Patterns of colonic involvement at initial presentation in ulcerative colitis: A retrospective study of 46 newly diagnosed cases

American Journal of Clinical Pathology

Volumn 122, Issue 1, 2004, Pages 94-99

  Robert, Marie E ^a   Skacel, Mark ^b   Ullman, Thomas ^c   Bernstein, Charles N ^d   Easley, Kirk ^e   Goldblum, John R ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c NEW YORK UNIVERSITY   (United States)

^d UNIVERSITY OF MANITOBA   (Canada)

^e EMORY UNIVERSITY   (United States)

Author keywords

Colonic mucosal biopsies; Crohn disease; Pathology; Rectal sparing; Ulcerative colitis

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CHRONIC DISEASE; CLINICAL ARTICLE; COLITIS; COLON BIOPSY; COLON DISEASE; COLON MUCOSA; COLON RESECTION; CONTROLLED STUDY; CROHN DISEASE; DIFFERENTIAL DIAGNOSIS; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCORING SYSTEM; ULCERATIVE COLITIS;

EID: 3042842697     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/XLXKJ84C3JCW3RCH     Document Type: Article

References (23)

1. Lewin KJ, Riddell RH, Weinstein WM, eds. In: Gastrointestinal Pathology and Its Clinical Implications. New York, NY: Igaku-Shoin; 1989:838-857.
2. Bernstein CN, Shanahan F, Anton PA, et al. Patchiness of mucosal inflammation in treated ulcerative colitis: a prospective study. Gastrointest Endosc. 1995;42:232-237.
3. D'Haens G, Geboes K, Peeters M. Patchy cecal inflammation associated with distal ulcerative colitis: a prospective endoscopic study. Am J Gastroenterol. 1997;92:1275-1279.
4. Kim B, Barnett JL, Kleer CG, et al. Endoscopic and histological patchiness in treated ulcerative colitis. Am J Gastroenterol. 1999;94:3258-3262.
5. Kleer CG, Appelman HD. Ulcerative colitis: patterns of involvement in colorectal biopsies and changes with time. Am J Surg Pathol. 1998;22:983-989.
6. Levine TS, Tzardi M, Mitchell S, et al. Diagnostic difficulty arising from rectal recovery in ulcerative colitis. J Clin Pathol. 1996;49:319-323.
7. Moum B, Vatn M, Ekbom A, et al. Endoscopic and histological evaluation of extent of disease in ulcerative colitis: differences increase from diagnosis, and until follow-up one year later [abstract]. Gastroenterology. 1997;112:A1046.
8. Odze R, Antonioli D, Peppercorn M, et al. Effect of topical 5-aminosalicylic acid (5-ASA) therapy on rectal mucosal biopsy morphology in chronic ulcerative colitis. Am J Surg Pathol. 1993;17:869-875.
9. Oshitani N, Kitano A, Nakamura S, et al. Clinical and prognostic features of rectal sparing in ulcerative colitis. Digestion. 1989;42:39-43.
10. Targan SR, Hanauer SB, van Deventer SJH, et al. A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor for Crohn's disease. N Engl J Med. 1997;337:1029-1035.
11. Nostrant TT, Kumar NB, Appelman HD. Histopathology differentiates acute self-limited colitis from ulcerative colitis. Gastroenterology. 1987;92:318-328.
12. Schumacher G, Kolberg B, Sandsstedt B. A prospective study of first attacks of inflammatory bowel disease and infectious colitis: histologic course during the first year after presentation. Histology. 1994;29:318-332.
13. Surawicz CM, Haggitt RC, Husseman M, et al. Mucosal biopsy diagnosis of colitis: acute self-limited colitis and idiopathic inflammatory bowel disease. Gastroenterology. 1994;107:755-763.
14. Jenkins D, Balsitis M, Gallivan S, et al. Guidelines for the initial biopsy diagnosis of suspected chronic idiopathic inflammatory bowel disease: the British Society of Gastroenterology Initiative. J Clin Pathol. 1997;50:93-105.
15. Tanaka M, Riddell RH, Saito H, et al. Morphologic criteria applicable to biopsy specimens for effective distinction of inflammatory bowel disease from other forms of colitis and of Crohn's disease from ulcerative colitis. Scand J Gastroenterol. 1999;34:55-67.
16. Robert ME, Tang L, Hao LM, et al. Patterns of inflammation in mucosal biopsies of ulcerative colitis: perceived differences in pediatric populations are limited to children younger than 10 years. Am J Surg Pathol. 2004;28:183-189.
17. Zeger AL, Liang KY. Longitudinal data analysis for discrete and continuous outcomes. Biometrics. 1986;42:121-130.
18. Burnham WR, Ansell ID, Langman MJ. Normal sigmoidoscopic findings in severe ulcerative colitis: an important and common occurrence [abstract]. Gut. 1980;21:A460.
19. Spiliadis CA, Spiliadis CA, Lennard-Jones JE. Ulcerative colitis with relative sparing of the rectum: clinical features, histology, and prognosis. Dis Colon Rectum. 1987;30:334-336.
20. Markowitz J, Kahn E, Grancher K, et al. Atypical rectosigmoid histology in children with newly diagnosed ulcerative colitis. Am J Gastroenterol. 1993;88:2034-2037.
21. Glickman J, Bousvaros A, Farraye F, et al. Relative rectal sparing and skip lesions are not uncommon at initial presentation in pediatric patients with chronic ulcerative colitis [abstract]. Mod Pathol. 2002;16:127A.
22. Washington K, Greenson JK, Montgomery E, et al. Histopathology of ulcerative colitis in initial rectal biopsy in children. Am J Surg Pathol. 2002;26:1441-1449.
23. Whitehead R. Mucosal Biopsy of the Gastrointestinal Tract. Philadelphia, PA: Saunders; 1990.