Spectroscopic and computational studies on the adenosylcobalamin-dependent methylmalonyl-CoA mutase: Evaluation of enzymatic contributions to Co-C bond activation in the Co3+ ground state

Journal of the American Chemical Society

Volumn 126, Issue 26, 2004, Pages 8167-8180

  Brooks, Amanda J ^a   Vlasie, Monica ^b   Banerjee, Ruma ^b   Brunold, Thomas C ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; GROUND STATE; PERTURBATION TECHNIQUES; PROBABILITY DENSITY FUNCTION; SUBSTRATES;

COFACTORS; MAGNETIC CIRCULAR DICHROISM (MCD);

ENZYMES;

BENZIMIDAZOLE DERIVATIVE; CARBON; COBALT; COBAMAMIDE; HISTIDINE; HOLOENZYME; MECOBALAMIN; METHYLMALONYL COENZYME A MUTASE;

ABSORPTION SPECTROSCOPY; ARTICLE; CALCULATION; CHEMICAL BOND; CIRCULAR DICHROISM; DENSITY FUNCTIONAL THEORY; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; EVALUATION; MOLECULAR STABILITY; SPECTROSCOPY; STEREOSPECIFICITY;

BINDING SITES; CIRCULAR DICHROISM; COBALT; COBAMIDES; MAGNETIC RESONANCE SPECTROSCOPY; METHYLMALONYL-COA MUTASE; MODELS, CHEMICAL; MOLECULAR STRUCTURE; SUBSTRATE SPECIFICITY;

EID: 3042850004     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja039114b     Document Type: Article

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