The BeLPT: Algorithms and implications

American Journal of Industrial Medicine

Volumn 49, Issue 1, 2006, Pages 36-44

  Middleton, D C ^a   Lewin, M D ^a   Kowalski, P J ^a   Cox, S S ^a   Kleinbaum, D ^b  

^a AGENCY FOR TOXIC SUBSTANCES AND DISEASE REGISTRY   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

Beryllium; Chronic beryllium disease; Lymphocyte; Proliferation; Pulmonary disease; Screening; Sensitivity; Specificity

Indexed keywords

BERYLLIUM;

ALGORITHM; ARTICLE; BERYLLIOSIS; BERYLLIUM LYMPHOCYTE PROLIFERATION TEST; COMPARATIVE STUDY; CONTACT SENSITIZATION; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST; DIAGNOSTIC VALUE; EPIDEMIOLOGICAL DATA; HUMAN; IMMUNOPATHOLOGY; LYMPHOCYTE PROLIFERATION; MEDICAL DECISION MAKING; PERFORMANCE; STANDARDIZATION; VALIDATION PROCESS;

ALGORITHMS; BERYLLIOSIS; BERYLLIUM; CELL PROLIFERATION; FALSE POSITIVE REACTIONS; HUMANS; IMMUNOLOGIC TESTS; LYMPHOCYTE ACTIVATION; MODELS, STATISTICAL; PREDICTIVE VALUE OF TESTS; T-LYMPHOCYTES;

EID: 30544432094     PISSN: 02713586     EISSN: 10970274     Source Type: Journal    
DOI: 10.1002/ajim.20241     Document Type: Article

References (27)

1. Deubner DC, Goodman M, Iannuzzi J. 2001. Variability, predictive value, and uses of the beryllium blood lymphocyte proliferation test (BLPT): Preliminary analysis of the ongoing workforce survey. Appl Occup Environ Hyg 16:521-526.
2. Eisenbud M. 1982. Origins of the standards for control of beryllium disease (1947-1949). Environ Res 27:79-88.
3. Eisenbud M, Lisson J. 1983. Epidemiological aspects of beryllium-induced nonmalignant lung disease. J Occup Med 25:196-202.
4. Fireman E, Haimsky E, Noiderfer M, Priel I, Lerman Y. 2003. Misdiagnosis of sarcoidosis in patients with chronic beryllium disease. Sarcoidosis Vasc Diffuse Lung Dis 20:144-148.
5. Fleiss JL. 1981. Statistical methods for rates and proportions. 2nd ed. New York: John Wiley & Sons.
6. Fleiss JL, Levin B, Paik MC. 2003. Statistical methods for rates and proportions. 3rd ed. New York: John Wiley & Sons.
7. Fontenot AP, Falta MT, Freed BM, Newman LS, Kotzin BL. 1999. Identification of pathogenic T Cells in patients with beryllium-induced lung disease. J Immunol 163:1019-1026.
8. Henneberger PK, Goe SK, Miller WE, Doney B, Groce DW. 2004. Industries in the United States with airborne beryllium exposure and estimates of the number of current workers potentially exposed. J Occup Env Hyg 1:648-659.
9. Hennekens CH, Buring JE. 1987. Epidemiology in medicine. Boston: Little Brown and Company.
10. Kreiss K, Newman LS, Mroz MN, Campbell PA. 1989. Screening blood test identifies subclinical beryllium cases. J Occup Med 31:603-608.
11. Kreiss K, Mroz MM, Zhen B, Wiederman H, Barna B. 1997. Risks of beryllium disease related to work processes at a metal, alloy, and oxide production plant. J Occup Environ Med 54(8):605-612.
12. Maier LA. 2002. Clinical approach to chronic beryllium disease and other nonpneumoconiotic interstitial lung diseases. Journal of Thoracic Imaging 17(4):273-284.
13. Middleton DC. 1998. Chronic beryllium disease: Uncommon disease, less common diagnosis. Environ Health Perspect 106:765-767.
14. National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention. 2003. Beryllium research highlights. Available at http://www.cdc.gov/niosh/topics/beryllium/newsletter. html. Accessed 8 August 2005.
15. Newman LS. 1996. Significance of the blood beryllium lymphocyte proliferation test. Environ Health Perspect 104(suppl 5):953-956.
16. Newman LS. 2000. Immunologic mechanisms in granulomatous lung disease. Immunopharmacology 48:329-331.
17. Newman LS, Kreiss K, King TE Jr., Seay S, Campbell PA. 1989. Pathologic and immunologic alterations in early stages of beryllium disease, Re-examination of disease definition and natural history. Am Rev Respir Dis 139:1479-1486.
18. Newman LS, Lloyd J, Daniloff E. 1996. The natural history of beryllium sensitization and chronic beryllium disease. Environ Health Perspect 104(suppl 5):937-943.
19. Newman LS, Maier LA, Martyny JW, Mroz MM, Van Dyke M, Sackett HM. 2005. Beryllium workers' health risks [letter]. J Occup Environ Hyg June 2:D48-D50.
20. Stange AW, Furman FJ, Hilmas DE. 2004. The beryllium lymphocyte proliferation test: Relevant issues in beryllium health surveillance. Am J Ind Med 46:453-462.
21. Sterner JH, Eisenbud M. 1951. Epidemiology of beryllium intoxication. Ind Hyg Occup Med 4:123-151.
22. U.S. Department of Energy. 1999. Chronic Beryllium Disease Prevention Program; Final Rule. 10 CFR 850.
23. U.S. Department of Labor. 2002. Occupational exposure to beryllium: Request for information. Federal Register 67:70707-70712.
24. U.S. Department of the Air Force. 2002. Beryllium surveillance and medical monitoring policy [memorandum of 28 August 2002].
25. U.S. Department of the Army. 2002a. Work place exposure to beryllium [memorandum of 7 May, AMCSG-I, 40-5e].
26. U.S. Department of the Army. 2002b. Beryllium surveillance and medical monitoring policy [memorandum of 15 August, DASG-PPMNC].
27. Welch L, Ringen K, Bingham E, Dement J, Takaro T, McGowan W, Chen A, Quinn P. 2004. Screening for beryllium disease among construction trade workers at Department of Energy nuclear sites. Am J Ind Med 46:207-218.