HIV topical microbicides: Steer the ship or run aground

American Journal of Public Health

Volumn 94, Issue 7, 2004, Pages 1085-1089

  Gross, Michael ^a  

^a NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTIVIRUS AGENT; CELLULOSE SULFATE; DEXTRIN; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; POLYANION; SURFACTANT;

HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION CONTROL; MOLECULAR MECHANICS; PH; REVIEW; SAFETY; SAMPLE SIZE; TARGET CELL; TREATMENT OUTCOME; VIRUS ADSORPTION;

EID: 3042857780     PISSN: 00900036     EISSN: None     Source Type: Journal    
DOI: 10.2105/AJPH.94.7.1085     Document Type: Review

References (9)

1. Office of AIDS Research, National Institutes of Health, US Dept of Health and Human Services. FY2005 budget. Available at: http://www.nih.gov/od/oar/ public/pubs/fy2005/2005cj.pdf. Accessed March 5, 2004.
2. Lite J. New push on for woman-controlled prevention. Available at: http://www.womensenews.org/article.cfm?aid=913. Accessed March 5, 2004.
3. VanDamme L, Ramjee G, Alary M, et al. Effectiveness of COL-1492, a nonxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: a randomized controlled trial. Lancet. 2002; 360:971-977.
4. Krebs FC, Miller SR, Catalone BJ, et al. Sodium dodecyl sulfate and C31G as microbicidal alternatives to nonoxynol 9: comparative sensitivity of primary human vaginal keratinocytes. Antimicrob Agents Chemother. 2000;44: 1954-1960.
5. Bax R, Douville K, McCormick D, et al. Microbicides-Evaluating multiple formulations of C31G. Contraception. 2002;66:365-368.
6. Hoosen A, Coetzee N, Blanchard K, et al. A randomized, placebo-controlled double-blind expanded safety trial of Carraguard™ microbicide gel in South Africa: RTI/STI at baseline and follow-up. In: Programs and abstracts of the Microbicides 2002 conference, May 2002, Antwerp, Belgium. Abstract B-071.
7. Neurath A, Strick N, Li Y-Y. Anti-HIV-1 activity of anionic polymers: a comparative study of candidate microbicides. BMC Infect Dis [serial online]. 2002;2:27-38. Available at: http://www.biomedcentral.com/1471-2334/2/27. Accessed March 5, 2004.
8. Otten RA, Adams DR, Kim CN, et al. Cellulose acetate phthalate protects macaques from multiple low-dose vaginal exposures with an SHIV virus: new strategy to study HIV preclinical interventions in non-human primates. In: Program and abstracts of the XI Conference on Retroviruses and Opportunistic Infections, February 2004, San Francisco, Calif. Paper 159.
9. Shattock R. How close are we to an effective microbicide? In: Program and abstracts of the XI Conference on Retroviruses and Opportunistic Infections, February 2004, San Francisco, Calif.