, Bar Lascini CO, Matt DW, Steingold KA, Plymate SR, Clore JN, et al. Suppression of serum insulin by diazoxide reduce serum testosterone levels in obese women with polycystic ovary syndrome. J Clin Endocrinol Metab 1989; 68: 1027-32.
    • (1989) J Clin Endocrinol Metab , vol.68 , pp. 1027-1032
    • Nestler, J.E.1    Bar Lascini, C.O.2    Matt, D.W.3    Steingold, K.A.4    Plymate, S.R.5    Clore, J.N.6
  • 6
    • 0027399661 scopus 로고
    • Effects of metformin on insulin resistance, risk factors for cardiovascular disease and plasminogen activator inhibitor in niddm subjects: A study of two ethnic groups
    • Nagi DK, Yudkn JS, Effects of metformin on insulin resistance, risk factors for cardiovascular disease and plasminogen activator inhibitor in niddm subjects: a study of two ethnic groups. Diabetes Care 1993; 16: 621-9.
    • (1993) Diabetes Care , vol.16 , pp. 621-629
    • Nagi, D.K.1    Yudkn, J.S.2
  • 7
    • 0034458234 scopus 로고    scopus 로고
    • Metformin effects on clinical features, endocrine and metabolic profiles, and insulin sensitivity in polycystic ovary syndrome. A randomized, double blind, placebo-controlled 6 months trial, followed by open long-term clinical evaluation
    • Moghetti P, Castello R, Negri C, Tusi F, Perrone F, Caputo M, et al. Metformin effects on clinical features, endocrine and metabolic profiles, and insulin sensitivity in polycystic ovary syndrome. A randomized, double blind, placebo-controlled 6 months trial, followed by open long-term clinical evaluation. J Clin Endocrinol Metab 2000; 89: 139-46.
    • (2000) J Clin Endocrinol Metab , vol.89 , pp. 139-146
    • Moghetti, P.1    Castello, R.2    Negri, C.3    Tusi, F.4    Perrone, F.5    Caputo, M.6
  • 8
    • 0032565971 scopus 로고    scopus 로고
    • Effects of metformin on spontaneous and clomiphene induced ovulation in the ploycystic ovary syndrome
    • Nestuer JE, Jakubowicz DJ, Evans WS, Pasqual R. Effects of metformin on spontaneous and clomiphene induced ovulation in the ploycystic ovary syndrome. N Engl J Med 1998; 338: 1876-80.
    • (1998) N Engl J Med , vol.338 , pp. 1876-1880
    • Nestuer, J.E.1    Jakubowicz, D.J.2    Evans, W.S.3    Pasqual, R.4
  • 10
    • 0028315971 scopus 로고
    • Metformin therapy in polycystic ovary syndrome reduces hyperinsulinemia, insulin resistance, hyperandrogenemia, and systolic blood pressure, white facilitating normal menses and pregnancy
    • Velazquez EM, Mendoza S, Hamer T, Sosa F, Glueck CJ, Metformin therapy in polycystic ovary syndrome reduces hyperinsulinemia, insulin resistance, hyperandrogenemia, and systolic blood pressure, white facilitating normal menses and pregnancy. Metabolism 1994; 43: 647-54.
    • (1994) Metabolism , vol.43 , pp. 647-654
    • Velazquez, E.M.1    Mendoza, S.2    Hamer, T.3    Sosa, F.4    Glueck, C.J.5
  • 11
    • 0032565971 scopus 로고    scopus 로고
    • Effects of metformin on spontaneous and clomiphene induced ovulation in the polycystic ovary syndrome
    • Nestler JE, Jakubowicz DJ, Evans WS, Pasquali R. Effects of metformin on spontaneous and clomiphene induced ovulation in the polycystic ovary syndrome. N Engl J Med 1998, 338: 1876-80.
    • (1998) N Engl J Med , vol.338 , pp. 1876-1880
    • Nestler, J.E.1    Jakubowicz, D.J.2    Evans, W.S.3    Pasquali, R.4
  • 12
    • 0030783316 scopus 로고    scopus 로고
    • Lean women with polycystic ovary syndrome respond to insulin reduction with decreases in ovarian p 450c 17 and activity and serum androgens
    • Nestler JE, Jakubowicz DJ. Lean women with polycystic ovary syndrome respond to insulin reduction with decreases in ovarian p 450c 17 and activity and serum androgens. J Clin Endocrinol Metab 1997; 82: 4075.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 4075
    • Nestler, J.E.1    Jakubowicz, D.J.2
  • 13
    • 0035044332 scopus 로고    scopus 로고
    • Insulin reduction with metformin increases luteal phase serum glycodein and insulin - Like growth factor-binding protein 1 concentrations and enhances uterine vascularity and blood flow in the polycystic ovary syndrome
    • Jakubowicz DJ, Seppala M, Jakubowicz S, Rodriguez - Armas O, Rivas-Santiago A, Koistinen H, et al. Insulin reduction with metformin increases luteal phase serum glycodein and insulin - like growth factor-binding protein 1 concentrations and enhances uterine vascularity and blood flow in the polycystic ovary syndrome. J Clin Endocrinol Metab 2001: 86: 1126-33.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1126-1133
    • Jakubowicz, D.J.1    Seppala, M.2    Jakubowicz, S.3    Rodriguez-Armas, O.4    Rivas-Santiago, A.5    Koistinen, H.6
  • 14
    • 0036177496 scopus 로고    scopus 로고
    • CO - Administration of metformin during rFSH treatment in patients with clomiphene citrate-resistant polycystic ovarian syndrome: A prospective randomized trial
    • Yarali H, Yildiz BO, Demirol A, Zeyneloglu HB, Yigit N, Bukulmez O, et al. CO -administration of metformin during rFSH treatment in patients with clomiphene citrate-resistant polycystic ovarian syndrome: a prospective randomized trial: Hum Reprod 2002; 17: 289-94.
    • (2002) Hum Reprod , vol.17 , pp. 289-294
    • Yarali, H.1    Yildiz, B.O.2    Demirol, A.3    Zeyneloglu, H.B.4    Yigit, N.5    Bukulmez, O.6
  • 15
    • 0028315971 scopus 로고
    • Metformin therapy in polycystic ovary syndrome reduces hyperinsulinemia, insulin resistance, hyperandrogenemia and systolic blood pressure, while facilitating normal menses and pregnancy
    • Velazquez EM, Mendoza S, Hamer T, Sosa F, Glueck CJ. Metformin therapy in polycystic ovary syndrome reduces hyperinsulinemia, insulin resistance, hyperandrogenemia and systolic blood pressure, while facilitating normal menses and pregnancy. Metabolism 1994; 43: 647-54.
    • (1994) Metabolism , vol.43 , pp. 647-654
    • Velazquez, E.M.1    Mendoza, S.2    Hamer, T.3    Sosa, F.4    Glueck, C.J.5
  • 16
    • 0036283875 scopus 로고    scopus 로고
    • Metformin therapy in obese adolescents with polycystic ovary syndrome and impaired glucose tolerance
    • Arslanian SA, Lewy V, Danadian K, Rola Saad R. Metformin therapy in obese adolescents with polycystic ovary syndrome and impaired glucose tolerance. J Clin Endocrinol Metabol 2002; 87: 1555-9.
    • (2002) J Clin Endocrinol Metabol , vol.87 , pp. 1555-1559
    • Arslanian, S.A.1    Lewy, V.2    Danadian, K.3    Rola Saad, R.4
  • 17
    • 0031787388 scopus 로고    scopus 로고
    • A fasting glucose to insulin ratio is a useful measure of insulin sensivity in women with polycystic ovary syndrome
    • Legrors, Fine Good D, Dunaif A. A fasting glucose to insulin ratio is a useful measure of insulin sensivity in women with polycystic ovary syndrome. J Clin Endocrinol Metab 1998; 83: 2694-8.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 2694-2698
    • Legrors1    Fine Good, D.2    Dunaif, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.