Determination of 14C residue in eggs of laying hens administered orally with [14C] sulfaquinoxaline

Food Additives and Contaminants

Volumn 21, Issue 6, 2004, Pages 545-554

  Shaikh, B ^a   Rummel, N ^a   Smith, D ^b  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b USDA ARS Red River Valley Agricultural Research Center   (United States)

Author keywords

Eggs; High performance liquid chromatography (HPLC) analysis; Oral dose; Sulfaquinoxaline; Total radioactive residue

Indexed keywords

CARBON 14; DRUG RESIDUE; OVALBUMIN; SULFAQUINOXALINE; ANTIINFECTIVE AGENT; CARBON; DIAGNOSTIC AGENT; EGG WHITE;

ANIMAL EXPERIMENT; ARTICLE; BIOASSAY; COMBUSTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DETERMINATION; DRUG MONITORING; DRUG WITHDRAWAL; EGG LAYING; EGG YOLK; FEMALE; FOOD ANALYSIS; FOOD CONTAMINATION; HEN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID SCINTILLATION COUNTING; NONHUMAN; PRIORITY JOURNAL; RADIATION DETECTION; RADIOACTIVE CONTAMINATION; SEPARATION TECHNIQUE; ANIMAL; ANIMAL DISEASE; CHEMISTRY; CHICKEN; EGG; FECES; METABOLISM; METHODOLOGY; ORAL DRUG ADMINISTRATION; SUBSTANCE ABUSE;

TRIXIS;

ADMINISTRATION, ORAL; ANIMALS; ANTI-INFECTIVE AGENTS; CARBON RADIOISOTOPES; CHICKENS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG RESIDUES; EGG WHITE; EGG YOLK; EGGS; FECES; FEMALE; FOOD CONTAMINATION; SUBSTANCE ABUSE DETECTION; SULFAQUINOXALINE;

EID: 3042813444     PISSN: 0265203X     EISSN: None     Source Type: Journal    
DOI: 10.1080/02652030410001687672     Document Type: Article

References (11)

1. 14C-sulfadimethoxine in Swine. Xenobiotica, 9, 921-933.
2. Barron, M. G., and James, M. O., 1994, Oral bioavailability and disposition of sulphadimethoxine in lobster. Xenobiotica, 24, 921-931.
3. 14C residues of sarafloxacin in eggs of laying hens. Journal of Agricultural Food Chemistry, 48, 6409-6411.
4. Code of Federal Regulations, Food & Drugs, Part 520, 2001 (Washington, DC: US Government Printing Office) Vol. 21, pp. 192-194.
5. Donoghue, D. J., Hairston, H., Henderson, M., McDonald, M., Gaines, S. A., and Donoghue, A. M., 1997, Modeling residue uptake by eggs: yolks contain ampicillin residues even after drug withdrawal and non-detectability in the plasma. Poultry Science, 76, 458-462.
6. Geertsma, M. F., Nouws, J. F. M., Grondel, J. L., Aerts, N. M. L., Vree, T. B. and Kan, C. A., 1987, Residues of sulfadimidine and its metabolites in eggs following oral sulfadimidine medication of hens. Veterinary Quarterly, 9, 67-75.
7. 4-acetyl derivatives in chicken tissues during frozen storage. Journal of AOAC International, 72, 486-488.
8. Righter, H. F., Worthington, J. M., Zimmerman, H. E., and Mercer, H. D., 1970, Tissue-residue depletion of sulfaquinoxaline in poultry. American Journal of Veterinary Research, 31, 1051-1054.
9. Roudaut, B., 1993, Residues of sulphonamides in eggs following oral medication of laying hens. Proceedings of the EuroResidue II Conference, vol. 2, pp. 591-595.
10. 14C] sulfamethazine administration of hens. Agriculture and Food Chemistry, 48, 6404-6408.
11. Shaikh, B., Rummel, N., and Donoghue, D., 1999, Determination of sulfamethazine and its major metabolites in egg albumen and yolk by high performance liquid chromatography. Journal of Liquid Chromatography and Related Technology, 22, 2651-2662.