Efficient high performance liquid chromatograph/ultraviolet method for determination of diclofenac and 4′-hydroxydiclofenac in rat serum

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 830, Issue 2, 2006, Pages 231-237

  Kaphalia, Lata ^a   Kaphalia, Bhupendra S ^a   Kumar, Santosh ^a   Kanz, Mary F ^a   Treinen Moslen, Mary ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

4 Hydroxydiclofenac; Cytochrome P450 3A4; Diclofenac; Metabolism

Indexed keywords

BLOOD; LIVING SYSTEMS STUDIES; METABOLISM; METABOLITES; ULTRAVIOLET RADIATION;

4-HYDROXYDICLOFENAC; CYTOCHROME P450 3A4; DICLOFENAC;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

4' HYDROXYDICLOFENAC; 5 HYDROXYDICLOFENAC; CYTOCHROME P450 3A4; DICLOFENAC; DRUG METABOLITE; EFENAMIC ACID; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG SELECTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SENSITIVITY ANALYSIS; SERUM; ULTRAVIOLET RADIATION;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DICLOFENAC; MALE; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SPECTROPHOTOMETRY, ULTRAVIOLET;

ANIMALIA;

EID: 30444449007     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2005.10.045     Document Type: Article

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