Synthesis and antitumor activity of cannabigerol

Archives of Pharmacal Research

Volumn 19, Issue 3, 1996, Pages 228-230

  Baek, Seung Hwa ^c   Han, Du Seok ^a   Yook, Chan Nam ^b   Kim, Young Chae ^c   Kwak, Jung Suk ^c  

^a Wonkwang University   (South Korea)

^b Wonkwang Health College   (South Korea)

^c NONE

Author keywords

Antitumor activity; Cannabigerol; Mouse skin melanoma cell

Indexed keywords

EID: 3042949364     PISSN: 02536269     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02976895     Document Type: Article

References (13)

1. Baek, S. H., Yook, C. N., and Han, D. S.: Boron trifluoride etherate on alumina-A modified Lewis acid reagent(V). A convenient single step synthesis of cannabinoids. Bull. Kor. Chem. Soc. 16(3), 293-296 (1991).
2. Baek, S. H., Srebnik, M., and Mechoulam, R.: Boron trifluoride etherate on alumina-A modified Lewis acid reagent. An improved synthesis of cannabidiol. Tetrahedron Lett. 26(8), 1083-1086 (1985).
3. Baik, K. U., and Ahn, B. Z.: Cyctotoxic activities of some geranylated flavones against L 1210 cell. J. Pharm. Soc. Korea, 32(2), 125-128 (1988).
4. Colasanti, B. K., and Gong, H. Marihuana 87, Chesher, G.; Consroe, P.; Musty, R. Ed., Australian Government Publishing Service, Canberra, pp.119-124 (1988).
5. Carmichael, J., Degraff, W. G., Gazdar, A. F., Minna, J. D., and Mitchell, J. B.: Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing. Cancer Res. 47, 936-942 (1987).
6. Dewey, W. L.: Cannabinoid pharmacology. Pharmacol. Rev. 38, 151-178 (1986).
7. Kleinman, S., Weitzman, S. A., Cassem, N., and Andrews, E.: Double blind trial of δ-9-tetrahydrocannabinol (THC) as an adjunct to prochlorperazine for chemotherapy-induced vomiting. Curr. Ther. Res. 34, 1014-1017 (1983).
8. Kang, K. S., Ryu, S. H., and Ahn, B. Z.: Antineoplastic natural products and the analogues VI. Arch. Pharm. Res. 8, 187-190 (1985).
9. Mechoulam, R.: In Cannabinoid as therapeutic agents, Boca Raton, CRC Press Inc., (1986).
10. Mosmann, T. J.: Rapid colorimetric assays for cellular growth and survival : application to proliferation and cytotoxicity assays. Immunol. Methods, 65, 55-63 (1983).
11. McCabe, M., Smith, F. P., Macdonald, J. S., and Woolley, P. V.: Efficacy of tetrahydrocannabinol in patients refractory to standard antiemetic therapy. Invest. New Drugs. 6, 243-246 (1988).
12. Plasse, T. F., Gorter, R. W., Krasnow, S. H., Lane, M., Shepard, K. V., and Wadleig H, R. G.: Recent clinical experince with dronabinol. Pharmacol. Biochem. Behav. 40, 695-700 (1991).
13. Sallan, S. E., Cronin, C., Zelen, M., and Zinberg, N. E.: Antiemetics in patients receiving chemotherapy for cancer: A randomized comparison of δ-9-tetrahydrocannabinol and prochlorperazine. N. Engl. J. Med. 302, 135-138 (1980)